IGH::FENDRR and specific KRAS mutations define a novel B-ALL molecular subtype with poor chemotherapy response
IGH::FENDRR 和特定的 KRAS 突变定义了一种新型的 B 细胞急性淋巴细胞白血病 (B-ALL) 分子亚型,该亚型对化疗反应较差。
期刊:Blood
影响因子:23.1
doi:10.1182/blood.2025031102
Bendig, Sonja; Hartmann, Alina M; Wessels, Wiebke; Beder, Thomas; Kim, Rathana; Passet, Marie; Gao, Qingsong; Wolgast, Nadine; Horns, Johanna M; Alves Santos, Leonardo; Iben, Katharina; Steffen, Fabio D; Cantoni, Loredana; Kehden, Britta; Chitadze, Guranda; Künstner, Axel; Busch, Hauke; Bornhauser, Beat; Bourquin, Jean-Pierre; Leguay, Thibaut Tl; Boissel, Nicolas; Gökbuget, Nicola; Iacobucci, Ilaria; Mullighan, Charles G; Clappier, Emmanuelle; Baldus, Claudia D; Brüggemann, Monika; Bastian, Lorenz