Hitoshi Okazawa相关文献与解析，生知库 | 链接生命科学的每一步

Yasuhiro Nemoto ，Ryo Morikawa ，Yuki Yonemoto ，Shohei Tanaka ，Yuria Takei ，Shigeru Oshima ，Takashi Nagaishi ，Kiichiro Tsuchiya ，Tetsuya Nakamura ，Kento Takenaka ，Kazuo Ohtsuka ，Xigui Chen ，Hitoshi Okazawa ，Ryuichi Okamoto ，Mamoru Watanabe ，Ulrich H von Andrian

T细胞

CD8

T细胞

PQBP3 prevents senescence by suppressing PSME3-mediated proteasomal Lamin B1 degradation

PQBP3通过抑制PSME3介导的蛋白酶体对层粘蛋白B1的降解来阻止衰老。

期刊:EMBO Journal

影响因子:9.4

doi:10.1038/s44318-024-00192-4

Yuki Yoshioka # ,Yong Huang # ,Xiaocen Jin # ,Kien Xuan Ngo # ,Tomohiro Kumaki ,Meihua Jin ,Saori Toyoda ,Sumire Takayama ,Maiko Inotsume ,Kyota Fujita ,Hidenori Homma ,Toshio Ando ,Hikari Tanaka # ,Hitoshi Okazawa

衰老

发表日期：2024

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Dynamic molecular network analysis of iPSC-Purkinje cells differentiation delineates roles of ISG15 in SCA1 at the earliest stage

对iPSC-浦肯野细胞分化的动态分子网络分析揭示了ISG15在SCA1早期阶段的作用

期刊:Communications Biology

影响因子:5.2

doi:10.1038/s42003-024-06066-z

Hidenori Homma # ,Yuki Yoshioka # ,Kyota Fujita # ,Shinichi Shirai ,Yuka Hama ,Hajime Komano ,Yuko Saito ,Ichiro Yabe ,Hideyuki Okano ,Hidenao Sasaki ,Hikari Tanaka ,Hitoshi Okazawa

PQBP5/NOL10 maintains and anchors the nucleolus under physiological and osmotic stress conditions

PQBP5/NOL10 在生理和渗透胁迫条件下维持和锚定核仁

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-022-35602-w

Xiaocen Jin #, Hikari Tanaka #, Meihua Jin, Kyota Fujita, Hidenori Homma, Maiko Inotsume, Huang Yong, Kenichi Umeda, Noriyuki Kodera, Toshio Ando, Hitoshi Okazawa

Analyzing schizophrenia-related phenotypes in mice caused by autoantibodies against NRXN1α in schizophrenia

分析精神分裂症患者自身抗体NRXN1α引起的小鼠精神分裂症相关表型

期刊:Brain Behavior and Immunity

影响因子:8.8

doi:10.1016/j.bbi.2023.03.028

Hiroki Shiwaku, Shingo Katayama, Mengxuan Gao, Kanoh Kondo, Yuri Nakano, Yukiko Motokawa, Saori Toyoda, Fuyuko Yoshida, Hiroaki Hori, Tetsuo Kubota, Kinya Ishikawa, Hiroshi Kunugi, Yuji Ikegaya, Hitoshi Okazawa, Hidehiko Takahashi

AAV-mediated editing of PMP22 rescues Charcot-Marie-Tooth disease type 1A features in patient-derived iPS Schwann cells

AAV 介导的 PMP22 编辑挽救了患者来源的 iPS 施旺细胞中的 1A 型腓骨肌萎缩症特征

期刊:Commun Med (Lond)

影响因子:

doi:10.1038/s43856-023-00400-y

Yuki Yoshioka #, Juliana Bosso Taniguchi #, Hidenori Homma #, Takuya Tamura, Kyota Fujita, Maiko Inotsume, Kazuhiko Tagawa, Kazuharu Misawa, Naomichi Matsumoto, Masanori Nakagawa, Haruhisa Inoue, Hikari Tanaka, Hitoshi Okazawa

Autoantibodies against NCAM1 from patients with schizophrenia cause schizophrenia-related behavior and changes in synapses in mice

精神分裂症患者体内针对NCAM1的自身抗体可导致小鼠出现与精神分裂症相关的行为和突触改变。

期刊:Cell Reports Medicine

影响因子:11.7

doi:10.1016/j.xcrm.2022.100597

Hiroki Shiwaku,Shingo Katayama,Kanoh Kondo,Yuri Nakano,Hikari Tanaka,Yuki Yoshioka,Kyota Fujita,Haruna Tamaki,Hironao Takebayashi,Omi Terasaki,Yukihiro Nagase,Teruyoshi Nagase,Tetsuo Kubota,Kinya Ishikawa,Hitoshi Okazawa,Hidehiko Takahashi

