日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Identification of 4,5,6,7-Tetrabromo-1H-benzotriazole (TBB) as a Small Molecule MESH1 Inhibitor that Suppresses Ferroptosis

鉴定出4,5,6,7-四溴-1H-苯并三唑(TBB)是一种小分子MESH1抑制剂,可抑制铁死亡

Mestre, Alexander A; Oh, Yunju; Wu, Jianli; Dunn, Denise; Setayeshpour, Yasaman; Chen, Ssu-Yu; Lin, Chao-Chieh; Cochrane, C Skyler; Jeong, Pyeonghwa; Nam, Gibeom; Markey, Chloe; Reker, Daniel; Floyd, Scott R; Hong, Jiyong; Zhou, Pei; Chi, Jen-Tsan

Asymmetric Total Synthesis of 4,9,10-Trihydroxyguaia-11(13)en-12,6-olide and Discovery of Its Anticancer Activity against Atypical Teratoid Rhabdoid Tumor

4,9,10-三羟基愈创木-11(13)烯-12,6-内酯的不对称全合成及其对非典型畸胎瘤样横纹肌瘤的抗癌活性发现

Lee, Hyejin; Jang, Hongjun; Myung, Hwan; Rivera, Angela; Averette, Anna F; Heitman, Joseph; Park, Jiyong; Kim, Deukjoon; Kim, Hyoungsu; Hong, Jiyong

Asymmetric Synthesis of the TRPV1 Modulator AMG8562 via Lipase-Catalyzed Kinetic Resolution

利用脂肪酶催化动力学拆分法不对称合成TRPV1调节剂AMG8562

Wang, Eric C; Jeong, Pyeonghwa; Han, Chris; Oh, Yunju; Zhao, Yiquan; Hong, Jiyong

From Obscurity to Opportunity: LpxH Emerges as a Promising Antibiotic Target in the Battle against Gram-Negative Pathogens

从默默无闻到迎来机遇:LpxH 成为对抗革兰氏阴性病原体的潜在抗生素靶点

Dome, Patrick A; Cochrane, C Skyler; Switzer, Hannah J; Lee, Hyejin; Jeong, Pyeonghwa; Hong, Jiyong; Zhou, Pei

REV1 Loss Triggers a G2/M Cell-Cycle Arrest Through Dysregulation of Mitotic Regulators

REV1缺失通过有丝分裂调节因子的失调引发G2/M期细胞周期阻滞

Buntin, Brailey; Guyette, Madison; Gupta, Vihit; Ikeh, Kanayo; Bhattacharya, Sombodhi; Lamkin, Erica N; Lafuze, Allison; Del Rio-Guerra, Roxana; Hong, Jiyong; Zhou, Pei; Chatterjee, Nimrat

REV1 inhibition enhances trinucleotide repeat mutagenesis

REV1抑制增强三核苷酸重复序列突变

Siegel, Ava; Almstead, Daniel; Kothandaraman, Naveen; Reich, Jessica; Lamkin, Erica; Victor, Josh A; Grover, Aarzoo; Ikeh, Kanayo; Koval, Hannah; Crompton, Andrew; Jang, Hongjun; Lee, Hyejin; Del Rio Guerra, Roxana; Korzhnev, Dmitry M; Kyle Hadden, M; Hong, Jiyong; Zhou, Pei; Chatterjee, Nimrat

A one-step protocol to generate impermeable fluorescent HaloTag substrates for in situ live cell application and super-resolution imaging

一种一步法制备不透水荧光HaloTag底物的方法,适用于原位活细胞应用和超分辨率成像。

Roßmann, Kilian; Sun, Siqi; Olesen, Christina Holmboe; Kowald, Maria; Tapp, Eleni; Pabst, Ulrich; Bieck, Marie; Birke, Ramona; Shields, Brenda C; Jeong, PyeongHwa; Hong, Jiyong; Tadross, Michael R; Levitz, Joshua; Lehmann, Martin; Lipstein, Noa; Broichhagen, Johannes

Roles of trans-lesion synthesis (TLS) DNA polymerases in tumorigenesis and cancer therapy

跨损伤合成(TLS)DNA聚合酶在肿瘤发生和癌症治疗中的作用

Anand, Jay; Chiou, Lilly; Sciandra, Carly; Zhang, Xingyuan; Hong, Jiyong; Wu, Di; Zhou, Pei; Vaziri, Cyrus

Psymberin, a marine-derived natural product, induces cancer cell growth arrest and protein translation inhibition

Psymberin是一种海洋来源的天然产物,可诱导癌细胞生长停滞和蛋白质翻译抑制。

Dayanidhi, Divya L; Somarelli, Jason A; Mantyh, John B; Rupprecht, Gabrielle; Roghani, Roham Salman; Vincoff, Sophia; Shin, Iljin; Zhao, Yiquan; Kim, So Young; McCall, Shannon; Hong, Jiyong; Hsu, David S

384 Motives for kratom self-medication: contents of public comments solicited by the FDA

384. 克拉托姆自我用药的动机:FDA征集的公众意见内容

Williams, Carly S; Li, Xin; Jang, Hongjun; Anand, Jay Ramanlal; Lim, Won Young; Lee, Hyejin; Parks, Julie; Zhang, Xingyuan; Xie, Jialiu; Zhao, Jinshi; Wu, Di; Armstrong, Andrew J; Bowser, Jessica L; Zou, Lee; Hong, Jiyong; Somarelli, Jason A; Vaziri, Cyrus; Zhou, Pei; Tobacyk, Julia; Parks, Brian; Brents, Lisa