日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

ERG1A K(+) channel increases intracellular calcium concentration through modulation of calsequestrin1 in C(2)C(12) myotubes.

ERG1A K(+) 通道通过调节 C(2)C(12) 肌管中的钙结合蛋白 1 来增加细胞内钙浓度

Hockerman Gregory H, Pratt Evan, Guha Shalini, LaVigne Emily, Whitmore Clayton, Khader Omar, McClure Natalie, Zampieri Sandra, Koran Jennifer, Wang W-H, Pond Amber L

The ERG1A K(+) Channel Is More Abundant in Rectus abdominis Muscle from Cancer Patients Than that from Healthy Humans

与健康人相比,癌症患者腹直肌中的ERG1A K(+)通道含量更高。

Zampieri, Sandra; Sandri, Marco; Cheatwood, Joseph L; Balaraman, Rajesh P; Anderson, Luke B; Cobb, Brittan A; Latour, Chase D; Hockerman, Gregory H; Kern, Helmut; Sartori, Roberta; Ravara, Barbara; Merigliano, Stefano; Da Dalt, Gianfranco; Davie, Judith K; Kohli, Punit; Pond, Amber L

The ERG1a potassium channel increases basal intracellular calcium concentration and calpain activity in skeletal muscle cells.

ERG1a钾通道可增加骨骼肌细胞内基础钙浓度和钙蛋白酶活性

Whitmore Clayton, Pratt Evan P S, Anderson Luke, Bradley Kevin, Latour Sawyer M, Hashmi Mariam N, Urazaev Albert K, Weilbaecher Rod, Davie Judith K, Wang Wen-Horng, Hockerman Gregory H, Pond Amber L

Agonists of the γ-aminobutyric acid type B (GABA(B)) receptor derived from β-hydroxy and β-amino difluoromethyl ketones

源自β-羟基和β-氨基二氟甲基酮的γ-氨基丁酸B型(GABA(B))受体激动剂

Sowaileh, Munia F; Salyer, Amy E; Roy, Kuldeep K; John, Jinu P; Woods, James R; Doerksen, Robert J; Hockerman, Gregory H; Colby, David A

The external gate of the human and Drosophila serotonin transporters requires a basic/acidic amino acid pair for 3,4-methylenedioxymethamphetamine (MDMA) translocation and the induction of substrate efflux.

人类和果蝇血清素转运蛋白的外部闸门需要碱性/酸性氨基酸对才能使 3,4-亚甲二氧基甲基苯丙胺 (MDMA) 易位并诱导底物外排

Sealover Natalie R, Felts Bruce, Kuntz Charles P, Jarrard Rachel E, Hockerman Gregory H, Lamb Patrick W, Barker Eric L, Henry L Keith

Ca2+ influx through L-type Ca2+ channels and Ca2+-induced Ca2+ release regulate cAMP accumulation and Epac1-dependent ERK 1/2 activation in INS-1 cells.

L 型 Ca2+ 通道的 Ca2+ 内流和 Ca2+ 诱导的 Ca2+ 释放调节 INS-1 细胞中 cAMP 的积累和 Epac1 依赖的 ERK 1/2 的激活

Pratt Evan P S, Salyer Amy E, Guerra Marcy L, Hockerman Gregory H

The mERG1a channel modulates skeletal muscle MuRF1, but not MAFbx, expression

mERG1a通道调节骨骼肌MuRF1的表达,但不调节MAFbx的表达。

Pond, Amber L; Nedele, Carrie; Wang, Wen-Horng; Wang, Xun; Walther, Claire; Jaeger, Christine; Bradley, Kevin S; Du, Huahua; Fujita, Naoya; Hockerman, Gregory H; Hannon, Kevin M

Uncoupling of Cav1.2 from Ca(2+)-induced Ca(2+) release and SK channel regulation in pancreatic β-cells

胰岛β细胞中Cav1.2与Ca(2+)诱导的Ca(2+)释放和SK通道调节的解偶联

Wang, Yuchen; Jarrard, Rachel E; Pratt, Evan P S; Guerra, Marcy L; Salyer, Amy E; Lange, Allison M; Soderling, Ian M; Hockerman, Gregory H

Development of a high-throughput screening paradigm for the discovery of small-molecule modulators of adenylyl cyclase: identification of an adenylyl cyclase 2 inhibitor

开发用于发现腺苷酸环化酶小分子调节剂的高通量筛选方法:鉴定腺苷酸环化酶 2 抑制剂

Conley, Jason M; Brand, Cameron S; Bogard, Amy S; Pratt, Evan P S; Xu, Ruqiang; Hockerman, Gregory H; Ostrom, Rennolds S; Dessauer, Carmen W; Watts, Val J

The intracellular II-III loops of Cav1.2 and Cav1.3 uncouple L-type voltage-gated Ca2+ channels from glucagon-like peptide-1 potentiation of insulin secretion in INS-1 cells via displacement from lipid rafts

Cav1.2 和 Cav1.3 的细胞内 II-III 环通过从脂筏上置换 L 型电压门控 Ca2+ 通道,使 L 型电压门控 Ca2+ 通道与胰高血糖素样肽-1 增强 INS-1 细胞胰岛素分泌的作用解偶联。

Jacobo, Sarah Melissa P; Guerra, Marcy L; Jarrard, Rachel E; Przybyla, Julie A; Liu, Guohong; Watts, Val J; Hockerman, Gregory H