日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The Promises and Prospects of Long-Acting Therapeutics for Treatment and Prevention of Infectious Diseases

长效疗法在传染病治疗和预防中的前景与潜力

Olagunju, Adeniyi; Perazzolo, Simone; Stephen, Zachary R; Ryan, Mark; Xu, Xiaolin; Venkatasubramanian, Prajith; Atoyebi, Shakir; Fratte, Rachele Delle; Owen, Andrew; Flexner, Charles; Ho, Rodney J Y

Accelerating Generic Long-Acting Antiretrovirals for Global HIV Treatment: Workshop Findings and a Roadmap to Access

加速推广通用长效抗逆转录病毒药物以用于全球艾滋病治疗:研讨会成果及获取路线图

Arshad, Usman; Gaayeb, Lobna; Pertinez, Henry; Rajoli, Rajith K R; Watkins, Melynda; Nimbolkar, Parag; Perazzolo, Simone; Pagi, Bharat; Wensing, Annemarie; Khoo, Saye; Boffito, Marta; Holm, René; Panos, Zack; Mahaka, Imelda; Venter, Francois; Kottiri, Benny; Crawford, Keith W; Ho, Rodney J Y; Clayden, Polly; Domanico, Paul; Struble, Kimberly; Owen, Andrew; Flexner, Charles

Long-acting Injectable Containing Lopinavir Eliminates Reliance on Ritonavir Pharmacokinetic Enhancement

含有洛匹那韦的长效注射剂消除了对利托那韦药代动力学增强剂的依赖

Perazzolo, Simone; Flexner, Charles W; Stephen, Zachary R; Acosta, Edward P; Bender Ignacio, Rachel A; Ho, Rodney J Y

Physiologically based Pharmacokinetic Model Validated to Enable Predictions Of Multiple Drugs in a Long-acting Drug-combination Nano-Particles (DcNP): Confirmation with 3 HIV Drugs, Lopinavir, Ritonavir, and Tenofovir in DcNP Products

基于生理的药代动力学模型经验证可用于预测长效药物组合纳米颗粒 (DcNP) 中多种药物的药代动力学:以三种 HIV 药物(洛匹那韦、利托那韦和替诺福韦)在 DcNP 产品中的药代动力学为验证

Perazzolo, Simone; Shen, Danny D; Scott, Ariel M; Ho, Rodney J Y

Inoculation of Pan02 cells produces tumor nodules in mouse pancreas: Characterization of a novel orthotopic pancreatic ductal adenocarcinoma tumor model for interventional studies

Pan02细胞接种于小鼠胰腺可形成肿瘤结节:一种新型原位胰腺导管腺癌肿瘤模型在介入研究中的表征

Griffin, James I; Chen, Xinyue; Duan, Luqi; Mu, Qingxin; Ho, Rodney J Y

Viral dissemination and immune activation modulate antiretroviral drug levels in lymph nodes of SIV-infected rhesus macaques

病毒扩散和免疫激活调节SIV感染恒河猴淋巴结中抗逆转录病毒药物的水平

Srinivasula, Sharat; Degrange, Paula; Perazzolo, Simone; Bonvillain, Andrew; Tobery, Amanda; Kaplan, Jacob; Jang, Hyukjin; Turnier, Refika; Davies, Michael; Cottrell, Mackenzie; Ho, Rodney J Y; Di Mascio, Michele

U.S. patient preferences for long-acting HIV treatment: a discrete choice experiment

美国患者对长效HIV治疗药物的偏好:一项离散选择实验

Graham, Susan M; Barthold, Douglas; Hauber, Brett; Brah, Aaron T; Saldarriaga, Enrique; Collier, Ann C; Ho, Rodney J Y; Marconi, Vincent C; Simoni, Jane M

A novel formulation enabled transformation of 3-HIV drugs tenofovir-lamivudine-dolutegravir from short-acting to long-acting all-in-one injectable

一种新型制剂使得三种抗HIV药物替诺福韦-拉米夫定-多替拉韦从短效制剂转变为长效一体化注射剂。

Perazzolo, Simone; Stephen, Zachary R; Eguchi, Masa; Xu, Xiaolin; Delle Fratte, Rachele; Collier, Ann C; Melvin, Ann J; Ho, Rodney J Y

Challenges and opportunities in metastatic breast cancer treatments: Nano-drug combinations delivered preferentially to metastatic cells may enhance therapeutic response

转移性乳腺癌治疗的挑战与机遇:优先靶向转移细胞的纳米药物组合可能增强治疗反应

Yu, Jesse; Mu, Qingxin; Fung, Millie; Xu, Xiaolin; Zhu, Linxi; Ho, Rodney J Y

Physiologically Based Pharmacokinetic Modeling of 3 HIV Drugs in Combination and the Role of Lymphatic System after Subcutaneous Dosing. Part 1: Model for the Free-Drug Mixture

基于生理的HIV药物联合用药药代动力学模型及其皮下给药后淋巴系统的作用。第一部分:游离药物混合物模型

Perazzolo, Simone; Shireman, Laura M; Shen, Danny D; Ho, Rodney J Y