Hofferek相关文献与解析，生知库 | 链接生命科学的每一步

Sean Hyslop ，Colby J Hofferek ，Maria V Stegantseva ，Emerald Kan ，Kelli A McCord ，Victor M Alvarez ，Amanda Y Xia ，Jacob P Conarty ，Andreas Wieland ，William H Hudson

B细胞

CD7

CD8

发表日期：2025

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Differentiation of Toxoplasma into latent forms is linked to central carbon metabolism and requires a GID/CTLH-type E3 ubiquitin ligase

弓形虫分化为潜伏型与中心碳代谢有关，并且需要GID/CTLH型E3泛素连接酶。

期刊:

影响因子:

doi:10.1101/2025.07.27.667068

Uboldi, Alessandro D; Khurana, Sachin; Jaywickrama, Amalie A; Lekkala-Lethakula, Sai Prasanna; Simonpietri, Amber; Singh, Karan; Hofferek, Vinzenz; Ruparel, Ushma; Whitehead, Lachlan L; Rogers, Kelly L; Garnham, Alexandra L; Scott, Nichollas; Katris, Nicholas J; McConville, Malcolm J; Komander, David; Cobbold, Simon A; Tonkin, Christopher J

代谢

发表日期：2025

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MLKL deficiency elevates testosterone production in male mice independently of necroptotic functions

MLKL 缺乏可独立于坏死性凋亡功能增加雄性小鼠的睾酮生成

期刊:Cell Death & Disease

影响因子:8.1

doi:10.1038/s41419-024-07242-z

Shene Chiou, Wayne Cawthorne, Thomas Soerianto, Vinzenz Hofferek, Komal M Patel, Sarah E Garnish, Emma C Tovey Crutchfield, Cathrine Hall, Joanne M Hildebrand, Malcolm J McConville, Kate E Lawlor, Edwin D Hawkins #, Andre L Samson #, James M Murphy #3

Multifactoral immune modulation potentiates durable remission in multiple models of aggressive malignancy

多因素免疫调节可增强多种侵袭性恶性肿瘤模型中的持久缓解。

期刊:FASEB Journal

影响因子:4.2

doi:10.1096/fj.202302675R

Halpert, Matthew M; Burns, Briana A; Rosario, Spencer R; Withers, Henry G; Trivedi, Akshar J; Hofferek, Colby J; Gephart, Benjamin D; Wang, Haotong; Vazquez-Perez, Jonathan; Amanya, Sharon B; Hyslop, Sean T; Yang, Jianhua; Kemnade, Jan O; Sandulache, Vlad C; Konduri, Vanaja; Decker, William K

Immunomodulatory proteins from hookworms reduce cardiac inflammation and modulate regulatory responses in a mouse model of chronic Trypanosoma cruzi infection

钩虫的免疫调节蛋白可减轻慢性克氏锥虫感染小鼠模型中的心脏炎症并调节调节反应。

期刊:Frontiers in Parasitology

影响因子:

doi:10.3389/fpara.2023.1244604

Jones, Kathryn M; Zhan, Bin; Ernste, Keenan J; Villar, Maria Jose; Bisht, Nalini; Nguyen, Duc; Chang, Li-Yen; Poveda, Cristina; Robinson, Gonteria J; Trivedi, Akshar J; Hofferek, Colby J; Decker, William K; Konduri, Vanaja

In-cell DNP NMR reveals multiple targeting effect of antimicrobial peptide

细胞内 DNP NMR 揭示抗菌肽的多靶向作用

期刊:Journal of Structural Biology-X

影响因子:3.5

doi:10.1016/j.yjsbx.2022.100074

Frances Separovic, Vinzenz Hofferek, Anthony P Duff, Malcom J McConville, Marc-Antoine Sani

A subset of cytotoxic effector memory T cells enhances CAR T cell efficacy in a model of pancreatic ductal adenocarcinoma

