NF546 [4,4'-(carbonylbis(imino-3,1-phenylene-carbonylimino-3,1-(4-methyl-phenylene)-carbonylimino))-bis(1,3-xylene-alpha,alpha'-diphosphonic acid) tetrasodium salt] is a non-nucleotide P2Y11 agonist and stimulates release of interleukin-8 from human monocyte-derived dendritic cells
NF546 [4,4'-(羰基双(亚氨基-3,1-亚苯基-羰基亚氨基-3,1-(4-甲基-亚苯基)-羰基亚氨基))-双(1,3-二甲苯-α,α'-二膦酸)四钠盐] 是一种非核苷酸 P2Y11 激动剂，可刺激人类单核细胞衍生的树突状细胞释放白细胞介素-8
期刊:Journal of Pharmacology and Experimental Therapeutics
影响因子:3.1
doi:10.1124/jpet.109.157750
Sabine Meis, Alexandra Hamacher, Darunee Hongwiset, Claudia Marzian, Michael Wiese, Niels Eckstein, Hans-Dieter Royer, Didier Communi, Jean-Marie Boeynaems, Ralf Hausmann, Günther Schmalzing, Matthias U Kassack
