日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Multiomic Immune Profiling of Pediatric Transplant Recipients Identifies Cell States Associated with Vaccine Response

对儿童移植受者进行多组学免疫分析,可识别与疫苗反应相关的细胞状态

Wedel, Johannes; Tang, Ying; Alsairafi, Bayan; Do, Vicki; Maslyar, Madeline; Fleming, Ryan; Schwartz, Marc A; Gerdemann, Ulrike; Albanese, Alexandre; Mitsialis, Vanessa; Collen, Lauren V; Nishitani, Miki; Bresnahan, Mairead; Saccocia, Gwen; Bearup, Richelle; Okoroafor, Ibeawuchi; Siegel, Steven J; Wachter, Franziska; Waters, Katherine; Weichert-Leahey, Nina; Clarke, Nigel J; Mandl, Kenneth D; Kean, Leslie S; Snapper, Scott B; Briscoe, David M; Horwitz, Bruce H

Variants and vaccines impact nasal immunity over three waves of SARS-CoV-2

SARS-CoV-2 变异株和疫苗在三波疫情中均对鼻腔免疫力产生影响

Walsh, Jaclyn M L; Miao, Vincent N; Owings, Anna H; Tang, Ying; Bromley, Joshua D; Kazer, Samuel W; Kimler, Kyle; Asare, Chelsea; Ziegler, Carly G K; Ibrahim, Samira; Jivanjee, Tasneem; George, Micayla; Navia, Andrew W; Drake, Riley S; Parker, Adam; Billingsley, Benjamin C; Dotherow, Paul; Tarugu, Spurthi; Kota, Sai K; Laird, Hannah; Wichman, T Grant; Davis, Yesenia T; Dhaliwal, Neha S; Pride, Yilianys; Guo, Yanglin; Senitko, Michal; Harvey, Jessie; Bates, John T; Diamond, Gill; Garrett, Michael R; Robinson, D Ashley; Frame, I J; Lyons, Jonathan J; Robinson, Tanya O; Shalek, Alex K; Horwitz, Bruce H; Glover, Sarah C; Ordovas-Montanes, Jose

Enhanced Production of Lipid Mediators in Plasma and Activation of DNA Damage Pathways in PBMCs Are Correlated With the Severity of Ancestral SARS-CoV-2 Infection

血浆中脂质介质生成增加和外周血单核细胞中DNA损伤通路激活与祖先SARS-CoV-2感染的严重程度相关

Tomalka, Jeffrey A; Owings, Anna; Galeas-Pena, Michelle; Ziegler, Carly G K; Robinson, Tanya O; Wichman, Thomas G; Laird, Hannah; Williams, Haley B; Ghaliwal, Neha S; Everman, Steven; Zafar, Yousaf; Walsh, Jaclyn M L; Shalek, Alex K; Horwitz, Bruce H; Ordovas-Montanes, Jose; Glover, Sarah C; Gibert, Yann

Humoral profiles of toddlers and young children following SARS-CoV-2 mRNA vaccination.

SARS-CoV-2 mRNA疫苗接种后幼儿和儿童的体液特征

Nziza Nadège, Deng Yixiang, Wood Lianna, Dhanoa Navneet, Dulit-Greenberg Naomi, Chen Tina, Kane Abigail S, Swank Zoe, Davis Jameson P, Demokritou Melina, Chitnis Anagha P, Fasano Alessio, Edlow Andrea G, Jain Nitya, Horwitz Bruce H, McNamara Ryan P, Walt David R, Lauffenburger Douglas A, Julg Boris, Shreffler Wayne G, Alter Galit, Yonker Lael M

COVID-19 mRNA Vaccines Induce Robust Levels of IgG but Limited Amounts of IgA Within the Oronasopharynx of Young Children

