日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The fast-evolving FIKK kinase family of Plasmodium falciparum can be inhibited by a single compound.

恶性疟原虫快速进化的 FIKK 激酶家族可被单一化合物抑制

Belda Hugo, Bradley David, Christodoulou Evangelos, Nofal Stephanie D, Broncel Malgorzata, Jones David, Davies Heledd, Bertran M Teresa, Purkiss Andrew G, Ogrodowicz Roksana W, Joshi Dhira, O'Reilly Nicola, Walport Louise, Powell Andrew, House David, Kjaer Svend, Claessens Antoine, Landry Christian R, Treeck Moritz

Conformational dynamics of the bacterial E3 ligase SspH1

细菌E3连接酶SspH1的构象动力学

Kennedy, Cassandra R; Esposito, Diego; Huber, Jessica; House, David; Rittinger, Katrin

Mpox lesion counting with semantic and instance segmentation methods

利用语义分割和实例分割方法进行MPOX病灶计数

Jiang, Bohan; McNeil, Andrew J; Liu, Yihao; House, David W; Mbala-Kingebeni, Placide; Mbaya, Olivier Tshiani; Silaphet, Tyra; Dodd, Lori E; Cowen, Edward W; Nussenblatt, Veronique; Bonnett, Tyler; Chen, Ziche; Saknite, Inga; Dawant, Benoit M; Tkaczyk, Eric R

Profiling Sulfur(VI) Fluorides as Reactive Functionalities for Chemical Biology Tools and Expansion of the Ligandable Proteome

将六价硫氟化物作为化学生物学工具的反应性功能基团进行分析,并扩展可配体结合的蛋白质组。

Gilbert, Katharine E; Vuorinen, Aini; Aatkar, Arron; Pogány, Peter; Pettinger, Jonathan; Grant, Emma K; Kirkpatrick, Joanna M; Rittinger, Katrin; House, David; Burley, Glenn A; Bush, Jacob T

Efficient Ligand Discovery Using Sulfur(VI) Fluoride Reactive Fragments

利用硫(VI)氟化物反应片段进行高效配体发现

Aatkar, Arron; Vuorinen, Aini; Longfield, Oliver E; Gilbert, Katharine; Peltier-Heap, Rachel; Wagner, Craig D; Zappacosta, Francesca; Rittinger, Katrin; Chung, Chun-Wa; House, David; Tomkinson, Nicholas C O; Bush, Jacob T

Reactive fragments targeting carboxylate residues employing direct to biology, high-throughput chemistry

利用直接生物学、高通量化学方法靶向羧酸残基的反应性片段

Thomas, Ross P; Grant, Emma K; Dickinson, Eleanor R; Zappacosta, Francesca; Edwards, Lee J; Hann, Michael M; House, David; Tomkinson, Nicholas C O; Bush, Jacob T

Publisher Correction: MOG analogues to explore the MCT2 pharmacophore, α-ketoglutarate biology and cellular effects of N-oxalylglycine

出版商更正:MOG类似物用于探索MCT2药效团、α-酮戊二酸生物学以及N-草酰甘氨酸的细胞效应

Fets, Louise; Bevan, Natalie; Nunes, Patrícia M; Campos, Sebastien; Dos Santos, Mariana Silva; Sherriff, Emma; MacRae, James I; House, David; Anastasiou, Dimitrios

A direct-to-biology high-throughput chemistry approach to reactive fragment screening

一种直接应用于生物体的高通量化学方法,用于反应片段筛选

Thomas, Ross P; Heap, Rachel E; Zappacosta, Francesca; Grant, Emma K; Pogány, Peter; Besley, Stephen; Fallon, David J; Hann, Michael M; House, David; Tomkinson, Nicholas C O; Bush, Jacob T

Assaying kinase activity of the TPL-2/NF-κB1 p105/ABIN-2 complex using an optimal peptide substrate

使用最佳肽底物测定TPL-2/NF-κB1 p105/ABIN-2复合物的激酶活性

Kümper, Sandra; Gantke, Thorsten; Chen, Chao-Sheng; Soneji, Yasmina; Pattison, Michael J; Chakravarty, Probir; Kjær, Svend; Thomas, Daniel; Haslam, Carl; Leavens, Bill J; House, David; Powell, David J; Ley, Steven C

Injectable silk-based biomaterials for cervical tissue augmentation: an in vitro study

可注射丝基生物材料用于宫颈组织增强:一项体外研究

Joseph E Brown, Benjamin P Partlow, Alison M Berman, Michael D House, David L Kaplan