Myotonic dystrophy type 1 embryonic stem cells show decreased myogenic potential, increased CpG methylation at the DMPK locus and RNA mis-splicing.
1 型强直性肌营养不良胚胎干细胞表现出肌源性潜能降低、DMPK 位点 CpG 甲基化增加和 RNA 剪接错误
期刊:Biology Open
影响因子:1.7
doi:10.1242/bio.058978
Franck Silvie, Couvreu De Deckersberg Edouard, Bubenik Jodi L, Markouli Christina, Barbé Lise, Allemeersch Joke, Hilven Pierre, Duqué Geoffrey, Swanson Maurice S, Gheldof Alexander, Spits Claudia, Sermon Karen D
