日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Caenorhabditis elegans fed native gut microbiota have altered bioenergetic pathway utilization impacting mitochondrial function and susceptibility to pollutants

以天然肠道微生物群为食的秀丽隐杆线虫的生物能量途径利用发生改变,从而影响线粒体功能和对污染物的敏感性。

Bergemann, Christina M; Jameson, Laura E; Kenny-Ganzert, Isabel W; Huayta, Javier; Castellano-Escuder, Pol; Sarkar, Arunabh; Ilkayeva, Olga R; Sherwood, David R; Hirschey, Matthew D; Meyer, Joel N

datadrivenhypothesis.org: A resource for metabolic gene discovery through integrated pathway co-essentiality mapping

datadrivenhypothesis.org:一个通过整合通路共必需性映射进行代谢基因发现的资源。

Hirschey, Matthew D; Castellano-Escuder, Pol; Bradley, John

Pathway coessentiality mapping reveals complex II is required for de novo purine biosynthesis in acute myeloid leukaemia

通路共必需性分析揭示复合物 II 是急性髓系白血病中嘌呤从头合成所必需的

Stewart, Amy E; Zachman, Derek K; Castellano-Escuder, Pol; Kelly, Lois M; Zolyomi, Ben; Aiduk, Michael D I; Delaney, Christopher D; Lock, Ian C; Bosc, Claudie; Bradley, John; Killarney, Shane T; Stuart, J Darren; Grimsrud, Paul A; Ilkayeva, Olga R; Newgard, Christopher B; Chandel, Navdeep S; Puissant, Alexandre; Wood, Kris C; Hirschey, Matthew D

Targeting androgen receptor signaling to enhance cancer immunotherapy

靶向雄激素受体信号通路以增强癌症免疫疗法

Bader, David A; Chakraborty, Binita; McDonnell, Donald P; Hirschey, Matthew D

ABCA7 Loss of Function Variants Disrupt Neuronal Lipid Metabolism and Respiration

ABCA7功能缺失变异体破坏神经元脂质代谢和呼吸作用

Luz, Anthony T; Godebo, Tewodros R; Bhatt, Dhaval P; Ilkayeva, Olga R; Maurer, Laura L; Hirschey, Matthew D; Meyer, Joel N; Maydell, Djuna K Von; Wright, Shannon; Staab, Colin; Pao, Ping‐Chieh; King, Oisin; Bonner, Julia Maeve; Spitaleri, Andrea; Liu, Liwang; Chiu, Ching‐Chi; Leible, Daniel; Yu, Chung Jong; Scannail, Aine Ni; Li, Mingpei; Boix, Carles A; Mathys, Hansruedi; Leclerc, Guillaume; Menchaca, Gloria Suella; Welch, Gwyneth; Graziosi, Agnese; Leary, Noelle; Samaan, George; Kellis, Manolis; Tsai, Li‐Huei

Pathway Coessentiality Mapping Reveals Complex II is Required for de novo Purine Biosynthesis in Acute Myeloid Leukemia

通路共必需性分析揭示复合物 II 是急性髓系白血病中嘌呤从头合成所必需的

Stewart, Amy E; Zachman, Derek K; Castellano-Escuder, Pol; Kelly, Lois M; Zolyomi, Ben; Aiduk, Michael D I; Delaney, Christopher D; Lock, Ian C; Bosc, Claudie; Bradley, John; Killarney, Shane T; Ilkayeva, Olga R; Newgard, Christopher B; Chandel, Navdeep S; Puissant, Alexandre; Wood, Kris C; Hirschey, Matthew D

Cysteine S-acetylation is a widespread post-translational modification on metabolic proteins

半胱氨酸S-乙酰化是代谢蛋白上广泛存在的翻译后修饰。

Keenan, E Keith; Bareja, Akshay; Lam, Yannie; Grimsrud, Paul A; Hirschey, Matthew D

SIRT4 Controls Macrophage Function and Wound Healing through Control of Protein Itaconylation in Mice

SIRT4通过调控小鼠体内蛋白质衣康酰化来控制巨噬细胞功能和伤口愈合

Anderson, Kristin A; deSouza, Beverly; Castellano-Escuder, Pol; Lin, Zhihong; Ilkayeva, Olga R; Muehlbauer, Michael J; Grimsrud, Paul A; Hirschey, Matthew D

Cysteine S-acetylation is a post-translational modification involved in metabolic regulation.

半胱氨酸S-乙酰化是一种参与代谢调控的翻译后修饰

Keenan E Keith, Bareja Akshay, Lam Yannie, Grimsrud Paul A, Hirschey Matthew D

Discovering the landscape of protein modifications

探索蛋白质修饰的全貌

Keenan, E Keith; Zachman, Derek K; Hirschey, Matthew D