日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

NFAT5 governs cellular plasticity-driven resistance to KRAS-targeted therapy in pancreatic cancer

NFAT5 调控胰腺癌中细胞可塑性驱动的对 KRAS 靶向治疗的耐药性

Deng, Daiyong; Begum, Habeebunnisa; Liu, Tong; Zhang, Jiangyan; Zhang, Qiang; Chu, Ting-Yu; Li, Hong; Lemenze, Alexander; Hoque, Mainul; Soteropoulos, Patricia; Hou, Pingping

Systematic Characterization of p53-Regulated Long Noncoding RNAs across Human Cancers Reveals Remarkable Heterogeneity among Different Tumor Types.

对人类癌症中 p53 调控的长链非编码 RNA 进行系统表征,揭示了不同肿瘤类型之间显著的异质性

Regunath Kausik, Fomin Vitalay, Liu Zhaoqi, Wang Pingzhang, Hoque Mainul, Tian Bin, Rabadan Raul, Prives Carol

Rapidly Correcting Frameshift Mutations in the Mycobacterium tuberculosis orn Gene Produce Reversible Ethambutol Resistance and Small-Colony-Variant Morphology

快速纠正结核分枝杆菌orn基因中的移码突变可产生可逆的乙胺丁醇耐药性和小菌落变异形态

Safi, Hassan; Lingaraju, Subramanya; Ma, Shuyi; Husain, Seema; Hoque, Mainul; Soteropoulos, Patricia; Rustad, Tige; Sherman, David R; Alland, David

The C9ORF72 Gene, Implicated in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia, Encodes a Protein That Functions in Control of Endothelin and Glutamate Signaling.

C9ORF72 基因与肌萎缩侧索硬化症和额颞叶痴呆症有关,它编码的蛋白质在控制内皮素和谷氨酸信号传导中发挥作用

Fomin Vitalay, Richard Patricia, Hoque Mainul, Li Cynthia, Gu Zhuoying, Fissore-O'Leary Mercedes, Tian Bin, Prives Carol, Manley James L

Intronic cleavage and polyadenylation regulates gene expression during DNA damage response through U1 snRNA

内含子切割和多聚腺苷酸化通过U1 snRNA调控DNA损伤反应过程中的基因表达。

Devany, Emral; Park, Ji Yeon; Murphy, Michael R; Zakusilo, George; Baquero, Jorge; Zhang, Xiaokan; Hoque, Mainul; Tian, Bin; Kleiman, Frida E

The Nrd1-like protein Seb1 coordinates cotranscriptional 3' end processing and polyadenylation site selection

Nrd1样蛋白Seb1协调共转录3'末端加工和多聚腺苷酸化位点选择。

Lemay, Jean-François; Marguerat, Samuel; Larochelle, Marc; Liu, Xiaochuan; van Nues, Rob; Hunyadkürti, Judit; Hoque, Mainul; Tian, Bin; Granneman, Sander; Bähler, Jürg; Bachand, François

Alternative cleavage and polyadenylation in spermatogenesis connects chromatin regulation with post-transcriptional control

精子发生过程中的选择性切割和多聚腺苷酸化将染色质调控与转录后调控联系起来。

Li, Wencheng; Park, Ji Yeon; Zheng, Dinghai; Hoque, Mainul; Yehia, Ghassan; Tian, Bin

RNAP II CTD tyrosine 1 performs diverse functions in vertebrate cells

RNA聚合酶II CTD酪氨酸1在脊椎动物细胞中发挥多种功能。

Hsin, Jing-Ping; Li, Wencheng; Hoque, Mainul; Tian, Bin; Manley, James L

The conserved intronic cleavage and polyadenylation site of CstF-77 gene imparts control of 3' end processing activity through feedback autoregulation and by U1 snRNP

CstF-77基因保守的内含子切割和多聚腺苷酸化位点通过反馈自调节和U1 snRNP调控3'末端加工活性。

Luo, Wenting; Ji, Zhe; Pan, Zhenhua; You, Bei; Hoque, Mainul; Li, Wencheng; Gunderson, Samuel I; Tian, Bin

Drug-induced reactivation of apoptosis abrogates HIV-1 infection

药物诱导的细胞凋亡再激活可消除 HIV-1 感染

Hanauske-Abel, Hartmut M; Saxena, Deepti; Palumbo, Paul E; Hanauske, Axel-Rainer; Luchessi, Augusto D; Cambiaghi, Tavane D; Hoque, Mainul; Spino, Michael; D'Alliessi Gandolfi, Darlene; Heller, Debra S; Singh, Sukhwinder; Park, Myung Hee; Cracchiolo, Bernadette M; Tricta, Fernando; Connelly, John; Popowicz, Anthony M; Cone, Richard A; Holland, Bart; Pe'ery, Tsafi; Mathews, Michael B