日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Epithelial sensing of vitamin A shapes intestinal antimicrobial defense

上皮细胞对维生素A的感知塑造肠道抗菌防御机制

Quinn, Gabriella; Propheter, Daniel C; Kulkarni, Kartik; Johnson, Matthew; Vale, Gonçalo; McDonald, Jeffrey G; Johnson, Ann; Hassell, Brian; Behrendt, Cassie L; Munshi, Nikhil V; Hooper, Lora V

A single-cell atlas of intestinal immune cells across the day-night cycle reveals dynamic populations.

昼夜循环中肠道免疫细胞的单细胞图谱揭示了动态的细胞群。

Maples Robert W, Quinn Gabriella, Srinivasan Tarun, Dende Chaitanya, Hooper Lora V, Pfeiffer Julie K

Intestinal REG3 Lectins Protect against Alcoholic Steatohepatitis by Reducing Mucosa-Associated Microbiota and Preventing Bacterial Translocation

肠道REG3凝集素通过减少黏膜相关微生物群和阻止细菌移位来预防酒精性脂肪性肝炎

Wang, Lirui; Fouts, Derrick E; Stärkel, Peter; Hartmann, Phillipp; Chen, Peng; Llorente, Cristina; DePew, Jessica; Moncera, Kelvin; Ho, Samuel B; Brenner, David A; Hooper, Lora V; Schnabl, Bernd

Joint fluid multi-omics improves diagnostic confidence during evaluation of children with presumed septic arthritis.

关节液多组学分析可提高对疑似化脓性关节炎患儿的诊断信心。

Peña-López Yolanda, Tareen Naureen G, Zhang Bo, Raman Indu, Arana Carlos A, Zhu Chengsong, Liu Yang, Selvakumar Pratibha, van Oers Nicolai S C, Morris Simrat, Hooper Lora V, Copley Lawson A B, Raj Prithvi

Microbiota-derived short-chain fatty acids mediate Candida albicans gastrointestinal colonization resistance

肠道菌群来源的短链脂肪酸介导白色念珠菌对胃肠道定植的抵抗力。

Mishra, Animesh A; Coughlin, Laura A; Poulides, Nicole; Kim, Jiwoong; Zhan, Xiaowei; Gan, Shuheng; Winter, Sebastian E; Zarek, Christina M; Hooper, Lora V; Koh, Andrew Y

Translational control of innate barrier defense by the gut microbiota

肠道菌群对先天屏障防御的翻译调控

Li, Yun; Wu, Runrun; Ma, Xianda; Zhang, Jianglin; Ma, Junjie; Duan, Yiran; Hassell, Brian; Ruhn, Kelly A; Behrendt, Cassie L; Dende, Chaitanya; Wang, Li; Lemoff, Andrew; Raj, Prithvi; Kuang, Zheng; Hooper, Lora V

Timing of immune checkpoint blockade shapes anti-tumor immunity via a clock-dependent chemokine axis

免疫检查点阻断的时机通过时钟依赖性趋化因子轴塑造抗肿瘤免疫。

Lichterman, Jake N; Srinivasan, Tarun; Wang, Ruheng; Dende, Chaitanya; Zarek, Christina; Ramirez, Josue I; Park, Noheon; Wang, Hesuiyuan; Li, Wenling; Kim, Jiwoong; Coughlin, Laura; Poulides, Nicole; Sabaeifard, Parastoo; Palmer, Suzette N; Morrill, Aidan C; Hassell, Brian; Shelton, John M; Li, Xin V; Evers, Bret M; Zhan, Xiaowei; Takahashi, Joseph S; Hooper, Lora V; Koh, Andrew Y

Resistin-like molecule γ attacks cardiomyocyte membranes and promotes ventricular tachycardia

抵抗素样分子γ攻击心肌细胞膜并促进室性心动过速

Kumowski, Nina; Pabel, Steffen; Grune, Jana; Momin, Noor; Ninh, Van K; Stengel, Laura; Mentkowski, Kyle I; Iwamoto, Yoshiko; Zheng, Yi; Lee, I-Hsiu; Matthias, Jessica; Wirth, Jan O; Pulous, Fadi E; Seung, Hana; Paccalet, Alexandre; Muse, Charlotte G; Ting, Kenneth K Y; Delgado, Paul; Lewis, Andrew J M; Kaushal, Vaishali; Kreso, Antonia; Brown, Dennis; Hayat, Sikander; Kramann, Rafael; Swirski, Filip K; Naxerova, Kamila; Propheter, Daniel C; Hooper, Lora V; Moskowitz, Michael A; King, Kevin R; Rosenthal, Nadia; Hulsmans, Maarten; Nahrendorf, Matthias

The gut microbiota directs vitamin A flux to regulate intestinal T cell development.

肠道菌群引导维生素 A 的流动,从而调节肠道 T 细胞的发育。

Srinivasan Tarun, Dende Chaitanya, Ruhn Kelly A, Moye Stefanie L, Johnson Ann, Behrendt Cassie L, Hassell Brian, Vale Gonçalo, Kim Jiwoong, Lichterman Jake N, Liang Chaoying, Arana Carlos, Raj Prithvi, Zhan Xiaowei, McDonald Jeffrey G, Koh Andrew Y, Hooper Lora V

Susceptible bacteria can survive antibiotic treatment in the mammalian gastrointestinal tract without evolving resistance.

易感细菌在哺乳动物胃肠道中能够耐受抗生素治疗而不产生耐药性

Rodrigues Marinelle, Sabaeifard Parastoo, Yildiz Muhammed Sadik, Lyon Adam, Coughlin Laura, Ahmed Sara, Poulides Nicole, Toprak Ahmet C, Behrendt Cassie, Wang Xiaoyu, Monogue Marguerite, Kim Jiwoong, Gan Shuheng, Zhan Xiaowei, Filkins Laura, Williams Noelle S, Hooper Lora V, Koh Andrew Y, Toprak Erdal