日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

The phosphatase activity of the PPP2R5D-PP2A holoenzyme modulates liprin-α1 liquid-liquid phase separation.

PPP2R5D-PP2A 全酶的磷酸酶活性调节脂蛋白-α1 液-液相分离

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1016/j.jbc.2025.110349
Mayer Abigail, Derua Rita, Spahn Elijah, Verbinnen Iris, Zhang Yang, Guzman Michelle, Swingle Mark R, Wadzinski Brian E, Honkanen Richard, Janssens Veerle, Xia Houhui
其它
发表日期：2025
文献求助 收藏

Synaptic Gα12/13 signaling establishes hippocampal PV inhibitory circuits

突触 Gα12/13 信号建立海马 PV 抑制回路

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:
doi:10.1073/pnas.2407828121
Krassimira Garbett #, Baris Tosun #, Jaybree M Lopez, Cassandra M Smith, Kelly Honkanen, Richard C Sando
信号转导
Hippo
发表日期：2024
文献求助 收藏

Quantum-based modeling implies that bidentate Arg(89)-substrate binding enhances serine/threonine protein phosphatase-2A(PPP2R5D/PPP2R1A/PPP2CA)-mediated dephosphorylation

基于量子力学的建模表明，双齿Arg(89)底物结合增强了丝氨酸/苏氨酸蛋白磷酸酶-2A(PPP2R5D/PPP2R1A/PPP2CA)介导的去磷酸化作用。

期刊:Frontiers in Cell and Developmental Biology
影响因子:4.3
doi:10.3389/fcell.2023.1141804
Salter, E Alan; Wierzbicki, Andrzej; Honkanen, Richard E; Swingle, Mark R
信号转导
PPP2R5D
磷酸化
发表日期：2023
文献求助 收藏

Editorial: Deciphering the etiology of rare genetic disorders associated with protein phosphatases

社论：解读与蛋白磷酸酶相关的罕见遗传疾病的病因

期刊:Frontiers in Cell and Developmental Biology
影响因子:4.3
doi:10.3389/fcell.2023.1241606
Janssens, Veerle; Wadzinski, Brian E; Li, Chenchen; Honkanen, Richard E
信号转导
发表日期：2023
文献求助 收藏

FAK Activation Promotes SMC Dedifferentiation via Increased DNA Methylation in Contractile Genes

FAK激活通过增加收缩基因的DNA甲基化促进SMC去分化

期刊:Circulation Research
影响因子:16.2
doi:10.1161/CIRCRESAHA.121.319066
Jeong, Kyuho; Murphy, James M; Kim, Jung-Hyun; Campbell, Pamela Moore; Park, Hyeonsoo; Rodriguez, Yelitza A R; Choi, Chung-Sik; Kim, Jun-Sub; Park, Sangwon; Kim, Hyun Joon; Scammell, Jonathan G; Weber, David S; Honkanen, Richard E; Schlaepfer, David D; Ahn, Eun-Young Erin; Lim, Ssang-Taek Steve
DNA甲基化
表观遗传
DNA甲基化
FAK
发表日期：2021
文献求助 收藏

Inhibitors of Serine/Threonine Protein Phosphatases: Biochemical and Structural Studies Provide Insight for Further Development

丝氨酸/苏氨酸蛋白磷酸酶抑制剂：生化和结构研究为进一步开发提供见解

期刊:Current Medicinal Chemistry
影响因子:3.5
doi:10.2174/0929867325666180508095242
Swingle, Mark R; Honkanen, Richard E
信号转导
发表日期：2019
文献求助 收藏

Targeting phosphatases in cancer: suppression of many versus the ablation of one

癌症治疗中靶向磷酸酶：抑制多种磷酸酶与仅消除一种磷酸酶。

期刊:Oncotarget
影响因子:
doi:10.18632/oncotarget.27201
D'Arcy, Brandon M; Prakash, Aishwarya; Honkanen, Richard E
肿瘤
肿瘤免疫
发表日期：2019
文献求助 收藏

PP1:Tautomycetin Complex Reveals a Path toward the Development of PP1-Specific Inhibitors

PP1：tautomycetin复合物揭示了开发PP1特异性抑制剂的途径

期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/jacs.7b09368
Choy, Meng S; Swingle, Mark; D'Arcy, Brandon; Abney, Kevin; Rusin, Scott F; Kettenbach, Arminja N; Page, Rebecca; Honkanen, Richard E; Peti, Wolfgang
发表日期：2017
文献求助 收藏

An Ultra-High-Throughput Screen for Catalytic Inhibitors of Serine/Threonine Protein Phosphatases Types 1 and 5 (PP1C and PP5C)

丝氨酸/苏氨酸蛋白磷酸酶1型和5型（PP1C和PP5C）催化抑制剂的超高通量筛选

期刊:SLAS Discovery
影响因子:2.7
doi:10.1177/1087057116668852
Swingle, Mark; Volmar, Claude-Henry; Saldanha, S Adrian; Chase, Peter; Eberhart, Christina; Salter, Edward A; D'Arcy, Brandon; Schroeder, Chad E; Golden, Jennifer E; Wierzbicki, Andrzej; Hodder, Peter; Honkanen, Richard E
信号转导
发表日期：2017
文献求助 收藏

Crystal structures and mutagenesis of PPP-family ser/thr protein phosphatases elucidate the selectivity of cantharidin and novel norcantharidin-based inhibitors of PP5C.

PPP家族丝氨酸/苏氨酸蛋白磷酸酶的晶体结构和诱变研究阐明了斑蝥素和新型去甲斑蝥素类PP5C抑制剂的选择性

期刊:Biochemical Pharmacology
影响因子:5.6
doi:10.1016/j.bcp.2016.03.011
Chattopadhyay Debasish, Swingle Mark R, Salter Edward A, Wood Eric, D'Arcy Brandon, Zivanov Catherine, Abney Kevin, Musiyenko Alla, Rusin Scott F, Kettenbach Arminja, Yet Larry, Schroeder Chad E, Golden Jennifer E, Dunham Wade H, Gingras Anne-Claude, Banerjee Surajit, Forbes David, Wierzbicki Andrzej, Honkanen Richard E
免疫/内分泌
发表日期：2016
文献求助 收藏