日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

RLS-0071, a novel anti-inflammatory agent, significantly reduced inflammatory biomarkers in a randomised human evaluation of mechanisms and safety study

新型抗炎药物 RLS-0071 在一项随机人体机制和安全性评估研究中显著降低了炎症生物标志物。

Cunnion, Kenji; Goss, Jessica; Hair, Pamela; Dell, Linda; Roberson, Destrey; Thienel, Ulrich; Müller, Meike; Carstensen-Aurèche, Saskia; Badorrek, Philipp; Holz, Olaf; Hohlfeld, Jens M

Exhaled breath particles as a novel tool to study lipid composition of epithelial lining fluid from the distal lung

呼出气体颗粒作为研究远端肺上皮衬液脂质组成的新工具

Larsson, Per; Holz, Olaf; Koster, Grielof; Postle, Anthony; Olin, Anna-Carin; Hohlfeld, Jens M

Inflammatory cytokines can be monitored in exhaled breath particles following segmental and inhalation endotoxin challenge in healthy volunteers

在健康志愿者中,通过节段性或吸入性内毒素激发试验,可以监测呼出气体颗粒中的炎症细胞因子。

Holz, Olaf; Müller, Meike; Carstensen, Saskia; Olin, Anna-Carin; Hohlfeld, Jens M

3D-printed mouthpiece adapter for sampling exhaled breath in medical applications

用于医疗应用中呼出气体采样的3D打印吹嘴适配器

Pham, Y Lan; Beauchamp, Jonathan; Clement, Alexander; Wiegandt, Felix; Holz, Olaf

Cross-sectional Study of Workers Employed at a Copper Smelter-Effects of Long-term Exposures to Copper on Lung Function and Chronic Inflammation

一项针对铜冶炼厂工人的横断面研究——长期接触铜对肺功能和慢性炎症的影响

Haase, Lisa-Marie; Birk, Thomas; Poland, Craig A; Holz, Olaf; Müller, Meike; Bachand, Annette M; Mundt, Kenneth A

Breath volatile organic compounds and inflammatory markers in adult asthma patients: negative results from the ALLIANCE cohort

成人哮喘患者呼出气挥发性有机化合物和炎症标志物:ALLIANCE队列研究的阴性结果

Holz, Olaf; Waschki, Benjamin; Watz, Henrik; Kirsten, Anne; Abdo, Mustafa; Pedersen, Frauke; Weckmann, Markus; Fuchs, Oliver; Dittrich, Anna-Maria; Hansen, Gesine; Kopp, Matthias V; von Mutius, Erika; Rabe, Klaus F; Hohlfeld, Jens M; Bahmer, Thomas

Raised sputum extracellular DNA confers lung function impairment and poor symptom control in an exacerbation-susceptible phenotype of neutrophilic asthma

中性粒细胞性哮喘急性发作易感表型患者的痰液细胞外DNA升高会导致肺功能受损和症状控制不佳。

Abdo, Mustafa; Uddin, Mohib; Goldmann, Torsten; Marwitz, Sebastian; Bahmer, Thomas; Holz, Olaf; Kirsten, Anne-Marie; Trinkmann, Frederik; von Mutius, Erika; Kopp, Matthias; Hansen, Gesine; Rabe, Klaus F; Watz, Henrik; Pedersen, Frauke

Influence of Cell Quality on Inflammatory Biomarkers in COPD Sputum Supernatant

细胞质量对慢性阻塞性肺疾病痰液上清液中炎症生物标志物的影响

Pedersen, Frauke; Trinkmann, Frederik; Abdo, Mustafa; Kirsten, Anne-Marie; Rabe, Klaus F; Watz, Henrik; Baraldo, Simonetta; Saetta, Marina; Hohlfeld, Jens M; Holz, Olaf

Protocol for an observational study to identify potential predictors of an acute exacerbation in patients with chronic obstructive pulmonary disease (the PACE Study)

一项观察性研究方案,旨在识别慢性阻塞性肺疾病患者急性加重的潜在预测因素(PACE 研究)

Kenn, Klaus; Gloeckl, Rainer; Leitl, Daniela; Schneeberger, Tessa; Jarosch, Inga; Hitzl, Wolfgang; Alter, Peter; Sczepanski, Bernd; Winterkamp, Sandra; Boensch, Martina; Schade-Brittinger, Carmen; Skevaki, Chrysanthi; Holz, Olaf; Jones, Paul W; Vogelmeier, Claus F; Koczulla, Andreas R

Ultrafine particles and ozone perturb norepinephrine clearance rather than centrally generated sympathetic activity in humans

超细颗粒物和臭氧会干扰人体去甲肾上腺素的清除,而不是中枢产生的交感神经活动。

Heusser, Karsten; Tank, Jens; Holz, Olaf; May, Marcus; Brinkmann, Julia; Engeli, Stefan; Diedrich, André; Framke, Theodor; Koch, Armin; Großhennig, Anika; Jan Danser, A H; Sweep, Fred C G J; Schindler, Christoph; Schwarz, Katharina; Krug, Norbert; Jordan, Jens; Hohlfeld, Jens M