日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Genetic modulators of metabolic dysfunction-associated steatotic liver disease (MASLD) and their epistatic interactions: from in vitro and animal models to clinical outcomes

代谢功能障碍相关脂肪肝病(MASLD)的遗传调控因子及其上位性相互作用:从体外和动物模型到临床结果

Arriaga-González, Fernanda G; de Jesús Castañeda-Córdova, Felipe; Díaz-Muñoz, Mauricio; Hoare, Matthew; Adams, David J; Robles-Espinoza, Carla Daniela; Molina-Aguilar, Christian

Somatic loss-of-function mutations in CIDEB reduce hepatic steatosis by increasing lipolysis and fatty acid oxidation.

CIDEB 的体细胞功能丧失突变通过增加脂肪分解和脂肪酸氧化来减少肝脂肪变性

Zeng Qiyu, Patel Satish, Wang Xun, Hsieh Meng-Hsiung, Li Zhijie, Ren Xiongzhao, Wang Jingjing, Kim Dohun, Li Shili, Gu Xinping, Mannino Greg, Maggiore Gianna, Fang Xiangyi, Li Lin, Zhu Min, Wang Mengmeng, Li Boyuan, Bellary Amaey, Lim Koini, Qi Zhetuo, Pushpa Pushpa, Mandour Mandour Omer, Saudek Vladimir, Sharma Tripti, Zhang Yu, Hoxhaj Gerta, Mishra Prashant, Gopal Purva, Campbell Peter, Hoare Matthew, Savage David B, Zhu Hao

Selection for somatic escape variants in SERPINA1 in the liver of patients with alpha-1 antitrypsin deficiency.

在α-1抗胰蛋白酶缺乏症患者的肝脏中,SERPINA1基因的体细胞逃逸变异体被选择

Brzozowska Natalia, Wu Lily Y D, Khodzhaeva Vera, Griffiths William J, Duckworth Adam, Jung Hyunchul, Coorens Tim H H, Hooks Yvette, Chambers Joseph E, Campbell Peter J, Marciniak Stefan J, Hoare Matthew

Publisher Correction: Novel immunotherapeutics against LGR5 to target multiple cancer types

出版商更正:针对LGR5的新型免疫疗法可靶向多种癌症类型

Chen, Hung-Chang; Mueller, Nico; Stott, Katherine; Kapeni, Chrysa; Rivers, Eilidh; Sauer, Carolin M; Beke, Flavio; Walsh, Stephen J; Ashman, Nicola; O'Brien, Louise; Rafati Fard, Amir; Ghodsinia, Arman; Li, Changtai; Joud, Fadwa; Giger, Olivier; Zlobec, Inti; Olan, Ioana; Aitken, Sarah J; Hoare, Matthew; Mair, Richard; Serrao, Eva; Brenton, James D; Garcia-Gimenez, Alicia; Richardson, Simon E; Huntly, Brian; Spring, David R; Skjoedt, Mikkel-Ole; Skjødt, Karsten; de la Roche, Marc; de la Roche, Maike

The clinical value of the hepatic venous pressure gradient in patients undergoing hepatic resection for hepatocellular carcinoma with or without liver cirrhosis

肝静脉压力梯度在接受肝切除术治疗肝细胞癌(伴或不伴肝硬化)患者中的临床价值

Busch, Felix; De Paepe, Katja N; Gibbs, Paul; Allison, Michael; Hoare, Matthew; See, Teik Choon

Correction: Acetyl-CoA metabolism drives epigenome change and contributes to carcinogenesis risk in fatty liver disease

更正:乙酰辅酶A代谢驱动表观基因组改变,并增加脂肪肝疾病的致癌风险。

Assante, Gabriella; Chandrasekaran, Sriram; Ng, Stanley; Tourna, Aikaterini; Chung, Carolina H; Isse, Kowsar A; Banks, Jasmine L; Soffientini, Ugo; Filippi, Celine; Dhawan, Anil; Liu, Mo; Rozen, Steven G; Hoare, Matthew; Campbell, Peter; Ballard, J William O; Turner, Nigel; Morris, Margaret J; Chokshi, Shilpa; Youngson, Neil A

A minority of somatically mutated genes in pre-existing fatty liver disease have prognostic importance in the development of NAFLD

在既往存在的脂肪肝疾病中,少数体细胞突变基因对非酒精性脂肪性肝病(NAFLD)的发生发展具有预后意义。

Mann, Jake P; Hoare, Matthew

Sorafenib is associated with a reduced rate of tumour growth and liver function deterioration in HCV-induced hepatocellular carcinoma

索拉非尼与丙型肝炎病毒(HCV)诱发的肝细胞癌的肿瘤生长速度和肝功能恶化程度降低相关。

Kolamunnage-Dona, Ruwanthi; Berhane, Sarah; Potts, Harry; Williams, Edward H; Tanner, James; Janowitz, Tobias; Hoare, Matthew; Johnson, Philip

Robustness of radiomic features in CT images with different slice thickness, comparing liver tumour and muscle

比较不同层厚CT图像中肝肿瘤和肌肉组织放射组学特征的稳健性

Escudero Sanchez, Lorena; Rundo, Leonardo; Gill, Andrew B; Hoare, Matthew; Mendes Serrao, Eva; Sala, Evis

Breath Biopsy Assessment of Liver Disease Using an Exogenous Volatile Organic Compound-Toward Improved Detection of Liver Impairment

利用外源性挥发性有机化合物进行肝病呼吸活检评估——旨在提高肝损伤的检测率

Ferrandino, Giuseppe; Orf, Isabel; Smith, Rob; Calcagno, Marzia; Thind, Anita Kaur; Debiram-Beecham, Irene; Williams, Megan; Gandelman, Olga; de Saedeleer, Alexandra; Kibble, Graham; Lydon, Anne Marie; Mayhew, Chris A; Allsworth, Max; Boyle, Billy; van der Schee, Marc P; Allison, Michael; Hoare, Matthew; Snowdon, Victoria K