日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Pharmacokinetic properties of the temozolomide perillyl alcohol conjugate (NEO212) in mice

替莫唑胺紫苏醇缀合物(NEO212)在小鼠体内的药代动力学特性

Cho, Hee-Yeon; Swenson, Steve; Thein, Thu Zan; Wang, Weijun; Wijeratne, Neloni R; Marín-Ramos, Nagore I; Katz, Jonathan E; Hofman, Florence M; Schönthal, Axel H; Chen, Thomas C

NEO212 Inhibits Migration and Invasion of Glioma Stem Cells

NEO212抑制胶质瘤干细胞的迁移和侵袭

Marín-Ramos, Nagore I; Thein, Thu Zan; Cho, Hee-Yeon; Swenson, Stephen D; Wang, Weijun; Schönthal, Axel H; Chen, Thomas C; Hofman, Florence M

Therapeutic Immunization against Glioblastoma

针对胶质母细胞瘤的治疗性免疫

Schijns, Virgil E J C; Pretto, Chrystel; Strik, Anna M; Gloudemans-Rijkers, Rianne; Deviller, Laurent; Pierre, Denis; Chung, Jinah; Dandekar, Manisha; Carrillo, Jose A; Kong, Xiao-Tang; Fu, Beverly D; Hsu, Frank P K; Hofman, Florence M; Chen, Thomas C; Zidovetzki, Raphael; Bota, Daniela A; Stathopoulos, Apostolos

Induction of Pro-Apoptotic Endoplasmic Reticulum Stress in Multiple Myeloma Cells by NEO214, Perillyl Alcohol Conjugated to Rolipram.

NEO214(与罗利普兰偶联的过氧苯甲醇)诱导多发性骨髓瘤细胞发生促凋亡的内质网应激

Chen Thomas C, Chan Nymph, Labib Shirin, Yu Jiali, Cho Hee-Yeon, Hofman Florence M, Schönthal Axel H

NEO212: sub-cytotoxic doses capable of inhibiting glioma stem cell invasion

NEO212:亚细胞毒性剂量,能够抑制胶质瘤干细胞侵袭

Marín-Ramos, Nagore I; Hofman, Florence M; Chen, Thomas C

Phase II study of ERC1671 plus bevacizumab versus bevacizumab plus placebo in recurrent glioblastoma: interim results and correlations with CD4(+) T-lymphocyte counts

ERC1671联合贝伐单抗对比贝伐单抗联合安慰剂治疗复发性胶质母细胞瘤的II期研究:中期结果及与CD4(+) T淋巴细胞计数的相关性

Bota, Daniela A; Chung, Jinah; Dandekar, Manisha; Carrillo, Jose A; Kong, Xiao-Tang; Fu, Beverly D; Hsu, Frank Pk; Schönthal, Axel H; Hofman, Florence M; Chen, Thomas C; Zidovetzki, Raphael; Pretto, Chrystel; Strik, Ankie; Schijns, Virgil Ejc; Stathopoulos, Apostolos

NEO412: A temozolomide analog with transdermal activity in melanoma in vitro and in vivo

NEO412:一种替莫唑胺类似物,在体外和体内均具有经皮治疗黑色素瘤的活性。

Swenson, Steve; Silva-Hirschberg, Catalina; Wang, Weijun; Singh, Anupam; Hofman, Florence M; Chen, Kristen L; Schönthal, Axel H; Chen, Thomas C

First clinical results of a personalized immunotherapeutic vaccine against recurrent, incompletely resected, treatment-resistant glioblastoma multiforme (GBM) tumors, based on combined allo- and auto-immune tumor reactivity

基于同种异体和自身免疫肿瘤反应性的个性化免疫治疗疫苗,用于治疗复发性、不完全切除的、难治性胶质母细胞瘤(GBM)肿瘤,其首批临床结果已公布。

Schijns, Virgil E J C; Pretto, Chrystel; Devillers, Laurent; Pierre, Denis; Hofman, Florence M; Chen, Thomas C; Mespouille, Pascal; Hantos, Peter; Glorieux, Philippe; Bota, Daniela A; Stathopoulos, Apostolos

Development of immune memory to glial brain tumors after tumor regression induced by immunotherapeutic Toll-like receptor 7/8 activation

免疫治疗激活 Toll 样受体 7/8 后,神经胶质脑肿瘤消退,并形成免疫记忆。

Stathopoulos, Apostolis; Pretto, Chrystel; Devillers, Laurent; Pierre, Denis; Hofman, Florence M; Kruse, Carol; Jadus, Martin; Chen, Thomas C; Schijns, Virgil E J C

Exploring the Therapeutic Efficacy of Glioma Vaccines Based on Allo- and Syngeneic Antigens and Distinct Immunological Costimulation Activators

探索基于同种异体和同基因抗原以及不同免疫共刺激激活剂的胶质瘤疫苗的治疗效果

Stathopoulos, Apostolos; Pretto, Chrystel; Devillers, Laurent; Pierre, Denis; Hofman, Florence M; Epstein, Alan L; Farghadani, Hooman; Kruse, Carol A; Jadus, Martin R; Chen, Thomas C; Schijns, Virgil E J C