Dual activation of GCGR/GLP1R signaling ameliorates intestinal fibrosis via metabolic regulation of histone H3K9 lactylation in epithelial cells.
GCGR/GLP1R 信号的双重激活通过代谢调节上皮细胞中的组蛋白 H3K9 乳酸化来改善肠道纤维化
期刊:Acta Pharmaceutica Sinica B
影响因子:14.6
doi:10.1016/j.apsb.2024.11.017
Liu Han, Hong Yujie, Chen Hui, Wang Xianggui, Dong Jiale, Li Xiaoqian, Shi Zihan, Zhao Qian, Zhou Longyuan, Wang JiaXin, Zeng Qiuling, Tang Qinglin, Liu Qi, Rieder Florian, Chen Baili, Chen Minhu, Wang Rui, Zhang Yao, Mao Ren, Jiang Xianxing
