日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Viral DNA polymerase structures reveal mechanisms of antiviral drug resistance.

病毒DNA聚合酶结构揭示了抗病毒药物耐药机制

Shankar Sundaresh, Pan Junhua, Yang Pan, Bian Yuemin, Oroszlán Gábor, Yu Zishuo, Mukherjee Purba, Filman David J, Hogle James M, Shekhar Mrinal, Coen Donald M, Abraham Jonathan

Real-Time Imaging of Polioviral RNA Translocation across a Membrane

脊髓灰质炎病毒RNA跨膜转运的实时成像

Karunatilaka, Krishanthi S; Filman, David J; Strauss, Mike; Loparo, Joseph J; Hogle, James M

Cryo-EM structures reveal two distinct conformational states in a picornavirus cell entry intermediate

冷冻电镜结构揭示了小核糖核酸病毒细胞进入中间体的两种不同的构象状态

Shah, Pranav N M; Filman, David J; Karunatilaka, Krishanthi S; Hesketh, Emma L; Groppelli, Elisabetta; Strauss, Mike; Hogle, James M

Covalently circularized nanodiscs for studying membrane proteins and viral entry

用于研究膜蛋白和病毒入侵的共价环化纳米盘

Nasr, Mahmoud L; Baptista, Diego; Strauss, Mike; Sun, Zhen-Yu J; Grigoriu, Simina; Huser, Sonja; Plückthun, Andreas; Hagn, Franz; Walz, Thomas; Hogle, James M; Wagner, Gerhard

Picornavirus RNA is protected from cleavage by ribonuclease during virion uncoating and transfer across cellular and model membranes

小核糖核酸病毒RNA在病毒脱壳和穿过细胞膜及模型膜的过程中,受到保护免受核糖核酸酶的切割。

Groppelli, Elisabetta; Levy, Hazel C; Sun, Eileen; Strauss, Mike; Nicol, Clare; Gold, Sarah; Zhuang, Xiaowei; Tuthill, Tobias J; Hogle, James M; Rowlands, David J

Getting to and through the inner nuclear membrane during herpesvirus nuclear egress

疱疹病毒核输出过程中到达并穿过核内膜的过程

Lye, Ming F; Wilkie, Adrian R; Filman, David J; Hogle, James M; Coen, Donald M

Cryo-electron Microscopy Structures of Expanded Poliovirus with VHHs Sample the Conformational Repertoire of the Expanded State

利用冷冻电镜技术解析含有VHH的扩增型脊髓灰质炎病毒的结构,揭示了扩增态的构象多样性

Strauss, Mike; Schotte, Lise; Karunatilaka, Krishanthi S; Filman, David J; Hogle, James M

Five of Five VHHs Neutralizing Poliovirus Bind the Receptor-Binding Site

五种中和脊髓灰质炎病毒的VHH均能结合受体结合位点

Strauss, Mike; Schotte, Lise; Thys, Bert; Filman, David J; Hogle, James M

Characterization of Poliovirus Neutralization Escape Mutants of Single-Domain Antibody Fragments (VHHs)

单域抗体片段(VHH)脊髓灰质炎病毒中和逃逸突变体的特征分析

Schotte, Lise; Thys, Bert; Strauss, Mike; Filman, David J; Rombaut, Bart; Hogle, James M

Human cytomegalovirus UL97 phosphorylates the viral nuclear egress complex

人巨细胞病毒UL97磷酸化病毒核输出复合物。

Sharma, Mayuri; Bender, Brian J; Kamil, Jeremy P; Lye, Ming F; Pesola, Jean M; Reim, Natalia I; Hogle, James M; Coen, Donald M