日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Induction of Cyp2e1 contributes to asparaginase-induced hepatocyte sensitization to lipotoxicity.

Cyp2e1 的诱导有助于天冬酰胺酶诱导的肝细胞对脂毒性的敏感性

Zhu Yin, Wang Yuyin, Hoshitsuki Keito, Yang Da, Kokai Lauren, Ma Xiaochao, Xie Wen, Fernandez Christian A

Clinical Actionability of the NUDT15 *4 (p.R139H) Allele and Its Association With Hispanic Ethnicity

NUDT15 *4 (p.R139H) 等位基因的临床可操作性及其与西班牙裔种族的关联

Maillard, Maud; Nguyen, Jenny Q; Yang, Wenjian; Hoshitsuki, Keito; Relling, Mary V; Caudle, Kelly E; Crews, Kristine R; Jeha, Sima; Inaba, Hiroto; Pui, Ching-Hon; Bhatia, Smita; Karol, Seth E; Antillon-Klussmann, Federico G; Haidar, Cyrine E; Bhojwani, Deepa; Yang, Jun J

Duvelisib is a novel NFAT inhibitor that mitigates adalimumab-induced immunogenicity

Duvelisib 是一种新型 NFAT 抑制剂,可减轻阿达木单抗诱导的免疫原性

Aboli Bhingarkar #, Yuyin Wang #, Keito Hoshitsuki, Katherine Marie Eichinger, Sanjay Rathod, Yin Zhu, He Lyu, Andrew T McNutt, Larry W Moreland, Lee McDermott, David R Koes, Christian A Fernandez

Additive effects of TPMT and NUDT15 on thiopurine toxicity in children with acute lymphoblastic leukemia across multiethnic populations

TPMT 和 NUDT15 对多民族儿童急性淋巴细胞白血病硫嘌呤毒性的叠加效应

Maillard, Maud; Nishii, Rina; Yang, Wenjian; Hoshitsuki, Keito; Chepyala, Divyabharathi; Lee, Shawn H R; Nguyen, Jenny Q; Relling, Mary V; Crews, Kristine R; Leggas, Mark; Singh, Meenu; Suang, Joshua L Y; Yeoh, Allen E J; Jeha, Sima; Inaba, Hiroto; Pui, Ching-Hon; Karol, Seth E; Trehan, Amita; Bhatia, Prateek; Antillon Klussmann, Federico G; Bhojwani, Deepa; Haidar, Cyrine E; Yang, Jun J

Asparaginase-specific basophil recognition and activation predict Asparaginase hypersensitivity in mice

天冬酰胺酶特异性嗜碱性粒细胞识别和激活可预测小鼠对天冬酰胺酶的超敏反应

Sanjay Rathod ,Keito Hoshitsuki ,Yin Zhu ,Manda Ramsey ,Christian A Fernandez

Association of Inherited Genetic Factors With Drug-Induced Hepatic Damage Among Children With Acute Lymphoblastic Leukemia

遗传因素与急性淋巴细胞白血病患儿药物性肝损伤的关联

Yang, Wenjian; Karol, Seth E; Hoshitsuki, Keito; Lee, Shawn; Larsen, Eric C; Winick, Naomi; Carroll, William L; Loh, Mignon L; Raetz, Elizabeth A; Hunger, Stephen P; Winter, Stuart S; Dunsmore, Kimberly P; Devidas, Meenakshi; Relling, Mary V; Yang, Jun J

Clinical Pharmacogenetics Implementation Consortium Guideline for the Use of Aminoglycosides Based on MT-RNR1 Genotype

基于MT-RNR1基因型的氨基糖苷类药物临床药物遗传学实施联盟指南

McDermott, John Henry; Wolf, Joshua; Hoshitsuki, Keito; Huddart, Rachel; Caudle, Kelly E; Whirl-Carrillo, Michelle; Steyger, Peter S; Smith, Richard J H; Cody, Neal; Rodriguez-Antona, Cristina; Klein, Teri E; Newman, William G

Long-read HiFi sequencing of NUDT15: Phased full-gene haplotyping and pharmacogenomic allele discovery

NUDT15长读长HiFi测序:全基因单倍型分型和药物基因组学等位基因发现

Scott, Erick R; Yang, Yao; Botton, Mariana R; Seki, Yoshinori; Hoshitsuki, Keito; Harting, John; Baybayan, Primo; Cody, Neal; Nicoletti, Paola; Moriyama, Takaya; Chakraborty, Shreyasee; Yang, Jun J; Edelmann, Lisa; Schadt, Eric E; Korlach, Jonas; Scott, Stuart A

Molecular basis of ETV6-mediated predisposition to childhood acute lymphoblastic leukemia

ETV6介导的儿童急性淋巴细胞白血病易感性的分子基础

Nishii, Rina; Baskin-Doerfler, Rebekah; Yang, Wentao; Oak, Ninad; Zhao, Xujie; Yang, Wenjian; Hoshitsuki, Keito; Bloom, Mackenzie; Verbist, Katherine; Burns, Melissa; Li, Zhenhua; Lin, Ting-Nien; Qian, Maoxiang; Moriyama, Takaya; Gastier-Foster, Julie M; Rabin, Karen R; Raetz, Elizabeth; Mullighan, Charles; Pui, Ching-Hon; Yeoh, Allen Eng-Juh; Zhang, Jinghui; Metzger, Monika L; Klco, Jeffery M; Hunger, Stephen P; Newman, Scott; Wu, Gang; Loh, Mignon L; Nichols, Kim E; Yang, Jun J

Mechanistic studies of PEG-asparaginase-induced liver injury and hepatic steatosis in mice

小鼠PEG-天冬酰胺酶诱导肝损伤和肝脂肪变性的机制研究

Kumar, Gundala Venkata Naveen; Hoshitsuki, Keito; Rathod, Sanjay; Ramsey, Manda J; Kokai, Lauren; Kershaw, Erin E; Xie, Wen; Fernandez, Christian A