日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The novel amino-artemisinin derivative WHN-11 disrupts mitochondria and protein homeostasis, and induces autophagy and apoptosis in cancer cells.

新型氨基青蒿素衍生物 WHN-11 可破坏线粒体和蛋白质稳态,并诱导癌细胞自噬和凋亡

Kajewole Deborah, Wong Ho Ning, von Kriegsheim Alexander, Haynes Richard K, de la Mare Jo-Anne, Edkins Adrienne Lesley

Efficacies and ADME properties of redox active methylene blue and phenoxazine analogues for use in new antimalarial triple drug combinations with amino-artemisinins

氧化还原活性亚甲蓝和吩恶嗪类似物与氨基青蒿素在新型抗疟三联药物组合中的功效和 ADME 特性

Daniel J Watson, Lizahn Laing, Jacobus P Petzer, Ho Ning Wong, Christopher J Parkinson, Lubbe Wiesner, Richard K Haynes

Donor Blood Tests do Not Predict Pancreas Graft Survival After Simultaneous Pancreas Kidney Transplantation; a National Cohort Study

供体血液检测无法预测胰肾联合移植术后胰腺移植的存活率:一项全国性队列研究

Ho, Ning Xuan; Tingle, Samuel J; Malik, Abdullah K; Thompson, Emily R; Kourounis, Georgios; Amer, Aimen; Pandanaboyana, Sanjay; Wilson, Colin; White, Steve

Single and combination treatment of Toxoplasma gondii infections with a bumped kinase inhibitor and artemisone in vitro and with artemiside in experimentally infected mice

体外实验中,使用激酶抑制剂和青蒿素单独或联合治疗弓形虫感染;在实验感染小鼠中,使用青蒿素治疗弓形虫感染。

Schlange, Carling; Müller, Joachim; Imhof, Dennis; Hänggeli, Kai Pascal Alexander; Boubaker, Ghalia; Ortega-Mora, Luis-Miguel; Wong, Ho Ning; Haynes, Richard K; Van Voorhis, Wesley C; Hemphill, Andrew

A curious case of metastatic parotid adenoid cystic carcinoma to kidney

一例罕见的腮腺腺样囊性癌肾转移病例

Ho, Ning Xuan; O'Meara, Sorcha; Moran, Tom; McGuire, Barry

The Artemiside-Artemisox-Artemisone-M1 Tetrad: Efficacies against Blood Stage P. falciparum Parasites, DMPK Properties, and the Case for Artemiside

青蒿素-蒿甲醚-蒿甲醚-M1四联疗法:对恶性疟原虫血期寄生虫的疗效、药物代谢动力学特性及青蒿素的应用前景

Gibhard, Liezl; Coertzen, Dina; Reader, Janette; van der Watt, Mariëtte E; Birkholtz, Lyn-Marie; Wong, Ho Ning; Batty, Kevin T; Haynes, Richard K; Wiesner, Lubbe

Toward New Transmission-Blocking Combination Therapies: Pharmacokinetics of 10-Amino-Artemisinins and 11-Aza-Artemisinin and Comparison with Dihydroartemisinin and Artemether

探索新型阻断传播联合疗法:10-氨基青蒿素和11-氮杂青蒿素的药代动力学及其与双氢青蒿素和蒿甲醚的比较

Watson, Daniel J; Laing, Lizahn; Gibhard, Liezl; Wong, Ho Ning; Haynes, Richard K; Wiesner, Lubbe

Optimal 10-Aminoartemisinins With Potent Transmission-Blocking Capabilities for New Artemisinin Combination Therapies-Activities Against Blood Stage P. falciparum Including Pf KI3 C580Y Mutants and Liver Stage P. berghei Parasites

具有强效传播阻断能力的最佳 10 氨基青蒿素,可用于新型青蒿素联合疗法 - 针对血液阶段恶性疟原虫(包括 Pf KI3 C580Y 突变体)和肝脏阶段伯氏疟原虫寄生虫的活性

Ho Ning Wong, Vivian Padín-Irizarry, Mariëtte E van der Watt, Janette Reader, Wilna Liebenberg, Lubbe Wiesner, Peter Smith, Korina Eribez, Elizabeth A Winzeler, Dennis E Kyle, Lyn-Marie Birkholtz, Dina Coertzen, Richard K Haynes

Artemisone and Artemiside Are Potent Panreactive Antimalarial Agents That Also Synergize Redox Imbalance in Plasmodium falciparum Transmissible Gametocyte Stages

青蒿素和蒿甲醚是强效的泛反应性抗疟药,它们还能协同作用,消除恶性疟原虫可传播配子体阶段的氧化还原失衡。

Coertzen, Dina; Reader, Janette; van der Watt, Mariëtte; Nondaba, Sindisiwe H; Gibhard, Liezl; Wiesner, Lubbe; Smith, Peter; D'Alessandro, Sarah; Taramelli, Donatella; Wong, Ho Ning; du Preez, Jan L; Wu, Ronald Wai Keung; Birkholtz, Lyn-Marie; Haynes, Richard K

Correction: Resistin promotes tumor metastasis by down-regulation of miR-519d through the AMPK/p38 signaling pathway in human chondrosarcoma cells

更正:在人软骨肉瘤细胞中,抵抗素通过AMPK/p38信号通路下调miR-519d,从而促进肿瘤转移。

Tsai, Chun-Hao; Tsai, Hsiao-Chi; Huang, Ho-Ning; Hung, Chih-Hung; Hsu, Chin-Jung; Fong, Yi-Chin; Hsu, Horng-Chaung; Huang, Yuan-Li; Tang, Chih-Hsin