日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Investigation of Profile-Related Evidence Determining Individualized Cancer Therapy (I-PREDICT) N-of-1 Precision Oncology Study: Molecular Profiling to Match Individually Dosed, Personalized Drug Combinations

基于分子谱分析确定个体化癌症治疗的证据调查（I-PREDICT）N-of-1精准肿瘤学研究：分子谱分析匹配个体化给药的个性化药物组合

期刊:Journal of Clinical Oncology
影响因子:41.9
doi:10.1200/JCO-25-01453
Sicklick, Jason K; Nishizaki, Daisuke; Miyashita, Hirotaka; Okamura, Ryosuke; Hahn, Michael E; Nikanjam, Mina; Fanta, Paul T; Piccioni, David E; Patel, Hitendra; Eskander, Ramez N; McKay, Rana R; Ross, Jeffrey S; Lee, J Jack; Lippman, Scott M; Kato, Shumei; Kurzrock, Razelle
肿瘤
RED
肿瘤免疫
发表日期：2026
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Phosphorylation of Runx protein controls helper CD4(+) T cell versus cytotoxic CD8(+) T cell lineage choice

Runx蛋白的磷酸化控制辅助性CD4(+) T细胞与细胞毒性CD8(+) T细胞的谱系选择

期刊:Nature Immunology
影响因子:27.6
doi:10.1038/s41590-026-02441-6
Ogawa, Chihiro; Okuyama, Kazuki; Kojo, Satoshi; Nishino, Kohei; Machiyama, Hiroaki; Padhi, Aditya K; Takahashi, Hirotaka; Ebihara, Takashi; Tenno, Mari; Zhizhen, Qin; Muroi, Sawako; Ito, Kosei; Sawasaki, Tatsuya; Zhang, Kam Y J; Xue, Hai-Hui; Yokosuka, Tadashi; Kosako, Hidetaka; Taniuchi, Ichiro
T细胞
信号转导
CD8
T细胞
磷酸化
细胞生物学
毒理研究
CD4
免疫/内分泌
发表日期：2026
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CARDBiomedBench: a benchmark for evaluating the performance of large language models in biomedical research

CARDBiomedBench：用于评估大型语言模型在生物医学研究中性能的基准测试

期刊:Lancet Digital Health
影响因子:24.1
doi:10.1016/j.landig.2025.100943
Bianchi, Owen; Willey, Maya; Alvarado, Chelsea X; Danek, Benjamin; Khani, Marzieh; Kuznetsov, Nicole; Dadu, Anant; Shah, Syed; Koretsky, Mathew J; Makarious, Mary B; Weller, Cory; Levine, Kristin S; Kim, Sungwon; Jarreau, Paige; Vitale, Dan; Marsan, Elise; Iwaki, Hirotaka; Leonard, Hampton; Bandres-Ciga, Sara; Singleton, Andrew B; Nalls, Mike A; Mokhtari, Shekoofeh; Khashabi, Daniel; Faghri, Faraz
发表日期：2026
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Clinical Images: Methotrexate-induced melanonychia

临床图片：甲氨蝶呤引起的黑甲症

期刊:Arthritis & Rheumatology
影响因子:10.9
doi:10.1002/art.43340
Taniguchi, Yoshinori; Yamamoto, Hirotaka
发表日期：2026
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High-Fat Diet-Fed Kcnq1 Mutant Mice Have Reduced Pancreatic β-Cell Mass via Gene-Environment Interaction

高脂饮食喂养的Kcnq1突变小鼠通过基因-环境相互作用导致胰腺β细胞数量减少

期刊:Diabetes & Metabolism Journal
影响因子:8.5
doi:10.4093/dmj.2024.0790
Asahara, Shun-Ichiro; Inoue, Hiroyuki; Ihara, Yuka; Teruyama, Kyoko; Imai, Asuka; Hara, Chisako; Hara, Mizuki; Seike, Masako; Yokoi, Aisha; Kido, Nozomi; Suzuki, Hirotaka; Kanno, Ayumi; Inaba, Yuka; Watanabe, Hitoshi; Shioi, Go; Kimura-Koyanagi, Maki; Matsumoto, Michihiro; Inoue, Hiroshi; Nakayama, Keiichi I; Ogawa, Wataru; Kasuga, Masato; Kido, Yoshiaki
细胞生物学
发表日期：2026
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FOXM1 down-regulation is a trigger of isatuximab-induced direct cell death in multiple myeloma cells with 1q

