日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Synthesis and biological characterization of an orally bioavailable lactate dehydrogenase-A inhibitor against pancreatic cancer

合成及生物学表征一种口服生物利用度高的乳酸脱氢酶A抑制剂对抗胰腺癌

Horrick Sharma ,Somrita Mondal ,Uzziah Urquiza ,Colter Esparza ,Seth Bartlett ,Landon Santa-Pinter ,Hanna Hill ,Madalyn White ,Pragya Sharma ,Lerin Luckett-Chastain ,Anne Cooper ,Mohammad Rasel ,Philip Gao ,Kevin P Battaile ,Surendra K Shukla ,Scott Lovell ,Michael A Ihnat

Exploration of a Large Virtual Chemical Space: Identification of Potent Inhibitors of Lactate Dehydrogenase-A against Pancreatic Cancer

探索大型虚拟化学空间:鉴定抗胰腺癌的强效乳酸脱氢酶A抑制剂

Horrick Sharma ,Pragya Sharma ,Uzziah Urquiza ,Lerin R Chastain ,Michael A Ihnat

New NSAID Conjugates as Potent and Selective COX-2 Inhibitors: Synthesis, Molecular Modeling and Biological Investigation

新型非甾体抗炎药缀合物作为强效选择性COX-2抑制剂:合成、分子建模和生物学研究

Bokhtia, Riham M; Panda, Siva S; Girgis, Adel S; Samir, Nermin; Said, Mona F; Abdelnaser, Anwar; Nasr, Soad; Bekheit, Mohamed S; Dawood, Abdelhameed S; Sharma, Horrick; Wade, Margaret; Sharma, Swapnil K; Ghanim, Amany M

Bivalent dopamine agonists with co-operative binding and functional activities at dopamine D2 receptors, modulate aggregation and toxicity of alpha synuclein protein

具有协同结合能力和多巴胺D2受体功能活性的二价多巴胺激动剂,可调节α-突触核蛋白的聚集和毒性。

Dinda, Bidyut; Das, Banibrata; Biswas, Swati; Sharma, Horrick; Armstrong, Christopher; Yedlapudi, Deepthi; Antonio, Tamara; Reith, Maarten; Dutta, Aloke K

Discovery of a small-molecule inhibitor of the TRIP8b-HCN interaction with efficacy in neurons

发现一种对神经元有效的TRIP8b-HCN相互作用的小分子抑制剂

Ye Han ,Iredia D Iyamu ,Matthew R Clutter ,Rama K Mishra ,Kyle A Lyman ,Chengwen Zhou ,Ioannis Michailidis ,Maya Y Xia ,Horrick Sharma ,Chi-Hao Luan ,Gary E Schiltz ,Dane M Chetkovich

Functionalized Graphene Oxide for Chemotherapeutic Drug Delivery and Cancer Treatment: A Promising Material in Nanomedicine

功能化氧化石墨烯用于化疗药物递送和癌症治疗:纳米医学领域一种极具前景的材料

Sharma, Horrick; Mondal, Somrita

Triple reuptake inhibitors as potential next-generation antidepressants: a new hope?

三重再摄取抑制剂作为潜在的下一代抗抑郁药:新的希望?

Sharma, Horrick; Santra, Soumava; Dutta, Aloke

Identification of a new class of MDM2 inhibitor that inhibits growth of orthotopic pancreatic tumors in mice

鉴定出一类可抑制小鼠原位胰腺肿瘤生长的新型 MDM2 抑制剂

Wei Wang, Jiang-Jiang Qin, Sukesh Voruganti, Ming-Hai Wang, Horrick Sharma, Shivaputra Patil, Jianwei Zhou, Hui Wang, Debabrata Mukhopadhyay, John K Buolamwini, Ruiwen Zhang

The pyrido[b]indole MDM2 inhibitor SP-141 exerts potent therapeutic effects in breast cancer models

吡啶并[b]吲哚 MDM2 抑制剂 SP-141 在乳腺癌模型中发挥强效治疗作用

Wei Wang, Jiang-Jiang Qin, Sukesh Voruganti, Kalkunte S Srivenugopal, Subhasree Nag, Shivaputra Patil, Horrick Sharma, Ming-Hai Wang, Hui Wang, John K Buolamwini, Ruiwen Zhang

Pharmacological and behavioral characterization of D-473, an orally active triple reuptake inhibitor targeting dopamine, serotonin and norepinephrine transporters

D-473 是一种口服三重再摄取抑制剂,靶向多巴胺、血清素和去甲肾上腺素转运体,其药理学和行为学特征

Aloke K Dutta, Soumava Santra, Horrick Sharma, Chandrashekhar Voshavar, Liping Xu, Omar Mabrouk, Tamara Antonio, Maarten E A Reith