Horne W Seth相关文献与解析，生知库 | 链接生命科学的每一步

A Predictive Model for Thiol Reactivity of N-Heteroaryl Î±-Methylene-Î³-LactamsâA Medicinally Relevant Covalent Reactive Group.

N-杂芳基α-亚甲基-α-内酰胺硫醇反应性的预测模型——一种具有药用价值的共价反应基团

期刊:Journal of Medicinal Chemistry

影响因子:6.8

doi:10.1021/acs.jmedchem.5c00833

Meehan Mariah C, Scofield Grace E, Stahl Corrinne E, Wolfe Jacob A, Horne W Seth, Liu Peng, Brummond Kay M

其它

发表日期：2025

文献求助收藏

Impact of Strand Edge N-Amination on the Stability of a Parallel β-Hairpin Fold

链边缘N-氨基化对平行β-发夹折叠稳定性的影响

期刊:Journal of Organic Chemistry

影响因子:3.6

doi:10.1021/acs.joc.5c02479

Starnes, Syrah K; Horne, W Seth; Del Valle, Juan R

发表日期：2025

文献求助收藏

Structural and Functional Mimicry of the Antimicrobial Defensin Plectasin by Analogues with Engineered Backbone Composition

通过工程化骨架组成类似物模拟抗菌防御素 Plectasin 的结构和功能

期刊:Chembiochem

影响因子:2.8

doi:10.1002/cbic.202400951

Harmon, Thomas W; Song, Junming; Gulewicz, Andrew J; Di, Y Peter; Horne, W Seth

发表日期：2025

文献求助收藏

Effects of altered backbone composition on the folding kinetics and mechanism of an ultrafast-folding protein

改变骨架组成对超快折叠蛋白折叠动力学和机制的影响

期刊:Chemical Science

影响因子:7.4

doi:10.1039/d3sc03976e

Santhouse, Jacqueline R; Leung, Jeremy M G; Chong, Lillian T; Horne, W Seth

发表日期：2024

文献求助收藏

Application of artificial backbone connectivity in the development of metalloenzyme mimics

人工骨架连接在金属酶模拟物开发中的应用

期刊:Current Opinion in Chemical Biology

影响因子:6.1

doi:10.1016/j.cbpa.2024.102509

Wolfe, Jacob A; Horne, W Seth

发表日期：2024

文献求助收藏

Probing effects of site-specific aspartic acid isomerization on structure and stability of GB1 through chemical protein synthesis

通过化学蛋白质合成法探究位点特异性天冬氨酸异构化对GB1结构和稳定性的影响

期刊:Protein Science

影响因子:5.2

doi:10.1002/pro.4883

Heath, Shelby L; Guseman, Alex J; Gronenborn, Angela M; Horne, W Seth

发表日期：2024

文献求助收藏

Backbone Modification in a Protein Hydrophobic Core

蛋白质疏水核心的骨架修饰

期刊:Chemistry-A European Journal

影响因子:3.7

doi:10.1002/chem.202401890

Lin, Yuhan; Horne, W Seth

发表日期：2024

文献求助收藏

Protein Backbone Alteration in Non-Hairpin β-Turns: Impacts on Tertiary Folded Structure and Folded Stability

非发夹β转角中蛋白质主链的改变：对三级折叠结构和折叠稳定性的影响

期刊:Chembiochem

影响因子:2.8

doi:10.1002/cbic.202300113

Harmon, Thomas W; Horne, W Seth

发表日期：2023

文献求助收藏

Backbone engineering in the hydrophobic core of villin headpiece

维林头件疏水核心的骨干工程

Manipulating the Unfolded State of a Folded Protein through Site-Specific Backbone Modification

通过位点特异性主链修饰来调控折叠蛋白的展开状态

A Predictive Model for Thiol Reactivity of N-Heteroaryl Î±-Methylene-Î³-LactamsâA Medicinally Relevant Covalent Reactive Group.

N-杂芳基α-亚甲基-α-内酰胺硫醇反应性的预测模型——一种具有药用价值的共价反应基团

Impact of Strand Edge N-Amination on the Stability of a Parallel β-Hairpin Fold

链边缘N-氨基化对平行β-发夹折叠稳定性的影响

Structural and Functional Mimicry of the Antimicrobial Defensin Plectasin by Analogues with Engineered Backbone Composition

通过工程化骨架组成类似物模拟抗菌防御素 Plectasin 的结构和功能

Effects of altered backbone composition on the folding kinetics and mechanism of an ultrafast-folding protein

改变骨架组成对超快折叠蛋白折叠动力学和机制的影响

Application of artificial backbone connectivity in the development of metalloenzyme mimics

人工骨架连接在金属酶模拟物开发中的应用

Probing effects of site-specific aspartic acid isomerization on structure and stability of GB1 through chemical protein synthesis

通过化学蛋白质合成法探究位点特异性天冬氨酸异构化对GB1结构和稳定性的影响

Backbone Modification in a Protein Hydrophobic Core

蛋白质疏水核心的骨架修饰

Protein Backbone Alteration in Non-Hairpin β-Turns: Impacts on Tertiary Folded Structure and Folded Stability

非发夹β转角中蛋白质主链的改变：对三级折叠结构和折叠稳定性的影响

Backbone engineering in the hydrophobic core of villin headpiece

维林头件疏水核心的骨干工程

Manipulating the Unfolded State of a Folded Protein through Site-Specific Backbone Modification

通过位点特异性主链修饰来调控折叠蛋白的展开状态

A Predictive Model for Thiol Reactivity of N-Heteroaryl Î±-Methylene-Î³-LactamsâA Medicinally Relevant Covalent Reactive Group.

N-杂芳基α-亚甲基-α-内酰胺硫醇反应性的预测模型——一种具有药用价值的共价反应基团

Impact of Strand Edge N-Amination on the Stability of a Parallel β-Hairpin Fold

链边缘N-氨基化对平行β-发夹折叠稳定性的影响

Structural and Functional Mimicry of the Antimicrobial Defensin Plectasin by Analogues with Engineered Backbone Composition

通过工程化骨架组成类似物模拟抗菌防御素 Plectasin 的结构和功能

Effects of altered backbone composition on the folding kinetics and mechanism of an ultrafast-folding protein

改变骨架组成对超快折叠蛋白折叠动力学和机制的影响

Application of artificial backbone connectivity in the development of metalloenzyme mimics

人工骨架连接在金属酶模拟物开发中的应用

Probing effects of site-specific aspartic acid isomerization on structure and stability of GB1 through chemical protein synthesis

通过化学蛋白质合成法探究位点特异性天冬氨酸异构化对GB1结构和稳定性的影响

Backbone Modification in a Protein Hydrophobic Core

蛋白质疏水核心的骨架修饰

Protein Backbone Alteration in Non-Hairpin β-Turns: Impacts on Tertiary Folded Structure and Folded Stability

非发夹β转角中蛋白质主链的改变：对三级折叠结构和折叠稳定性的影响

A Predictive Model for Thiol Reactivity of N-Heteroaryl Î±-Methylene-Î³-LactamsâA Medicinally Relevant Covalent Reactive Group.