FOXM1下调是1q多发性骨髓瘤细胞中isatuximab诱导直接细胞死亡的触发因素。

期刊:Haematologica
影响因子:7.9
doi:10.3324/haematol.2025.287904
Kikuchi, Jiro; Osada, Naoki; Matsuoka, Sae; Ohta, Tomomi; Kazama, Hirotaka; Shirai, Heigoro; Meloni, Marco; Chiron, Marielle; Yasui, Hiroshi; Nakasone, Hideki; Furukawa, Yusuke
FOXM1
多发性骨髓瘤
细胞生物学
骨髓瘤
发表日期：2026
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Hyper-maturity and accelerated aging in the hippocampus of mouse models of neuropsychiatric disorders with anxiety-like behavior

焦虑样行为的神经精神疾病小鼠模型海马体出现过度成熟和加速衰老现象

期刊:Neuropsychopharmacology
影响因子:7.1
doi:10.1038/s41386-025-02237-6
Hagihara, Hideo; Koshimizu, Hisatsugu; Hattori, Satoko; Shoji, Hirotaka; Tanaka, Miho; Ikeda, Kazutaka; Miyakawa, Tsuyoshi
衰老
发表日期：2026
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Correction: Post-radiation targeting of TIGIT and CD96 improved immunotherapy efficacy in head and neck squamous cell carcinoma

更正：放射治疗后靶向 TIGIT 和 CD96 可提高头颈部鳞状细胞癌的免疫治疗疗效

期刊:Molecular Medicine
影响因子:6.4
doi:10.1186/s10020-026-01447-y
Salah, Mohammed; Saito, Masafumi; Kawaguchi, Hiroki; Shimizu, Yasuyuki; Fujita, Yoshiko; Mukumoto, Naritoshi; Kotani, Joji; Shinomiya, Hirotaka; Ishihara, Takeaki; Miyawaki, Daisuke; Nibu, Nen-Ichi; Sasaki, Ryohei
肿瘤
肿瘤免疫
CD96
CD9
TIGIT
细胞生物学
免疫/内分泌
发表日期：2026
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Data-driven schizophrenia subtyping via brain atrophy trajectories and functional connectivity

基于脑萎缩轨迹和功能连接的数据驱动型精神分裂症亚型分类

期刊:Translational Psychiatry
影响因子:6.2
doi:10.1038/s41398-026-03968-w
Yoshimaru, Daisuke; Ouchi, Kazuya; Shibukawa, Shuhei; Ozawa, Masakazu; Hirabayashi, Motoki; Yuzawa, Ami; Tsurugizawa, Tomokazu; Oishi, Kenichi; Okano, Hirotaka James
精神分裂症
神经科学
发表日期：2026
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Histological grade 2 and non-contrast-enhancing phenotype provide prognostic information complementary to DNA methylation classification in TERTp-mutant molecular glioblastomas

组织学分级 2 级和非增强表型可提供与 DNA 甲基化分类互补的 TERTp 突变分子胶质母细胞瘤预后信息。

期刊:Acta Neuropathologica Communications
影响因子:5.7
doi:10.1186/s40478-026-02269-z
Sueyoshi, Hiroyuki; Fujimoto, Kenji; Fujita, Katsumi; Tanaka, Kazuhito; Inoue, Hirotaka; Yamada, Rin; Yamamoto, Takahiro; Nakachi, Yutaka; Kuroda, Jun-Ichiro; Shinojima, Naoki; Iwamoto, Kazuya; Mikami, Yoshiki; Mukasa, Akitake
细胞生物学
表观遗传
TERT
发表日期：2026
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