日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

RO4938581, a GABA(A)-α5 negative allosteric modulator rescued behavioral and EEG phenotypes of a mouse model of Dup15q syndrome

RO4938581 是一种 GABA(A)-α5 负变构调节剂，可改善 Dup15q 综合征小鼠模型的行为和脑电图表型。

期刊:Molecular Psychiatry
影响因子:10.1
doi:10.1038/s41380-025-03247-y
Nakagawa, Ryoko; Nani, Francesca; Hipp, Joerg F; Honer, Michael; Knoflach, Frederic; Gasser, Rodolfo; Ozmen, Laurence; Tamada, Kota; Fjeldskaar, Fatiha; Takacs, Livia; Vautheny, Audrey; Morairty, Stephen R; Saxe, Michael; Takumi, Toru; Hernandez, Maria-Clemencia
神经科学
发表日期：2026
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Local activity alterations in individuals with autism correlate with neurotransmitter properties and ketamine-induced brain changes

自闭症患者的局部活动改变与神经递质特性和氯胺酮诱导的脑部变化相关。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-63857-6
Grumbach, Pascal; Kasper, Jan; Hipp, Joerg F; Forsyth, Anna; Valk, Sofie L; Muthukumaraswamy, Suresh; Eickhoff, Simon B; Schilbach, Leonhard; Dukart, Juergen
自闭症
神经科学
发表日期：2025
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Angelman syndrome patient-derived neuron screen leads to clinical ASO rugonersen targeting UBE3A-ATS with long-lasting effect in monkeys.

安格曼综合征患者来源的神经元筛选产生了临床 ASO rugonersen，该药物靶向 UBE3A-ATS，在猴子身上具有持久疗效

期刊:Nucleic Acids Research
影响因子:13.1
doi:10.1093/nar/gkaf851
Jagasia Ravi, Bon Charlotte, Rasmussen Soren V, Badillo Solveig, Tehler Disa, Buchy Danièle, Berrera Marco, Prasad Megana, Chamberlain Stormy, Terrigno Marco, Pandya Nikhil J, Costa Veronica, Wang Congwei, Pedersen Lykke, Miller Meghan T, Erichsen Kamille Dumong, Joenson Lars, Patsch Christoph, Hipp Joerg F, Bonni Azad, Müller Lutz, Braendli-Baiocco Annamaria, Kremer Thomas, Koller Erich, Hoener Marius C
神经科学
发表日期：2025
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Preclinical pharmacology of alogabat: a novel GABA(A)-α5 positive allosteric modulator targeting neurodevelopmental disorders with impaired GABA(A) signaling

alogabat 的临床前药理学研究：一种新型 GABA(A)-α5 正向变构调节剂，靶向治疗 GABA(A) 信号传导受损的神经发育障碍

期刊:Frontiers in Pharmacology
影响因子:4.8
doi:10.3389/fphar.2025.1626078
Cecere, Giuseppe; Ballard, Theresa M; Knoflach, Frederic; Honer, Michael; Hipp, Joerg F; Garces, Pilar; Mueggler, Thomas; Künnecke, Basil; Bruns, Andreas; Prinssen, Eric P; Schoenenberger, Philipp; Janz, Philipp; Redondo, Roger; Biemans, Barbara; Knust, Henner; Olivares-Morales, Andrés; Brigo, Alessandro; Schulz, Jan Michael; Bertrand, Daniel; Saxe, Michael; O'Connor, Eoin C; Hernandez, Maria-Clemencia
信号转导
发育与干细胞
神经科学
发表日期：2025
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Local activity alterations in autism spectrum disorder correlate with neurotransmitter properties and ketamine induced brain changes

自闭症谱系障碍患者的局部活动改变与神经递质特性和氯胺酮诱导的脑部变化相关。

期刊:
影响因子:
doi:10.1101/2024.10.20.24315801
Grumbach, Pascal; Kasper, Jan; Hipp, Joerg F; Forsyth, Anna; Valk, Sofie L; Muthukumaraswamy, Suresh; Eickhoff, Simon B; Schilbach, Leonhard; Dukart, Juergen
自闭症
神经科学
发表日期：2024
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Functional connectivity signatures of NMDAR dysfunction in schizophrenia-integrating findings from imaging genetics and pharmaco-fMRI

