日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Precision Oncology for Pediatric Solid Tumors Using In-Hospital Pediatric/AYA Malignancy-Specific Panel Sequencing

利用院内儿科/AYA恶性肿瘤特异性panel测序进行儿科实体瘤精准肿瘤学研究

期刊:Cancer Science
影响因子:4.3
doi:10.1111/cas.70312
Kojima, Masato; Kurihara, Sho; Saeki, Isamu; Touge, Ryo; Nakashima, Keigo; Karakawa, Shuhei; Yamasaki, Fumiyuki; Okada, Satoshi; Hiyama, Eiso
肿瘤
肿瘤免疫
发表日期：2026
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Mechanistic models position ceritinib as a nuclear integrity disrupting therapy in pediatric liver tumors

机制模型将色瑞替尼定位为一种破坏核完整性的儿童肝肿瘤治疗方法。

期刊:Journal of Experimental & Clinical Cancer Research
影响因子:12.8
doi:10.1186/s13046-025-03535-z
Demir, Salih; Kessler, Thomas; Hotes, Alina; Häberle, Beate; Hiyama, Eiso; Hishiki, Tomoro; Indersie, Emilie; Branchereau, Sophie; Vokuhl, Christian; Dorel, Mathurin; Lehrach, Hans; Lange, Bodo; Cairo, Stefano; Kappler, Roland
肿瘤
肿瘤免疫
发表日期：2025
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Targeting HSP90 with Ganetespib to Induce CDK1 Degradation and Promote Cell Death in Hepatoblastoma

利用 Ganetespib 靶向 HSP90 诱导 CDK1 降解并促进肝母细胞瘤细胞死亡

期刊:Cancers
影响因子:4.4
doi:10.3390/cancers17081341
Jung, Lea Amelie; Demir, Salih; Hotes, Alina; Hiyama, Eiso; Hishiki, Tomoro; Indersie, Emilie; Branchereau, Sophie; Cairo, Stefano; Kappler, Roland
细胞生物学
CDK1
HSP90
发表日期：2025
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ADAM32 Oncogene in Hepatoblastoma Is Regulated by IGF2BP2.

肝母细胞瘤中的ADAM32癌基因受IGF2BP2调控

期刊:Cancers
影响因子:4.4
doi:10.3390/cancers17111772
Fukazawa Takahiro, Tanimoto Keiji, Kojima Masato, Kanawa Masami, Hirohashi Nobuyuki, Hiyama Eiso
细胞生物学
肿瘤免疫
发表日期：2025
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Unique Function in Cancer Stemness and Prognostic Significance of EMX2 in Esophageal Squamous Cell Carcinoma.

EMX2在食管鳞状细胞癌中的独特功能及其在癌症干细胞特性和预后中的意义

期刊:Biomedicines
影响因子:3.9
doi:10.3390/biomedicines13061373
Fumoto Shoichi, Tanimoto Keiji, Noguchi Takuya, Hihara Jun, Hiyama Eiso, Otani Keiko, Ohtaki Megu, Shimada Yutaka, Nishiyama Masahiko, Hiyama Keiko
发育与干细胞
细胞生物学
发表日期：2025
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Identification of a Growth-Promoting Gene Cluster in the Region 2q24 as a Driver of Tumorigenesis in Childhood Hepatoblastoma.

鉴定出 2q24 区域的促生长基因簇是儿童肝母细胞瘤肿瘤发生的驱动因素

期刊:American Journal of Pathology
影响因子:3.6
doi:10.1016/j.ajpath.2025.04.006
Rodemann Martin M, Dreschmann Verena, Dörner Evelyn, Sommer Anette, Kraetzschmar Joern, Klein-Hitpass Ludger, Nagae Genta, Hiyama Eiso, von Schweinitz Dietrich, Kappler Roland, Vokuhl Christian, Pietsch Torsten
肿瘤
发表日期：2025
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Clinical diagnostic performance of droplet digital PCR for pathogen detection in patients with Escherichia coli bloodstream infection: a prospective observational study

液滴数字PCR检测大肠杆菌血流感染患者病原体的临床诊断性能：一项前瞻性观察研究

期刊:BMC Infectious Diseases
影响因子:3
doi:10.1186/s12879-024-10396-y
Kitagawa, Hiroki; Kojima, Masato; Tadera, Kayoko; Kogasaki, Shuta; Omori, Keitaro; Nomura, Toshihito; Shigemoto, Norifumi; Hiyama, Eiso; Ohge, Hiroki
炎症/感染
流感
微生物学
发表日期：2025
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Comprehensive Genomic Profiling Testing for Castration-Resistant Prostate Cancer in Advanced Elderly Patients: A Single-Center Retrospective Cohort Study

对晚期老年去势抵抗性前列腺癌患者进行全面的基因组分析检测：一项单中心回顾性队列研究

期刊:Prostate
影响因子:2.5
doi:10.1002/pros.24926
Fukushima, Takafumi; Goto, Keisuke; Nakano, Yoshinori; Tasaka, Shinsaku; Iwane, Kyohsuke; Tasaka, Ryo; Kobatake, Kohei; Goriki, Akihiro; Toshida, Asuka; Abe, Akiko; Ishihara, Misako; Nakahara, Hikaru; Motonaga, Masanori; Tokumo, Kentaro; Fujii, Yasutoshi; Clair Nelson, Hayes; Niitsu, Hiroaki; Ohara, Shinya; Urabe, Yuji; Okamoto, Wataru; Hiyama, Eiso; Arihiro, Koji; Hinoi, Takao; Hinata, Nobuyuki
肿瘤
前列腺癌
肿瘤免疫
发表日期：2025
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Single-cell multiomics reveals the interplay of clonal evolution and cellular plasticity in hepatoblastoma.

单细胞多组学揭示了肝母细胞瘤中克隆演化和细胞可塑性的相互作用

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-024-47280-x
Roehrig Amélie, Hirsch Theo Z, Pire Aurore, Morcrette Guillaume, Gupta Barkha, Marcaillou Charles, Imbeaud Sandrine, Chardot Christophe, Gonzales Emmanuel, Jacquemin Emmanuel, Sekiguchi Masahiro, Takita Junko, Nagae Genta, Hiyama Eiso, Guérin Florent, Fabre Monique, Aerts Isabelle, Taque Sophie, Laithier Véronique, Branchereau Sophie, Guettier Catherine, Brugières Laurence, Fresneau Brice, Zucman-Rossi Jessica, Letouzé Eric
细胞生物学
发表日期：2024
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Drug prioritization identifies panobinostat as a tailored treatment element for patients with metastatic hepatoblastoma

药物优先排序确定帕比司他为转移性肝母细胞瘤患者的个体化治疗方案。

期刊:Journal of Experimental & Clinical Cancer Research
影响因子:12.8
doi:10.1186/s13046-024-03221-6
Demir, Salih; Hotes, Alina; Schmid, Tanja; Cairo, Stefano; Indersie, Emilie; Pisano, Claudio; Hiyama, Eiso; Hishiki, Tomoro; Vokuhl, Christian; Branchereau, Sophie; Brock, Penelope; Schmid, Irene; Zsiros, József; Kappler, Roland
细胞生物学
发表日期：2024
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