在胰腺导管腺癌模型中，一部分细胞毒性效应记忆T细胞可增强CAR-T细胞的疗效。

期刊:Science Translational Medicine

影响因子:15.8

doi:10.1126/scitranslmed.abc3196

Vanaja Konduri,Sujith K Joseph,Tiara T Byrd,Zeid Nawas,Jonathan Vazquez-Perez,Colby J Hofferek,Matthew M Halpert,Dongliang Liu,Zhengdong Liang,Yunyu Baig,Vita S Salsman,Damilola Oyewole-Said,Anna Tsimelzon,Briana A Burns,Changyi Chen,Jonathan M Levitt,Qizhi Yao,Nabil M Ahmed,Meenakshi Hegde,William K Decker

A randomized, double-blind, placebo-controlled study of daily cannabidiol for the treatment of canine osteoarthritis pain

一项随机、双盲、安慰剂对照研究，旨在评估每日服用大麻二酚治疗犬骨关节炎疼痛的效果。

期刊:Pain

影响因子:5.5

doi:10.1097/j.pain.0000000000001896

Verrico, Chris D; Wesson, Shonda; Konduri, Vanaja; Hofferek, Colby J; Vazquez-Perez, Jonathan; Blair, Emek; Dunner, Kenneth Jr; Salimpour, Pedram; Decker, William K; Halpert, Matthew M

关节炎

发表日期：2020

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MHC class I and II peptide homology regulates the cellular immune response

MHC I类和II类肽的同源性调节细胞免疫反应

期刊:FASEB Journal

影响因子:4.4

doi:10.1096/fj.201903002R

Matthew M Halpert ，Vanaja Konduri ，Dan Liang ，Jonathan Vazquez-Perez ，Colby J Hofferek ，Scott A Weldon ，Yunyu Baig ，Indira Vedula ，Jonathan M Levitt ，William K Decker

Cardiolipin is required for membrane docking of mitochondrial ribosomes and protein synthesis

心磷脂是线粒体核糖体膜对接和蛋白质合成所必需的

期刊:Journal of Cell Science

影响因子:3.3

doi:10.1242/jcs.240374

Richard G Lee, Junjie Gao, Stefan J Siira, Anne-Marie Shearwood, Judith A Ermer, Vinzenz Hofferek, James C Mathews, Minghao Zheng, Gavin E Reid, Oliver Rackham, Aleksandra Filipovska

信号转导

发表日期：2020

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CD7 regulates the persistence of terminally exhausted CD8+ T cells during chronic infection

CD7 调节慢性感染期间终末耗竭的 CD8+ T 细胞的持续存在

Differentiation of Toxoplasma into latent forms is linked to central carbon metabolism and requires a GID/CTLH-type E3 ubiquitin ligase

弓形虫分化为潜伏型与中心碳代谢有关，并且需要GID/CTLH型E3泛素连接酶。

MLKL deficiency elevates testosterone production in male mice independently of necroptotic functions

MLKL 缺乏可独立于坏死性凋亡功能增加雄性小鼠的睾酮生成

Multifactoral immune modulation potentiates durable remission in multiple models of aggressive malignancy

多因素免疫调节可增强多种侵袭性恶性肿瘤模型中的持久缓解。

Immunomodulatory proteins from hookworms reduce cardiac inflammation and modulate regulatory responses in a mouse model of chronic Trypanosoma cruzi infection

钩虫的免疫调节蛋白可减轻慢性克氏锥虫感染小鼠模型中的心脏炎症并调节调节反应。

In-cell DNP NMR reveals multiple targeting effect of antimicrobial peptide

细胞内 DNP NMR 揭示抗菌肽的多靶向作用

A subset of cytotoxic effector memory T cells enhances CAR T cell efficacy in a model of pancreatic ductal adenocarcinoma

在胰腺导管腺癌模型中，一部分细胞毒性效应记忆T细胞可增强CAR-T细胞的疗效。

A randomized, double-blind, placebo-controlled study of daily cannabidiol for the treatment of canine osteoarthritis pain

一项随机、双盲、安慰剂对照研究，旨在评估每日服用大麻二酚治疗犬骨关节炎疼痛的效果。

MHC class I and II peptide homology regulates the cellular immune response

MHC I类和II类肽的同源性调节细胞免疫反应

Cardiolipin is required for membrane docking of mitochondrial ribosomes and protein synthesis

心磷脂是线粒体核糖体膜对接和蛋白质合成所必需的