文献库，生知库 | 链接生命科学的每一步

日期影响因子

Widespread false negatives in DNA-encoded library data: how linker effects impair machine learning-based lead prediction

DNA编码文库数据中普遍存在的假阴性：连接子效应如何损害基于机器学习的先导化合物预测

期刊:Chemical Science

影响因子:7.4

doi:10.1039/d5sc00844a

Montoya, Alba L; Hogendorf, Adam S; Tingey, Steven; Kuberan, Aadarsh; Yuen, Lik Hang; Schüler, Herwig; Franzini, Raphael M

发表日期：2025

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Design and Synthesis of New Quinazolin-4-one Derivatives with Negative mGlu(7) Receptor Modulation Activity and Antipsychotic-Like Properties.

设计和合成具有负 mGlu(7) 受体调节活性和抗精神病样特性的新型喹唑啉-4-酮衍生物

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms24031981

Kaczorowska Katarzyna, Stankiewicz Anna, Bugno Ryszard, Paluchowska Maria H, Burnat Grzegorz, BraÅski Piotr, CieÅlik Paulina, WieroÅska Joanna M, Milik Mariusz, Nowak Mateusz, PrzybyÅowicz Agnieszka, KozioÅ Aneta, Hogendorf Agata, Hogendorf Adam S, Kalinowska-TÅuÅcik Justyna, DuszyÅska Beata, Pilc Andrzej, Bojarski Andrzej J

发表日期：2023

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N-Skatyltryptamines-Dual 5-HT6R/D2R Ligands with Antipsychotic and Procognitive Potential

具有抗精神病和促认知潜力的 N-Skatyltryptamines-双 5-HT6R/D2R 配体

期刊:Molecules

影响因子:4.2

doi:10.3390/molecules26154605

Agata Hogendorf, Adam S Hogendorf, Rafał Kurczab, Grzegorz Satała, Bernadeta Szewczyk, Paulina Cieślik, Gniewomir Latacz, Jadwiga Handzlik, Tomasz Lenda, Katarzyna Kaczorowska, Jakub Staroń, Ryszard Bugno, Beata Duszyńska, Andrzej J Bojarski

发表日期：2021

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Search for a 5-CT alternative. In vitro and in vivo evaluation of novel pharmacological tools: 3-(1-alkyl-1H-imidazol-5-yl)-1H-indole-5-carboxamides, low-basicity 5-HT(7) receptor agonists

寻找 5-CT 的替代品。新型药理学工具的体外和体内评价：3-(1-烷基-1H-咪唑-5-基)-1H-吲哚-5-甲酰胺类化合物，低碱性 5-HT(7) 受体激动剂

期刊:Medchemcomm

doi:10.1039/c8md00313k

Latacz, Gniewomir; Hogendorf, Adam S; Hogendorf, Agata; Lubelska, Annamaria; Wierońska, Joanna M; Woźniak, Monika; Cieślik, Paulina; Kieć-Kononowicz, Katarzyna; Handzlik, Jadwiga; Bojarski, Andrzej J

发表日期：2018

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