Hotta Akitsu相关文献与解析，生知库 | 链接生命科学的每一步

An iPSC-based in vitro model recapitulates human thymic epithelial development and multi-lineage specification

基于诱导多能干细胞的体外模型能够重现人类胸腺上皮发育和多谱系分化过程。

Pretemer, Yann; Gao, Yuxian; Kanai, Kaho; Yamamoto, Takuya; Kometani, Kohei; Ozaki, Manami; Nishigishi, Karin; Ikeda, Tadashi; Xu, Huaigeng; Hotta, Akitsu; Hamazaki, Yoko

细胞生物学

CCL5 paradoxically regulates glomerular injury by skewing macrophage polarization

CCL5通过改变巨噬细胞极化状态，以矛盾的方式调节肾小球损伤

期刊:JCI Insight

影响因子:6.1

doi:10.1172/jci.insight.173742

Kadariswantiningsih, Ika N; Okunaga, Issei; Yamasaki, Kaho; Empitu, Maulana A; Yamada, Hiroyuki; Makino, Shin-Ichi; Hotta, Akitsu; Yagita, Hideo; Aizawa, Masashi; Koyama-Nasu, Ryo; Kimura, Motoko Y; Tatsumoto, Narihito; Asanuma, Katsuhiko

Combined rapamycin and mesenchymal stem/stromal cells derived from induced pluripotent stem cells-mediated delivery of ACVR2B-Fc fusion protein reduces heterotopic ossification in a mouse model of fibrodysplasia ossificans progressiva.

雷帕霉素与源自诱导多能干细胞的间充质干/基质细胞联合递送 ACVR2B-Fc 融合蛋白，可减少进行性骨化性纤维发育不良小鼠模型中的异位骨化

期刊:JBMR Plus

影响因子:2.4

doi:10.1093/jbmrpl/ziaf068

Gao Pan, Inada Yoshiko, LÃ³pez-Iniesta Maria JosÃ©, Zhao Chengzhu, Goto Megumi, Hotta Akitsu, Sakurai Hidetoshi, Ikeya Makoto

iPSC-derived type IV collagen α5-expressing kidney organoids model Alport syndrome

iPSC衍生的表达IV型胶原α5的肾脏类器官模型Alport综合征

期刊:Communications Biology

影响因子:5.1

doi:10.1038/s42003-023-05203-4

Hirayama, Ryuichiro; Toyohara, Kosuke; Watanabe, Kei; Otsuki, Takeya; Araoka, Toshikazu; Mae, Shin-Ichi; Horinouchi, Tomoko; Yamamura, Tomohiko; Okita, Keisuke; Hotta, Akitsu; Iijima, Kazumoto; Nozu, Kandai; Osafune, Kenji

3D/类器官

发表日期：2023

文献求助收藏

Establishment of quantitative and consistent in vitro skeletal muscle pathological models of myotonic dystrophy type 1 using patient-derived iPSCs

利用患者来源的诱导多能干细胞建立定量且一致的1型强直性肌营养不良症体外骨骼肌病理模型

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-022-26614-z

Kawada, Ryu; Jonouchi, Tatsuya; Kagita, Akihiro; Sato, Masae; Hotta, Akitsu; Sakurai, Hidetoshi

Direct visualization of the transition status during neural differentiation by dual-fluorescent reporter human pluripotent stem cells

利用双荧光报告基因人多能干细胞直接观察神经分化过程中的转变状态

期刊:Stem Cell Reports

影响因子:5.1

doi:10.1016/j.stemcr.2022.07.001

Park, Gwanghyun; Shin, Minkyung; Lee, Wonyoung; Hotta, Akitsu; Kobayashi, Taeko; Kosodo, Yoichi

Characterization of hiPSC-Derived Muscle Progenitors Reveals Distinctive Markers for Myogenic Cell Purification Toward Cell Therapy

hiPSC衍生肌肉祖细胞的表征揭示了肌源性细胞纯化的独特标记，有望用于细胞治疗

期刊:Stem Cell Reports

影响因子:5.1

doi:10.1016/j.stemcr.2021.03.004

Nalbandian, Minas; Zhao, Mingming; Sasaki-Honda, Mitsuru; Jonouchi, Tatsuya; Lucena-Cacace, Antonio; Mizusawa, Takuma; Yasuda, Masahiko; Yoshida, Yoshinori; Hotta, Akitsu; Sakurai, Hidetoshi

