日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A rare genetic variant confers resistance to neurodegeneration across multiple neurological disorders by augmenting selective autophagy.

一种罕见的基因变异通过增强选择性自噬,赋予多种神经系统疾病对神经退行性疾病的抵抗力。

Croce Katherine R, Ng Christopher, Pankiv Serihy, Albarran Eddy, Langfelder Peter, Ramos de Jesus Ana, Duncan Glenn M, Wang Nan, Basile Anna, McHugh Caitlin, Litt Nicole A, Li Alina, Friedman Sophia, Cortes Etty P, Zody Michael C, Yang X William, Ding Jun B, Vonsattel Jean Paul G, Simonsen Anne, Housman David E, Wexler Nancy S, Yamamoto Ai

CellPHIE: Integrating Pathway Discovery With Pooled Profiling of Perturbations Uncovers Pathways of Huntington's Disease, Including Genetic Modifiers of Neuronal Development and Morphology.

CellPHIE:将通路发现与扰动汇总分析相结合,揭示了亨廷顿病的通路,包括神经元发育和形态的遗传修饰因子

Kang Byunguk, Murphy Michael, Ng Christopher W, Leventhal Matthew Joseph, Huynh Nhan, Im Egun, Danquah Serwah, Housman David E, Nehme Ralda, Farhi Samouil L, Fraenkel Ernest

Striatal transcriptome changes linked to drug-induced repetitive behaviors.

纹状体转录组变化与药物诱发的重复行为有关

Crittenden Jill R, Gipson Theresa A, Smith Anne C, Bowden Hilary A, Yildirim Ferah, Fischer Kyle B, Yim Michael, Housman David E, Graybiel Ann M

Detection of long repeat expansions from PCR-free whole-genome sequence data

利用无PCR全基因组测序数据检测长重复序列扩增

Dolzhenko, Egor; van Vugt, Joke J F A; Shaw, Richard J; Bekritsky, Mitchell A; van Blitterswijk, Marka; Narzisi, Giuseppe; Ajay, Subramanian S; Rajan, Vani; Lajoie, Bryan R; Johnson, Nathan H; Kingsbury, Zoya; Humphray, Sean J; Schellevis, Raymond D; Brands, William J; Baker, Matt; Rademakers, Rosa; Kooyman, Maarten; Tazelaar, Gijs H P; van Es, Michael A; McLaughlin, Russell; Sproviero, William; Shatunov, Aleksey; Jones, Ashley; Al Khleifat, Ahmad; Pittman, Alan; Morgan, Sarah; Hardiman, Orla; Al-Chalabi, Ammar; Shaw, Chris; Smith, Bradley; Neo, Edmund J; Morrison, Karen; Shaw, Pamela J; Reeves, Catherine; Winterkorn, Lara; Wexler, Nancy S; Housman, David E; Ng, Christopher W; Li, Alina L; Taft, Ryan J; van den Berg, Leonard H; Bentley, David R; Veldink, Jan H; Eberle, Michael A

HSF1-dependent and -independent regulation of the mammalian in vivo heat shock response and its impairment in Huntington's disease mouse models

HSF1依赖性和非依赖性哺乳动物体内热休克反应的调控及其在亨廷顿病小鼠模型中的受损

Neueder, Andreas; Gipson, Theresa A; Batterton, Sophie; Lazell, Hayley J; Farshim, Pamela P; Paganetti, Paolo; Housman, David E; Bates, Gillian P

Genome Sequencing Technologies and Nursing: What Are the Roles of Nurses and Nurse Scientists?

基因组测序技术与护理:护士和护理科学家的角色是什么?

Taylor, Jacquelyn Y; Wright, Michelle L; Hickey, Kathleen T; Housman, David E

Systematic identification of combinatorial drivers and targets in cancer cell lines

系统性鉴定癌细胞系中的组合驱动因子和靶点

Tabchy, Adel; Eltonsy, Nevine; Housman, David E; Mills, Gordon B

Gene expression studies for the analysis of domoic acid production in the marine diatom Pseudo-nitzschia multiseries

海洋硅藻多系列拟菱形藻中软骨藻酸产生的基因表达研究

Boissonneault, Katie Rose; Henningsen, Brooks M; Bates, Stephen S; Robertson, Deborah L; Milton, Sean; Pelletier, Jerry; Hogan, Deborah A; Housman, David E

Dysregulation of dopamine receptor D2 as a sensitive measure for Huntington disease pathology in model mice

多巴胺受体D2失调可作为亨廷顿病模型小鼠病理的敏感指标

Crook, Zachary R; Housman, David E

CalDAG-GEFI down-regulation in the striatum as a neuroprotective change in Huntington's disease

亨廷顿病中纹状体CalDAG-GEFI下调是一种神经保护性改变

Crittenden, Jill R; Dunn, Denise E; Merali, Farhan I; Woodman, Ben; Yim, Michael; Borkowska, Anna E; Frosch, Matthew P; Bates, Gillian P; Housman, David E; Lo, Donald C; Graybiel, Ann M