The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation
细胞因子信号抑制因子中保守的SOCS盒基序可与延伸蛋白B和C结合,并可能将结合蛋白与蛋白酶体降解偶联。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.96.5.2071
Zhang, J G; Farley, A; Nicholson, S E; Willson, T A; Zugaro, L M; Simpson, R J; Moritz, R L; Cary, D; Richardson, R; Hausmann, G; Kile, B T; Kent, S B; Alexander, W S; Metcalf, D; Hilton, D J; Nicola, N A; Baca, M