细胞生物学

发表日期：2021

文献求助收藏

Development of alternative gene transfer techniques for ex vivo and in vivo gene therapy in a canine model

犬模型中用于体外和体内基因治疗的替代基因转移技术开发

期刊:Regenerative Therapy

影响因子:3.5

doi:10.1016/j.reth.2021.08.009

Noda, Masashi; Tatsumi, Kohei; Matsui, Hideto; Matsunari, Yasunori; Sato, Takeshi; Fukuoka, Yasushi; Hotta, Akitsu; Okano, Teruo; Kichikawa, Kimihiko; Sugimoto, Mitsuhiko; Shima, Midori; Nishio, Kenji

基因治疗

发表日期：2021

文献求助收藏

Induced Fetal Human Muscle Stem Cells with High Therapeutic Potential in a Mouse Muscular Dystrophy Model

诱导产生的胎儿人肌肉干细胞在小鼠肌肉萎缩症模型中展现出较高的治疗潜力

期刊:Stem Cell Reports

影响因子:5.1

doi:10.1016/j.stemcr.2020.06.004

Zhao, Mingming; Tazumi, Atsutoshi; Takayama, Satoru; Takenaka-Ninagawa, Nana; Nalbandian, Minas; Nagai, Miki; Nakamura, Yumi; Nakasa, Masanori; Watanabe, Akira; Ikeya, Makoto; Hotta, Akitsu; Ito, Yuta; Sato, Takahiko; Sakurai, Hidetoshi

AMPK-p38 axis converts human pluripotent stem cells to naive state

AMPK-p38轴将人类多能干细胞转化为原始状态

An iPSC-based in vitro model recapitulates human thymic epithelial development and multi-lineage specification

基于诱导多能干细胞的体外模型能够重现人类胸腺上皮发育和多谱系分化过程。

CCL5 paradoxically regulates glomerular injury by skewing macrophage polarization

CCL5通过改变巨噬细胞极化状态，以矛盾的方式调节肾小球损伤

Combined rapamycin and mesenchymal stem/stromal cells derived from induced pluripotent stem cells-mediated delivery of ACVR2B-Fc fusion protein reduces heterotopic ossification in a mouse model of fibrodysplasia ossificans progressiva.

雷帕霉素与源自诱导多能干细胞的间充质干/基质细胞联合递送 ACVR2B-Fc 融合蛋白，可减少进行性骨化性纤维发育不良小鼠模型中的异位骨化

iPSC-derived type IV collagen α5-expressing kidney organoids model Alport syndrome

iPSC衍生的表达IV型胶原α5的肾脏类器官模型Alport综合征

Establishment of quantitative and consistent in vitro skeletal muscle pathological models of myotonic dystrophy type 1 using patient-derived iPSCs

利用患者来源的诱导多能干细胞建立定量且一致的1型强直性肌营养不良症体外骨骼肌病理模型

Direct visualization of the transition status during neural differentiation by dual-fluorescent reporter human pluripotent stem cells

利用双荧光报告基因人多能干细胞直接观察神经分化过程中的转变状态

Characterization of hiPSC-Derived Muscle Progenitors Reveals Distinctive Markers for Myogenic Cell Purification Toward Cell Therapy

hiPSC衍生肌肉祖细胞的表征揭示了肌源性细胞纯化的独特标记，有望用于细胞治疗

Development of alternative gene transfer techniques for ex vivo and in vivo gene therapy in a canine model

犬模型中用于体外和体内基因治疗的替代基因转移技术开发

Induced Fetal Human Muscle Stem Cells with High Therapeutic Potential in a Mouse Muscular Dystrophy Model

诱导产生的胎儿人肌肉干细胞在小鼠肌肉萎缩症模型中展现出较高的治疗潜力