ALIX mediates reversible gasdermin-D pore formation via the endosomal pathway to limit pyroptosis by active membrane repair.
ALIX 通过内体途径介导可逆的 gasdermin-D 孔形成,通过主动膜修复来限制细胞焦亡。
期刊:Cell Death & Disease
影响因子:9.6
doi:10.1038/s41419-025-07998-y
Otchere Sylvia, Shrestha Prafulla, Parmar Himesh N, Perry Jadyn F, Hofmeister Brittany L, Steyn Michelle, Kaushik Radhey S, Hoppe Adam D, Thiex Natalie W, Hanson Ryan L, Lopez-Mosqueda Jaime, Imre Gergely