日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The role of histone demethylase PHF2 as a tumour suppressor in hepatocellular carcinoma by regulating SRXN1

组蛋白去甲基化酶PHF2通过调控SRXN1在肝细胞癌中发挥抑癌作用

Thng, Dexter Kai Hao; Hooi, Lissa; Yong, Wai Khang; Kappei, Dennis; Toh, Tan Boon; Chow, Edward Kai-Hua

Functional combinatorial precision medicine for predicting and optimizing soft tissue sarcoma treatments.

功能性组合精准医学在预测和优化软组织肉瘤治疗中的应用

Chan Sharon Pei Yi, Rashid Masturah Bte Mohd Abdul, Lim Jhin Jieh, Goh Janice Jia Ni, Wong Wai Yee, Hooi Lissa, Ismail Nur Nadiah, Luo Baiwen, Chen Benjamin Jieming, Noor Nur Fazlin Bte Mohamed, Phua Brandon Xuan Ming, Villanueva Andre, Sam Xin Xiu, Ong Chin-Ann Johnny, Chia Claramae Shulyn, Abidin Suraya Zainul, Yong Ming-Hui, Kumar Krishan, Ooi London Lucien, Tay Timothy Kwang Yong, Woo Xing Yi, Toh Tan Boon, Yang Valerie Shiwen, Chow Edward Kai-Hua

Flash optimization of drug combinations for Acinetobacter baumannii with IDentif.AI-AMR.

利用 IDentif.AI-AMR 对鲍曼不动杆菌的药物组合进行快速优化

You Kui, Binte Mohamed Yazid Nurhidayah, Chong Li Ming, Hooi Lissa, Wang Peter, Zhuang Isaiah, Chua Stephen, Lim Ethan, Kok Alrick Zi Xin, Marimuthu Kalisvar, Vasoo Shawn, Ng Oon Tek, Chan Conrad E Z, Chow Edward Kai-Hua, Ho Dean

A functional personalised oncology approach against metastatic colorectal cancer in matched patient derived organoids.

针对转移性结直肠癌,采用功能性个性化肿瘤治疗方法,构建匹配的患者来源类器官

Thng Dexter Kai Hao, Hooi Lissa, Siew Bei En, Lee Kai-Yin, Tan Ian Jse-Wei, Lieske Bettina, Lin Norman Sihan, Kow Alfred Wei Chieh, Wang Shi, Rashid Masturah Bte Mohd Abdul, Ang Chermaine, Koh Jasmin Jia Min, Toh Tan Boon, Tan Ker-Kan, Chow Edward Kai-Hua

Splice-switch oligonucleotide-based combinatorial platform prioritizes synthetic lethal targets CHK1 and BRD4 against MYC-driven hepatocellular carcinoma

基于剪接开关寡核苷酸的组合平台优先靶向合成致死靶点 CHK1 和 BRD4,以对抗 MYC 驱动的肝细胞癌。

Thng, Dexter Kai Hao; Toh, Tan Boon; Pigini, Paolo; Hooi, Lissa; Dan, Yock Young; Chow, Pierce Kah-Hoe; Bonney, Glenn Kunnath; Rashid, Masturah Bte Mohd Abdul; Guccione, Ernesto; Wee, Dave Keng Boon; Chow, Edward Kai-Hua

Addressing antimicrobial resistance with the IDentif.AI platform: Rapidly optimizing clinically actionable combination therapy regimens against nontuberculous mycobacteria

利用 IDentif.AI 平台应对抗菌素耐药性:快速优化针对非结核分枝杆菌的临床可操作联合治疗方案

Mukherjee, Devika; Wang, Peter; Hooi, Lissa; Sandhu, Vedant; You, Kui; Blasiak, Agata; Chow, Edward Kai-Hua; Ho, Dean; Ee, Pui Lai Rachel

Targeted Inhibition of Purine Metabolism Is Effective in Suppressing Hepatocellular Carcinoma Progression.

靶向抑制嘌呤代谢可有效抑制肝细胞癌的进展

Chong Yong Chun, Toh Tan Boon, Chan Zhiling, Lin Quy Xiao Xuan, Thng Dexter Kai Hao, Hooi Lissa, Ding Zhaobing, Shuen Timothy, Toh Han Chong, Dan Yock Young, Bonney Glenn Kunnath, Zhou Lei, Chow Pierce, Wang Yulan, Benoukraf Touati, Chow Edward Kai-Hua, Han Weiping

Project IDentif.AI: Harnessing Artificial Intelligence to Rapidly Optimize Combination Therapy Development for Infectious Disease Intervention

IDentif.AI项目:利用人工智能快速优化传染病干预联合疗法的开发

Abdulla, Aynur; Wang, Boqian; Qian, Feng; Kee, Theodore; Blasiak, Agata; Ong, Yoong Hun; Hooi, Lissa; Parekh, Falgunee; Soriano, Rafael; Olinger, Gene G; Keppo, Jussi; Hardesty, Chris L; Chow, Edward K; Ho, Dean; Ding, Xianting