精神分裂症中NMDAR功能障碍的功能连接特征——整合影像遗传学和药理功能磁共振成像的研究结果

期刊:Translational Psychiatry
影响因子:6.2
doi:10.1038/s41398-023-02344-2
Gaebler, Arnim J; Fakour, Nilüfer; Stöhr, Felix; Zweerings, Jana; Taebi, Arezoo; Suslova, Mariia; Dukart, Juergen; Hipp, Joerg F; Adhikari, Bhim M; Kochunov, Peter; Muthukumaraswamy, Suresh D; Forsyth, Anna; Eggermann, Thomas; Kraft, Florian; Kurth, Ingo; Paulzen, Michael; Gründer, Gerhard; Schneider, Frank; Mathiak, Klaus
精神分裂症
神经科学
发表日期：2023
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Enabling endpoint development for interventional clinical trials in individuals with Angelman syndrome: a prospective, longitudinal, observational clinical study (FREESIAS)

为安格曼综合征患者介入性临床试验开发终点指标：一项前瞻性、纵向、观察性临床研究（FREESIAS）

期刊:Journal of Neurodevelopmental Disorders
影响因子:4
doi:10.1186/s11689-023-09494-w
Tjeertes, Jorrit; Bacino, Carlos A; Bichell, Terry Jo; Bird, Lynne M; Bustamante, Mariana; Crean, Rebecca; Jeste, Shafali; Komorowski, Robert W; Krishnan, Michelle L; Miller, Meghan T; Nobbs, David; Ochoa-Lubinoff, Cesar; Parkerson, Kimberly A; Rotenberg, Alexander; Sadhwani, Anjali; Shen, Mark D; Squassante, Lisa; Tan, Wen-Hann; Vincenzi, Brenda; Wheeler, Anne C; Hipp, Joerg F; Berry-Kravis, Elizabeth
发表日期：2023
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Resting state EEG power spectrum and functional connectivity in autism: a cross-sectional analysis

自闭症患者静息态脑电功率谱和功能连接：一项横断面分析

期刊:Molecular Autism
影响因子:5.5
doi:10.1186/s13229-022-00500-x
Garcés, Pilar; Baumeister, Sarah; Mason, Luke; Chatham, Christopher H; Holiga, Stefan; Dukart, Juergen; Jones, Emily J H; Banaschewski, Tobias; Baron-Cohen, Simon; Bölte, Sven; Buitelaar, Jan K; Durston, Sarah; Oranje, Bob; Persico, Antonio M; Beckmann, Christian F; Bougeron, Thomas; Dell'Acqua, Flavio; Ecker, Christine; Moessnang, Carolin; Charman, Tony; Tillmann, Julian; Murphy, Declan G M; Johnson, Mark; Loth, Eva; Brandeis, Daniel; Hipp, Joerg F
自闭症
神经科学
发表日期：2022
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Neural complexity is a common denominator of human consciousness across diverse regimes of cortical dynamics

神经复杂性是人类意识在各种皮层动力学状态下的共同特征。

期刊:Communications Biology
影响因子:5.1
doi:10.1038/s42003-022-04331-7
Frohlich, Joel; Chiang, Jeffrey N; Mediano, Pedro A M; Nespeca, Mark; Saravanapandian, Vidya; Toker, Daniel; Dell'Italia, John; Hipp, Joerg F; Jeste, Shafali S; Chu, Catherine J; Bird, Lynne M; Monti, Martin M
发表日期：2022
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A randomized, double-blind, placebo-controlled phase II trial to explore the effects of a GABA(A)-α5 NAM (basmisanil) on intellectual disability associated with Down syndrome

一项随机、双盲、安慰剂对照的II期临床试验，旨在探索GABA(A)-α5 NAM（巴斯米沙尼）对唐氏综合征相关智力障碍的影响。

期刊:Journal of Neurodevelopmental Disorders
影响因子:4
doi:10.1186/s11689-022-09418-0
Goeldner, Celia; Kishnani, Priya S; Skotko, Brian G; Casero, Julian Lirio; Hipp, Joerg F; Derks, Michael; Hernandez, Maria-Clemencia; Khwaja, Omar; Lennon-Chrimes, Sian; Noeldeke, Jana; Pellicer, Sabine; Squassante, Lisa; Visootsak, Jeannie; Wandel, Christoph; Fontoura, Paulo; d'Ardhuy, Xavier Liogier
发表日期：2022
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