Suppression of insulin signalling by a synthetic peptide KIFMK suggests the cytoplasmic linker between DIII-S6 and DIV-S1 as a local anaesthetic binding site on the sodium channel.
合成肽 KIFMK 对胰岛素信号的抑制表明 DIII-S6 和 DIV-S1 之间的胞质连接子是钠通道上的局部麻醉剂结合位点
期刊:British Journal of Pharmacology
影响因子:7.7
doi:10.1038/sj.bjp.0705575
Hirose Munetaka, Kuroda Yoshihiro, Sawa Shinichi, Nakagawa Terumichi, Hirata Masashi, Sakaguchi Masahiro, Tanaka Yoshifumi
