日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

PSKH1 kinase activity is differentially modulated via allosteric binding of Ca(2+) sensor proteins

PSKH1激酶活性受Ca(2+)传感器蛋白变构结合的差异性调节。

Horne, Christopher R; Dite, Toby A; Young, Samuel N; Mather, Lucy J; Dagley, Laura F; Johnson, Jared L; Yaron-Barir, Tomer M; Huntsman, Emily M; Daly, Leonard A; Byrne, Dominic P; Cadell, Antonia L; Ng, Boaz H; Yousef, Jumana; Multari, Dylan H; Shen, Lianju; McAloon, Luke M; Manning, Gerard; Febbraio, Mark A; Means, Anthony R; Cantley, Lewis C; Tanzer, Maria C; Croucher, David R; Eyers, Claire E; Eyers, Patrick A; Scott, John W; Murphy, James M

Unconventional binding of calmodulin to CHK2 kinase inhibits catalytic activity.

钙调蛋白与 CHK2 激酶的非常规结合抑制了其催化活性。

Horne Christopher R, Wang Tingting, Young Samuel N, Dite Toby A, Nyvall Hunter G, Suresh Sushant, Davies Katherine A, Gonzalez Castro Abner, Vaibhav Vineet, Mather Lucy J, Dagley Laura F, Belousoff Matthew J, Manning Gerard, Means Anthony R, Burke John E, Petersen Janni, Scott John W, Murphy James M

Mechanism of NanR transcriptional activation of sialic acid metabolism in Streptococcus pneumoniae

肺炎链球菌中NanR转录激活唾液酸代谢的机制

Wood, David M; Johns, Ashleigh S; Tillett, Zachary D; Shearer, Heather L; Panjikar, Santosh; Mok, Yee-Foong; Griffin, Michael D W; Allison, Timothy M; North, Rachel A; Pace, Paul E; Demeler, Borries; Hampton, Mark B; Dobson, Renwick C J; Horne, Christopher R

Unusual PDGFRB fusion reveals novel mechanism of kinase activation in Ph-like B-ALL

罕见的PDGFRB融合揭示了Ph样B细胞急性淋巴细胞白血病中激酶激活的新机制

Sadras, Teresa; Jalud, Fatimah B; Kosasih, Hansen J; Horne, Christopher R; Brown, Lauren M; El-Kamand, Sam; de Bock, Charles E; McAloney, Lachlan; Ng, Ashley P; Davidson, Nadia M; Ludlow, Louise E A; Oshlack, Alicia; Cowley, Mark J; Khaw, Seong L; Murphy, James M; Ekert, Paul G

CaMKK2 as an emerging treatment target for bipolar disorder

CaMKK2作为双相情感障碍的新兴治疗靶点

Kaiser, Jacqueline; Nay, Kevin; Horne, Christopher R; McAloon, Luke M; Fuller, Oliver K; Muller, Abbey G; Whyte, Douglas G; Means, Anthony R; Walder, Ken; Berk, Michael; Hannan, Anthony J; Murphy, James M; Febbraio, Mark A; Gundlach, Andrew L; Scott, John W

Granulovirus PK-1 kinase activity relies on a side-to-side dimerization mode centered on the regulatory αC helix

颗粒病毒PK-1激酶活性依赖于以调控αC螺旋为中心的侧向二聚化模式。

Oliver, Michael R; Horne, Christopher R; Shrestha, Safal; Keown, Jeremy R; Liang, Lung-Yu; Young, Samuel N; Sandow, Jarrod J; Webb, Andrew I; Goldstone, David C; Lucet, Isabelle S; Kannan, Natarajan; Metcalf, Peter; Murphy, James M

SMCHD1's ubiquitin-like domain is required for N-terminal dimerization and chromatin localization

SMCHD1的泛素样结构域是N端二聚化和染色质定位所必需的。

Gurzau, Alexandra D; Horne, Christopher R; Mok, Yee-Foong; Iminitoff, Megan; Willson, Tracy A; Young, Samuel N; Blewitt, Marnie E; Murphy, James M

Using cryo-EM to uncover mechanisms of bacterial transcriptional regulation

利用冷冻电镜揭示细菌转录调控机制

Wood, David M; Dobson, Renwick C J; Horne, Christopher R

The basis for non-canonical ROK family function in the N-acetylmannosamine kinase from the pathogen Staphylococcus aureus.

金黄色葡萄球菌病原体 N-乙酰甘露糖胺激酶中非典型 ROK 家族功能的基础

Coombes David, Davies James S, Newton-Vesty Michael C, Horne Christopher R, Setty Thanuja G, Subramanian Ramaswamy, Moir James W B, Friemann Rosmarie, Panjikar Santosh, Griffin Michael D W, North Rachel A, Dobson Renwick C J

"Just a spoonful of sugar...": import of sialic acid across bacterial cell membranes

“只需一勺糖……”:唾液酸跨越细菌细胞膜的输入

North, Rachel A; Horne, Christopher R; Davies, James S; Remus, Daniela M; Muscroft-Taylor, Andrew C; Goyal, Parveen; Wahlgren, Weixiao Yuan; Ramaswamy, S; Friemann, Rosmarie; Dobson, Renwick C J