日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

DeepMVP: deep learning models trained on high-quality data accurately predict PTM sites and variant-induced alterations

DeepMVP：基于高质量数据训练的深度学习模型能够准确预测PTM位点和变异引起的改变

期刊:Nature Methods
影响因子:32.1
doi:10.1038/s41592-025-02797-x
Wen, Bo; Wang, Chenwei; Li, Kai; Han, Ping; Holt, Matthew V; Savage, Sara R; Lei, Jonathan T; Dou, Yongchao; Shi, Zhiao; Li, Yi; Zhang, Bing
发表日期：2025
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COOKIE-Pro: covalent inhibitor binding kinetics profiling on the proteome scale.

COOKIE-Pro：蛋白质组规模的共价抑制剂结合动力学分析。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-63491-2
Lin Hanfeng, Yang Bin, Ding Lang, Yang Yen-Yu, Holt Matthew V, Jung Sung Yun, Zhang Bing, Wang Meng C, Wang Jin
发表日期：2025
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Proteogenomic analysis of the CALGB 40601 (Alliance) HER2+ breast cancer neoadjuvant trial reveals resistance biomarkers.

CALGB 40601（Alliance）HER2+乳腺癌新辅助治疗试验的蛋白质基因组学分析揭示了耐药生物标志物

期刊:Cell Reports Medicine
影响因子:10.6
doi:10.1016/j.xcrm.2025.102154
Jaehnig Eric J, Fernandez-Martinez Aranzazu, Vashist Tanmayi D, Holt Matthew V, Williams LaTerrica, Lei Jonathan T, Moon Chang In, Kim Beom-Jun, Dou Yongchao, Zhao Haoquan, Korchina Viktoriya, Gibbs Richard A, Muzny Donna Marie, Doddapaneni Harshavardhan, Perou Charles M, Carey Lisa A, Robles Ana I, Hyslop Terry, Wen Yujia, McCart Linda, Krek Azra, Petralia Francesca, Miles George, Kavuri Shyam M, Gillette Michael A, Mani D R, Carr Steven A, Zhang Bing, Ellis Matthew J, Satpathy Shankha, Anurag Meenakshi
肿瘤
乳腺癌
肿瘤免疫
发表日期：2025
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COOKIE-Pro: Covalent Inhibitor Binding Kinetics Profiling on the Proteome Scale.

COOKIE-Pro：蛋白质组规模的共价抑制剂结合动力学分析

期刊:
影响因子:
doi:10.1101/2025.06.19.660637
Lin Hanfeng, Yang Bin, Ding Lang, Yang Yen-Yu, Holt Matthew V, Jung Sung Yun, Zhang Bing, Wang Meng C, Wang Jin
其它
发表日期：2025
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Kinase inhibitor pulldown assay (KiP) for clinical proteomics

激酶抑制剂下拉分析（KiP）用于临床蛋白质组学

期刊:Clinical Proteomics
影响因子:3.3
doi:10.1186/s12014-023-09448-3
Saltzman, Alexander B; Chan, Doug W; Holt, Matthew V; Wang, Junkai; Jaehnig, Eric J; Anurag, Meenakshi; Singh, Purba; Malovannaya, Anna; Kim, Beom-Jun; Ellis, Matthew J
信号转导
发表日期：2024
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The Breast Cancer Proteome and Precision Oncology

乳腺癌蛋白质组学与精准肿瘤学

期刊:Cold Spring Harbor Perspectives in Medicine
影响因子:10.1
doi:10.1101/cshperspect.a041323
Lei, Jonathan T; Jaehnig, Eric J; Smith, Hannah; Holt, Matthew V; Li, Xi; Anurag, Meenakshi; Ellis, Matthew J; Mills, Gordon B; Zhang, Bing; Labrie, Marilyne
肿瘤
肿瘤免疫
乳腺癌
发表日期：2023
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Proteogenomic Approaches for the Identification of NF1/Neurofibromin-depleted Estrogen Receptor-positive Breast Cancers for Targeted Treatment

利用蛋白质基因组学方法鉴定NF1/神经纤维蛋白缺失的雌激素受体阳性乳腺癌，以进行靶向治疗

期刊:Cancer Research Communications
影响因子:3.3
doi:10.1158/2767-9764.CRC-23-0044
Kim, Beom-Jun; Zheng, Ze-Yi; Lei, Jonathan T; Holt, Matthew V; Chen, Anran; Peng, Jianheng; Fandino, Diana; Singh, Purba; Kennedy, Hilda; Dou, Yongchao; Chica-Parrado, María Del Rosario; Bikorimana, Emmanuel; Ye, Dan; Wang, Yunguan; Hanker, Ariella B; Mohamed, Nada; Hilsenbeck, Susan G; Lim, Bora; Asirvatham, Jaya Ruth; Sreekumar, Arun; Zhang, Bing; Miles, George; Anurag, Meenakshi; Ellis, Matthew J; Chang, Eric C
肿瘤
肿瘤免疫
信号转导
NF1
乳腺癌
免疫/内分泌
发表日期：2023
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Kinase Inhibitor Pulldown Assay Identifies a Chemotherapy Response Signature in Triple-negative Breast Cancer Based on Purine-binding Proteins

基于嘌呤结合蛋白的激酶抑制剂下拉实验鉴定出三阴性乳腺癌的化疗反应特征

期刊:Cancer Research Communications
影响因子:3.3
doi:10.1158/2767-9764.CRC-22-0501
Wang, Junkai; Saltzman, Alexander B; Jaehnig, Eric J; Lei, Jonathan T; Malovannaya, Anna; Holt, Matthew V; Young, Meggie N; Rimawi, Mothaffar F; Ademuyiwa, Foluso O; Anurag, Meenakshi; Kim, Beom-Jun; Ellis, Matthew J
信号转导
肿瘤
肿瘤免疫
乳腺癌
发表日期：2023
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The histone H3.3 chaperone HIRA restrains erythroid-biased differentiation of adult hematopoietic stem cells

组蛋白H3.3分子伴侣HIRA抑制成体造血干细胞向红系分化

期刊:Stem Cell Reports
影响因子:5.1
doi:10.1016/j.stemcr.2021.06.009
Murdaugh, Rebecca L; Hoegenauer, Kevin A; Kitano, Ayumi; Holt, Matthew V; Hill, Matthew C; Shi, Xiangguo; Tiessen, Jonathan F; Chapple, Richard; Hu, Tianyuan; Tseng, Yu-Jung; Lin, Angelique; Martin, James F; Young, Nicolas L; Nakada, Daisuke
细胞生物学
发育与干细胞
干细胞
发表日期：2021
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Discovery of small molecules targeting the tandem tudor domain of the epigenetic factor UHRF1 using fragment-based ligand discovery.

利用基于片段的配体发现方法，发现靶向表观遗传因子 UHRF1 的串联 Tudor 结构域的小分子

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-020-80588-4
Chang Lyra, Campbell James, Raji Idris O, Guduru Shiva K R, Kandel Prasanna, Nguyen Michelle, Liu Steven, Tran Kevin, Venugopal Navneet K, Taylor Bethany C, Holt Matthew V, Young Nicolas L, Samuel Errol L G, Jain Prashi, Santini Conrad, Sankaran Banumathi, MacKenzie Kevin R, Young Damian W
表观遗传
发表日期：2021
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