日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Safety, Tolerability, and Pharmacokinetics of NIM-1324 an Oral LANCL2 Agonist in a Randomized, Double-Blind, Placebo-Controlled Phase I Clinical Trial

随机、双盲、安慰剂对照的 I 期临床试验中口服 LANCL2 激动剂 NIM-1324 的安全性、耐受性和药代动力学

期刊:Cts-Clinical and Translational Science
影响因子:2.8
doi:10.1111/cts.70129
Leber, Andrew; Hontecillas, Raquel; Tubau-Juni, Nuria; Bassaganya-Riera, Josep
发表日期：2025
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Computational modeling of complex bioenergetic mechanisms that modulate CD4+ T cell effector and regulatory functions

对调节 CD4+ T 细胞效应和调节功能的复杂生物能量机制进行计算建模

期刊:npj Systems Biology and Applications
影响因子:3.5
doi:10.1038/s41540-022-00263-4
Baker, Ryan; Hontecillas, Raquel; Tubau-Juni, Nuria; Leber, Andrew J; Kale, Shiv; Bassaganya-Riera, Josep
细胞生物学
T细胞
CD4
发表日期：2022
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Exploratory studies with NX-13: oral toxicity and pharmacokinetics in rodents of an orally active, gut-restricted first-in-class therapeutic for IBD that targets NLRX1

NX-13的探索性研究：一种靶向NLRX1的、口服活性、肠道限制性、首创的IBD治疗药物在啮齿动物中的口服毒性和药代动力学研究

期刊:Drug and Chemical Toxicology
影响因子:1.9
doi:10.1080/01480545.2019.1679828
Leber, Andrew; Hontecillas, Raquel; Zoccoli-Rodriguez, Victoria; Ehrich, Marion; Chauhan, Jyoti; Bassaganya-Riera, Josep
毒理研究
发表日期：2022
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Variants at the MHC Region Associate With Susceptibility to Clostridioides difficile Infection: A Genome-Wide Association Study Using Comprehensive Electronic Health Records

MHC区域的变异与艰难梭菌感染的易感性相关：一项利用综合电子健康记录的全基因组关联研究

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2021.638913
Li, Jiang; Zhang, Yanfei; Jilg, Alexandria L; Wolk, Donna M; Khara, Harshit S; Kolinovsky, Amy; Rolston, David D K; Hontecillas, Raquel; Bassaganya-Riera, Josep; Williams, Marc S; Abedi, Vida; Lee, Ming Ta Michael
炎症/感染
发表日期：2021
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Nlrx1-Regulated Defense and Metabolic Responses to Aspergillus fumigatus Are Morphotype and Cell Type Specific

Nlrx1调控的对烟曲霉的防御和代谢反应具有形态型和细胞类型特异性。

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2021.749504
Kastelberg, Bridget; Ayubi, Tariq; Tubau-Juni, Nuria; Leber, Andrew; Hontecillas, Raquel; Bassaganya-Riera, Josep; Kale, Shiv D
信号转导
细胞生物学
代谢
发表日期：2021
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Abscisic acid enriched fig extract promotes insulin sensitivity by decreasing systemic inflammation and activating LANCL2 in skeletal muscle

富含脱落酸的无花果提取物通过减少全身炎症和激活骨骼肌中的LANCL2来促进胰岛素敏感性。

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-020-67300-2
Leber, Andrew; Hontecillas, Raquel; Tubau-Juni, Nuria; Zoccoli-Rodriguez, Victoria; Goodpaster, Bret; Bassaganya-Riera, Josep
炎症/感染
炎症
免疫/内分泌
发表日期：2020
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Identification of new regulatory genes through expression pattern analysis of a global RNA-seq dataset from a Helicobacter pylori co-culture system

通过对幽门螺杆菌共培养系统中的全局RNA-seq数据集进行表达模式分析，鉴定新的调控基因

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-020-68439-8
Tubau-Juni, Nuria; Bassaganya-Riera, Josep; Leber, Andrew; Zoccoli-Rodriguez, Victoria; Kronsteiner, Barbara; Viladomiu, Monica; Abedi, Vida; Philipson, Casandra W; Hontecillas, Raquel
信号转导
发表日期：2020
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High-resolution computational modeling of immune responses in the gut

肠道免疫反应的高分辨率计算模型

期刊:Gigascience
影响因子:3.9
doi:10.1093/gigascience/giz062
Verma, Meghna; Bassaganya-Riera, Josep; Leber, Andrew; Tubau-Juni, Nuria; Hoops, Stefan; Abedi, Vida; Chen, Xi; Hontecillas, Raquel
免疫/内分泌
发表日期：2019
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Activation of NLRX1 by NX-13 Alleviates Inflammatory Bowel Disease through Immunometabolic Mechanisms in CD4(+) T Cells

NX-13激活NLRX1通过CD4(+) T细胞的免疫代谢机制缓解炎症性肠病

期刊:Journal of Immunology
影响因子:3.4
doi:10.4049/jimmunol.1900364
Leber, Andrew; Hontecillas, Raquel; Zoccoli-Rodriguez, Victoria; Bienert, Catherine; Chauhan, Jyoti; Bassaganya-Riera, Josep
炎症
T细胞
炎症/感染
代谢
T细胞
细胞生物学
免疫代谢
CD4
免疫/内分泌
发表日期：2019
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NLRX1 Modulates Immunometabolic Mechanisms Controlling the Host-Gut Microbiota Interactions during Inflammatory Bowel Disease

NLRX1调节炎症性肠病期间控制宿主-肠道菌群相互作用的免疫代谢机制

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2018.00363
Leber, Andrew; Hontecillas, Raquel; Tubau-Juni, Nuria; Zoccoli-Rodriguez, Victoria; Abedi, Vida; Bassaganya-Riera, Josep
炎症
炎症/感染
代谢
微生物学
肠道菌群
免疫代谢
免疫/内分泌
发表日期：2018
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