日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

APE1 active site residue Asn174 stabilizes the AP site and is essential for catalysis

APE1活性位点残基Asn174稳定AP位点,对催化至关重要。

DeHart, Kaitlin M; Hoitsma, Nicole M; Thompson, Spencer H; Borin, Veniamin A; Agarwal, Pratul K; Freudenthal, Bret D

APE1 active site residue Asn174 stabilizes the AP-site and is essential for catalysis

APE1活性位点残基Asn174稳定AP位点,对催化至关重要。

DeHart, Kaitlin M; Hoitsma, Nicole M; Thompson, Spencer H; Borin, Veniamin A; Agarwal, Pratul K; Freudenthal, Bret D

Mechanistic insight into AP-endonuclease 1 cleavage of abasic sites at stalled replication fork mimics.

对 AP 核酸内切酶 1 切割停滞复制叉模拟物中无碱基位点的机制的深入了解

Hoitsma Nicole M, Norris Jessica, Khoang Thu H, Kaushik Vikas, Chadda Rahul, Antony Edwin, Hedglin Mark, Freudenthal Bret D

Structural basis for APE1 processing DNA damage in the nucleosome

APE1在核小体中处理DNA损伤的结构基础

Weaver, Tyler M; Hoitsma, Nicole M; Spencer, Jonah J; Gakhar, Lokesh; Schnicker, Nicholas J; Freudenthal, Bret D

AP-endonuclease 1 sculpts DNA through an anchoring tyrosine residue on the DNA intercalating loop

AP内切酶1通过DNA嵌入环上的锚定酪氨酸残基来重塑DNA。

Hoitsma, Nicole M; Whitaker, Amy M; Beckwitt, Emily C; Jang, Sunbok; Agarwal, Pratul K; Van Houten, Bennett; Freudenthal, Bret D