新冠病毒mRNA疫苗可在幼儿口咽部诱导产生高水平的IgG抗体,但IgA抗体含量有限。

Tang, Ying; Boribong, Brittany P; Swank, Zoe N; Demokritou, Melina; Luban, Maria A F; Fasano, Alessio; Du, Michelle; Wolf, Rebecca L; Griffiths, Joseph; Shultz, John; Borberg, Ella; Chalise, Sujata; Gonzalez, Wanda I; Walt, David R; Yonker, Lael M; Horwitz, Bruce H

An enhanced IL17 and muted type I interferon nasal epithelial cell state characterizes severe COVID-19 with fungal coinfection

重症 COVID-19 合并真菌感染的特征是鼻上皮细胞中 IL-17 水平升高和 I 型干扰素水平降低。

Ziegler, Carly G K; Owings, Anna H; Galeas-Pena, Michelle; Kazer, Samuel W; Miao, Vincent N; Navia, Andrew W; Tang, Ying; Bromley, Joshua D; Lotfy, Peter; Sloan, Meredith; Laird, Hannah; Williams, Haley B; George, Micayla; Drake, Riley S; Pride, Yilianys; Abraham, George E 3rd; Senitko, Michal; Robinson, Tanya O; Diamond, Gill; Lionakis, Michail S; Shalek, Alex K; Ordovas-Montanes, Jose; Horwitz, Bruce H; Glover, Sarah C

The IL-10 receptor inhibits cell extrinsic signals necessary for STAT1-dependent macrophage accumulation during colitis

IL-10受体抑制结肠炎期间STAT1依赖性巨噬细胞聚集所必需的细胞外信号。

Patik, Izabel; Redhu, Naresh S; Eran, Alal; Bao, Bin; Nandy, Anubhab; Tang, Ying; El Sayed, Shorouk; Shen, Zeli; Glickman, Jonathan; Fox, James G; Snapper, Scott B; Horwitz, Bruce H

Enhanced production of eicosanoids in plasma and activation of DNA damage pathways in PBMCs are correlated with the severity of ancestral COVID-19 infection

血浆中类花生酸生成增加和外周血单核细胞中DNA损伤通路激活与先天性COVID-19感染的严重程度相关。

Tomalka, Jeffrey A; Owings, Anna; Galeas-Pena, Michelle; Ziegler, Carly G K; Robinson, Tanya O; Wichman, Thomas G; Laird, Hannah; Williams, Haley B; Dhaliwal, Neha S; Everman, Steven; Zafar, Yousaf; Shalek, Alex K; Horwitz, Bruce H; Ordovas-Montanes, Jose; Glover, Sarah C; Gibert, Yann

Severe COVID-19 is associated with fungal colonization of the nasopharynx and potent induction of IL-17 responses in the nasal epithelium

重症 COVID-19 与鼻咽部真菌定植和鼻上皮细胞中 IL-17 反应的强烈诱导有关。

Ziegler, Carly G K; Owings, Anna H; Miao, Vincent N; Navia, Andrew W; Tang, Ying; Bromley, Joshua D; Lotfy, Peter; Sloan, Meredith; Laird, Hannah; Williams, Haley B; George, Micayla; Drake, Riley S; Pride, Yilianys; Abraham, George E 3rd; Senitko, Michal; Robinson, Tanya O; Lionakis, Michail S; Shalek, Alex K; Ordovas-Montanes, Jose; Horwitz, Bruce H; Glover, Sarah C

Utilizing a reductionist model to study host-microbe interactions in intestinal inflammation

利用还原论模型研究肠道炎症中的宿主-微生物相互作用

Tsou, Amy M; Goettel, Jeremy A; Bao, Bin; Biswas, Amlan; Kang, Yu Hui; Redhu, Naresh S; Peng, Kaiyue; Putzel, Gregory G; Saltzman, Jeffrey; Kelly, Ryan; Gringauz, Jordan; Barends, Jared; Hatazaki, Mai; Frei, Sandra M; Emani, Rohini; Huang, Ying; Shen, Zeli; Fox, James G; Glickman, Jonathan N; Horwitz, Bruce H; Snapper, Scott B