日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

MCT1 Modulates Cancer Cell Pyruvate Export and Growth of Tumors that Co-express MCT1 and MCT4

MCT1 调节共表达 MCT1 和 MCT4 的癌细胞的丙酮酸输出和肿瘤生长

Hong, Candice Sun; Graham, Nicholas A; Gu, Wen; Espindola Camacho, Carolina; Mah, Vei; Maresh, Erin L; Alavi, Mohammed; Bagryanova, Lora; Krotee, Pascal A L; Gardner, Brian K; Behbahan, Iman Saramipoor; Horvath, Steve; Chia, David; Mellinghoff, Ingo K; Hurvitz, Sara A; Dubinett, Steven M; Critchlow, Susan E; Kurdistani, Siavash K; Goodglick, Lee; Braas, Daniel; Graeber, Thomas G; Christofk, Heather R

Dichloroacetate should be considered with platinum-based chemotherapy in hypoxic tumors rather than as a single agent in advanced non-small cell lung cancer.

对于乏氧肿瘤,应考虑将二氯乙酸与铂类化疗联合使用,而不是作为晚期非小细胞肺癌的单一药物

Garon Edward B, Christofk Heather R, Hosmer Wylie, Britten Carolyn D, Bahng Agnes, Crabtree Matthew J, Hong Candice Sun, Kamranpour Naeimeh, Pitts Sharon, Kabbinavar Fairooz, Patel Cecil, von Euw Erika, Black Alexander, Michelakis Evangelos D, Dubinett Steven M, Slamon Dennis J