日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Encapsulation and Delivery of the Kinase Inhibitor PIK-75 by Organic Core High-Density Lipoprotein-Like Nanoparticles Targeting Scavenger Receptor Class B Type 1.

利用有机核心高密度脂蛋白样纳米颗粒封装和递送激酶抑制剂PIK-75靶向清道夫受体B类1型

Rink Jonathan S, Lin Adam Y, Calvert Andrea E, Kwon David, Moxley Alexandra, Henrich Stephen E, Mohammadlou Aliakbar, Zhang Xu Hannah, Wu Xiwei, Querfeld Christiane, Griend Donald J Vander, Yin Hongwei Holly, Horne David A, Nguyen SonBinh T, Rosen Steven T, Gordon Leo I, Thaxton Colby Shad

Association of pharmacokinetic biomarkers with early immune recovery following HLA-haploidentical hematopoietic cell transplantation

药代动力学生物标志物与HLA半相合造血干细胞移植后早期免疫恢复的相关性

Shen, Guofang; Synold, Timothy W; Khan, Shanzay; Horne, David A; Kanakry, Christopher G; Nakamura, Ryotaro

Association of Structural Maintenance of Chromosome-1A Phosphorylation with Progression of Breast Cancer

染色体1A磷酸化结构维持与乳腺癌进展的关联

Yadav, Sushma; Kowolik, Claudia M; Schmolze, Daniel; Yuan, Yuan; Lin, Min; Riggs, Arthur D; Horne, David A

Design and Synthesis of New Substituted Pyrazolopyridines with Potent Antiproliferative Activity

设计并合成具有强效抗增殖活性的新型取代吡唑并吡啶类化合物

Giannouli, Vassiliki; Lougiakis, Nikolaos; Kostakis, Ioannis K; Pouli, Nicole; Marakos, Panagiotis; Skaltsounis, Alexios-Leandros; Horne, David A; Nam, Sangkil; Gioti, Katerina; Tenta, Roxane

Template-Catalyzed, Disulfide Conjugation of Monoclonal Antibodies Using a Natural Amino Acid Tag

利用天然氨基酸标签进行模板催化的单克隆抗体二硫键偶联

King, Jeremy D; Ma, Yuelong; Kuo, Yi-Chiu; Bzymek, Krzysztof P; Goodstein, Leah H; Meyer, Kassondra; Moore, Roger E; Crow, Desiree; Colcher, David M; Singh, Gagandeep; Horne, David A; Williams, John C

Synthesis facilitates an understanding of the structural basis for translation inhibition by the lissoclimides

合成有助于理解利索克利米德类化合物抑制翻译的结构基础。

Könst, Zef A; Szklarski, Anne R; Pellegrino, Simone; Michalak, Sharon E; Meyer, Mélanie; Zanette, Camila; Cencic, Regina; Nam, Sangkil; Voora, Vamsee K; Horne, David A; Pelletier, Jerry; Mobley, David L; Yusupova, Gulnara; Yusupov, Marat; Vanderwal, Christopher D

Natural-Based Indirubins Display Potent Cytotoxicity toward Wild-Type and T315I-Resistant Leukemia Cell Lines

天然靛玉红对野生型和T315I耐药性白血病细胞系均表现出强效细胞毒性

Gaboriaud-Kolar, Nicolas; Myrianthopoulos, Vasillios; Vougogiannopoulou, Konstantina; Gerolymatos, Panagiotis; Horne, David A; Jove, Richard; Mikros, Emmanuel; Nam, Sangkil; Skaltsounis, Alexios-Leandros

A novel synthetic derivative of the natural product berbamine inhibits cell viability and induces apoptosis of human osteosarcoma cells, associated with activation of JNK/AP-1 signaling

一种新型的天然产物小檗碱合成衍生物能够抑制细胞活力并诱导人骨肉瘤细胞凋亡,这与JNK/AP-1信号通路的激活有关。

Yang, Fan; Nam, Sangkil; Zhao, Robin; Tian, Yan; Liu, Lucy; Horne, David A; Jove, Richard