Tau activates microglia via the PQBP1-cGAS-STING pathway to promote brain inflammation

Tau 通过 PQBP1-cGAS-STING 通路激活小胶质细胞，促进脑部炎症

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-021-26851-2

Meihua Jin #, Hiroki Shiwaku #, Hikari Tanaka #, Takayuki Obita, Sakurako Ohuchi, Yuki Yoshioka, Xiaocen Jin, Kanoh Kondo, Kyota Fujita, Hidenori Homma, Kazuyuki Nakajima, Mineyuki Mizuguchi, Hitoshi Okazawa

信号转导

细胞生物学

胶质细胞

Immunology/Inflammation

Prediction and verification of the AD-FTLD common pathomechanism based on dynamic molecular network analysis

基于动态分子网络分析预测及验证AD-FTLD共同致病机制

期刊:Communications Biology

影响因子:5.2

doi:10.1038/s42003-021-02475-6

Meihua Jin #, Xiaocen Jin #, Hidenori Homma #, Kyota Fujita, Hikari Tanaka, Shigeo Murayama, Hiroyasu Akatsu, Kazuhiko Tagawa, Hitoshi Okazawa

HMGB1 signaling phosphorylates Ku70 and impairs DNA damage repair in Alzheimer's disease pathology

HMGB1信号通路磷酸化Ku70，并损害阿尔茨海默病病理中的DNA损伤修复。

期刊:Communications Biology

影响因子:5.2

doi:10.1038/s42003-021-02671-4

Hikari Tanaka # ，Kanoh Kondo # ，Kyota Fujita # ，Hidenori Homma # ，Kazuhiko Tagawa ，Xiaocen Jin ，Meihua Jin ，Yuki Yoshioka ，Sumire Takayama ，Hitomi Masuda ，Rie Tokuyama ，Yukoh Nakazaki ，Takashi Saito ，Takaomi Saido ，Shigeo Murayama ，Teikichi Ikura ，Nobutoshi Ito ，Yu Yamamori ，Kentaro Tomii ，Marco E Bianchi ，Hitoshi Okazawa

Intestinal CD4-CD8αβ-TCRαβ+ T cells function as tolerogenic antigen presenting cells in mice

小鼠肠道CD4-CD8αβ-TCRαβ+ T细胞作为耐受性抗原呈递细胞发挥作用。

PQBP3 prevents senescence by suppressing PSME3-mediated proteasomal Lamin B1 degradation

PQBP3通过抑制PSME3介导的蛋白酶体对层粘蛋白B1的降解来阻止衰老。

Dynamic molecular network analysis of iPSC-Purkinje cells differentiation delineates roles of ISG15 in SCA1 at the earliest stage

对iPSC-浦肯野细胞分化的动态分子网络分析揭示了ISG15在SCA1早期阶段的作用

PQBP5/NOL10 maintains and anchors the nucleolus under physiological and osmotic stress conditions

PQBP5/NOL10 在生理和渗透胁迫条件下维持和锚定核仁

Analyzing schizophrenia-related phenotypes in mice caused by autoantibodies against NRXN1α in schizophrenia

分析精神分裂症患者自身抗体NRXN1α引起的小鼠精神分裂症相关表型

AAV-mediated editing of PMP22 rescues Charcot-Marie-Tooth disease type 1A features in patient-derived iPS Schwann cells

AAV 介导的 PMP22 编辑挽救了患者来源的 iPS 施旺细胞中的 1A 型腓骨肌萎缩症特征

Autoantibodies against NCAM1 from patients with schizophrenia cause schizophrenia-related behavior and changes in synapses in mice

精神分裂症患者体内针对NCAM1的自身抗体可导致小鼠出现与精神分裂症相关的行为和突触改变。

Tau activates microglia via the PQBP1-cGAS-STING pathway to promote brain inflammation

Tau 通过 PQBP1-cGAS-STING 通路激活小胶质细胞，促进脑部炎症

Prediction and verification of the AD-FTLD common pathomechanism based on dynamic molecular network analysis

基于动态分子网络分析预测及验证AD-FTLD共同致病机制

HMGB1 signaling phosphorylates Ku70 and impairs DNA damage repair in Alzheimer's disease pathology

HMGB1信号通路磷酸化Ku70，并损害阿尔茨海默病病理中的DNA损伤修复。