日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Parenteral Vaccination with a Live Brucella melitensis Mutant Protects against Wild-Type B. melitensis 16M Challenge

注射活的布鲁氏菌突变株疫苗可预防野生型布鲁氏菌16M株的攻击

Yang, Xinghong; Goodwin, Zakia I; Bhagyaraj, Ella; Hoffman, Carol; Pascual, David W

Treatment with a Lactococcus lactis that chromosomally express E. coli cfaI mitigates salivary flow loss in a Sjögren's syndrome-like disease

使用染色体表达大肠杆菌 cfaI 的乳酸乳球菌进行治疗可减轻干燥综合征样疾病的唾液流量减少。

Akgul, Ali; Freguia, Christian Furlan; Maddaloni, Massimo; Hoffman, Carol; Voigt, Alexandria; Nguyen, Cuong Q; Fanger, Neil A; Fanger, Gary R; Pascual, David W

A Single Nasal Dose Vaccination with a Brucella abortus Mutant Potently Protects against Pulmonary Infection

单次鼻内接种布鲁氏菌突变株疫苗可有效预防肺部感染

Wang, Hongbin; Clapp, Beata; Hoffman, Carol; Yang, Xinghong; Pascual, David W

Live mucosal vaccination stimulates potent protection via varied CD4(+) and CD8(+) T cell subsets against wild-type Brucella melitensis 16M challenge

活黏膜疫苗可通过多种 CD4(+) 和 CD8(+) T 细胞亚群刺激产生针对野生型布鲁氏菌 16M 攻击的有效保护作用

Goodwin, Zakia I; Yang, Xinghong; Hoffman, Carol; Pascual, David W

Activation of mucosal immunity as a novel therapeutic strategy for combating brucellosis

激活黏膜免疫作为对抗布鲁氏菌病的新型治疗策略

Pascual, David W; Goodwin, Zakia I; Bhagyaraj, Ella; Hoffman, Carol; Yang, Xinghong

Antigen-encapsulating host extracellular vesicles derived from Salmonella-infected cells stimulate pathogen-specific Th1-type responses in vivo

源自沙门氏菌感染细胞的抗原包裹宿主细胞外囊泡可在体内刺激病原体特异性Th1型免疫应答。

Hui, Winnie W; Emerson, Lisa E; Clapp, Beata; Sheppe, Austin E; Sharma, Jatin; Del Castillo, Johanna; Ou, Mark; Maegawa, Gustavo H B; Hoffman, Carol; Larkin Iii, Joseph; Pascual, David W; Ferraro, Mariola J

Stimulation of regulatory T cells with Lactococcus lactis expressing enterotoxigenic E. coli colonization factor antigen 1 retains salivary flow in a genetic model of Sjögren's syndrome.

在干燥综合征的遗传模型中,用表达肠毒素大肠杆菌定植因子抗原 1 的乳酸乳球菌刺激调节性 T 细胞可维持唾液流量

Akgul Ali, Maddaloni Massimo, Jun Sang Mu, Nelson Andrew S, Odreman Vanessa Aguilera, Hoffman Carol, Bhagyaraj Ella, Voigt Alexandria, Abbott Jeffrey R, Nguyen Cuong Q, Pascual David W

Targeting resident memory T cell immunity culminates in pulmonary and systemic protection against Brucella infection

靶向激活驻留记忆T细胞免疫最终可实现对布鲁氏菌感染的肺部和全身保护。

Wang, Hongbin; Hoffman, Carol; Yang, Xinghong; Clapp, Beata; Pascual, David W

Caspase-8 Collaborates with Caspase-11 to Drive Tissue Damage and Execution of Endotoxic Shock

Caspase-8 与 Caspase-11 协同作用,导致组织损伤和内毒素休克

Pratyusha Mandal, Yanjun Feng, John D Lyons, Scott B Berger, Shunsuke Otani, Alexandra DeLaney, Gregory K Tharp, Kristal Maner-Smith, Eileen M Burd, Michelle Schaeffer, Sandra Hoffman, Carol Capriotti, Linda Roback, Cedrick B Young, Zhe Liang, Eric A Ortlund, Nelson C DiPaolo, Steven Bosinger, John

Delivery of IL-35 by Lactococcus lactis Ameliorates Collagen-Induced Arthritis in Mice

乳酸乳球菌递送IL-35可改善小鼠胶原诱导性关节炎

Maddaloni, Massimo; Kochetkova, Irina; Hoffman, Carol; Pascual, David W