日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

LP.8.1-directed COVID-19 mRNA vaccines durably boost neutralizing antibodies and mitigate ancestral immune imprinting

针对LP.8.1的COVID-19 mRNA疫苗可持久增强中和抗体并减轻祖先免疫印记

期刊:
影响因子:
doi:10.64898/2026.01.03.697434
Mellis, Ian A; Wu, Madeline; Hong, Hsiang; Bowen, Anthony; Daniel, Kristin; Gherasim, Carmen; Pierce, Virginia M; Yin, Michael T; Gordon, Aubree; Guo, Yicheng; Ho, David D
免疫/内分泌
发表日期：2026
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Distinct allosteric remodeling of HIV-1 Env dynamics on virions by gp41-directed antibodies reveals two modes of neutralization

针对病毒颗粒的gp41抗体对HIV-1 Env动力学的独特变构重塑揭示了两种中和模式

期刊:
影响因子:
doi:10.64898/2026.01.27.702099
Xu, Wang; Gonepudi, Narendra Kumar; Liu, Junyu; He, Yufan; Katte, Revansiddha; Wang, Ran; Awuah, Harry Baffour; Han, Yang; Zhang, Baoshan; Yu, Jian; Hu, Bo; Ho, David D; Acharya, Priyamvada; Kwong, Peter D; Lu, Maolin
HIV
微生物学
发表日期：2026
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ACE-2-like Enzymatic Activity in Anti-SARS-CoV-2 Spike Protein Monoclonal Antibodies

抗SARS-CoV-2刺突蛋白单克隆抗体中的ACE-2样酶活性

期刊:
影响因子:
doi:10.64898/2026.02.02.703244
Song, Yufeng; Mehl, Frances; No, Tom; Livingston, Lauren; Quintero Barbosa, Juan Sebastian; Hayashi, Jun; Serrero, Ginette; Bortz, Pamela Schoppee; Wilson, Jeffrey; Crowe, James E; Ho, David D; Yin, Michael T; Tan, Joshua; Zeichner, Steven L
单克隆抗体
SARS-CoV-2
发表日期：2026
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KP.2-based monovalent mRNA vaccines robustly boost antibody responses to SARS-CoV-2

基于KP.2的单价mRNA疫苗可显著增强对SARS-CoV-2的抗体反应。

期刊:Lancet Infectious Diseases
影响因子:31
doi:10.1016/S1473-3099(25)00058-1
Wang, Qian; Mellis, Ian A; Wu, Madeline; Bowen, Anthony; Gherasim, Carmen; Valdez, Riccardo; Shah, Jayesh G; Purpura, Lawrence J; Yin, Michael T; Gordon, Aubree; Guo, Yicheng; Ho, David D
SARS-CoV-2
发表日期：2025
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Variant-specific antibody correlates of protection against SARS-CoV-2 Omicron symptomatic and overall infections

针对SARS-CoV-2 Omicron病毒株的变异株特异性抗体与症状性感染和总体感染的保护作用相关

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-65235-8
Zambrana, José Victor; Mellis, Ian A; Shotwell, Abigail; Maier, Hannah E; Saborio, Yara; Barillas, Carlos; Lopez, Roger; Vasquez, Gerald; Plazaola, Miguel; Sanchez, Nery; Ojeda, Sergio; Gilbertson, Isabel; Kuan, Guillermina; Wang, Qian; Liu, Lihong; Balmaseda, Angel; Ho, David D; Gordon, Aubree
炎症/感染
SARS-CoV-2
微生物学
发表日期：2025
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Optimizing a human monoclonal antibody for better neutralization of SARS-CoV-2.

优化人源单克隆抗体以更好地中和 SARS-CoV-2

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-61472-z
Wang Qian, Guo Yicheng, Casner Ryan G, Yu Jian, Nair Manoj S, Ho Jerren, Reddem Eswar R, Mellis Ian A, Wu Madeline, Tzang Chih-Chen, Hong Hsiang, Huang Yaoxing, Shapiro Lawrence, Liu Lihong, Ho David D
炎症/感染
新冠
Human
发表日期：2025
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A Human Immuno-Lung Organoid Model to Study Macrophage-Mediated Lung Cell Senescence Upon SARS-CoV-2 Infection

利用人免疫肺类器官模型研究SARS-CoV-2感染后巨噬细胞介导的肺细胞衰老

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202503932
Han, Yuling; Leng, Dongliang; Zhang, Tuo; Ge, Jian; Fang, Yinshan; Lu, Tiankun; Dong, Xue; Nair, Manoj S; de Silva, Neranjan; Han, Zhaowei; Jiao, Tiancheng; Huang, Yuanhao; Zhao, Meiqi; Saqi, Anjali; Hibshoosh, Hanina; Meng, Zihe; Xiang, Jenny Z; Pan, Chendong; Sun, Yanjie; Ho, David D; Evans, Todd; Liu, Jie; Yang, Liuliu; Que, Jianwen; Chen, Shuibing
巨噬细胞
SARS-CoV-2
炎症/感染
巨噬细胞
Senescence
细胞衰老
Human
衰老
3D/类器官
细胞生物学
免疫/内分泌
发表日期：2025
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Antibody evasion and receptor binding of SARS-CoV-2 LP.8.1.1, NB.1.8.1, XFG, and related subvariants

SARS-CoV-2 LP.8.1.1、NB.1.8.1、XFG 及相关亚型的抗体逃避和受体结合

期刊:Cell Reports
影响因子:6.9
doi:10.1016/j.celrep.2025.116440
Mellis, Ian A; Wu, Madeline; Hong, Hsiang; Tzang, Chih-Chen; Bowen, Anthony; Wang, Qian; Gherasim, Carmen; Pierce, Virginia M; Shah, Jayesh G; Purpura, Lawrence J; Yin, Michael T; Gordon, Aubree; Guo, Yicheng; Ho, David D
信号转导
SARS-CoV-2
发表日期：2025
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Antibody evasiveness of SARS-CoV-2 subvariants KP.3.1.1 and XEC.

SARS-CoV-2 亚型 KP.3.1.1 和 XEC 的抗体逃避能力

期刊:Cell Reports
影响因子:6.9
doi:10.1016/j.celrep.2025.115543
Wang Qian, Guo Yicheng, Mellis Ian A, Wu Madeline, Mohri Hiroshi, Gherasim Carmen, Valdez Riccardo, Purpura Lawrence J, Yin Michael T, Gordon Aubree, Ho David D
炎症/感染
新冠
发表日期：2025
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Persistence of an Infectious Form of SARS-CoV-2 After Protease Inhibitor Treatment of Permissive Cells In Vitro

体外用蛋白酶抑制剂处理易感细胞后，SARS-CoV-2 感染形式的持续存在

期刊:Journal of Infectious Diseases
影响因子:4.5
doi:10.1093/infdis/jiae385
Nair, Manoj S; Luck, Maria I; Huang, Yaoxing; Sabo, Yosef; Ho, David D
炎症/感染
细胞生物学
SARS-CoV-2
发表日期：2025
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