日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A scalable step count-based predictor of biological age: development and validation of MoveIt! Age in community-dwelling adults and geriatric rehabilitation inpatients

基于步数的可扩展生物年龄预测器:MoveIt! Age 在社区居住成年人和老年康复住院患者中的开发和验证

Lu, Jessica K; Wang, Weilan; Guan, Lihuan; van der Velde, Jeroen; Hoeks, Joris; Schrauwen, Patrick; Salomons, Gajja S; Houtkooper, Riekelt H; Maier, Andrea B; Janssens, Georges E

Reduced Versus Oxidized NAD(+) Precursors Drive Distinct Transcriptomic, Proteomic, and Metabolic Profiles in Hepatocytes

还原型与氧化型 NAD(+) 前体驱动肝细胞中不同的转录组、蛋白质组和代谢谱

Vinten, Kasper T; Schomakers, Bauke V; Denis, Simone; van Weeghel, Michel; Jongejan, Aldo; Ofman, Rob; Piersma, Sander R; Jimenez, Connie R; Janssens, Georges E; Zapata-Pérez, Rubén; Houtkooper, Riekelt H

Ex-vivo culture of human hypertrophic cardiomyopathy hearts: Functional and metabolic changes during long-term culture.

人类肥厚型心肌病心脏的体外培养:长期培养过程中的功能和代谢变化。

Nassar Ali, Warnaar Vincent A J, Duursma Inez, Schomakers Bauke V, Chaami Chahida, Ochala Julien, van Weeghel Michel, Houtkooper Riekelt H, Michels Michelle, Dendorfer Andreas, Kuster Diederik W D, van der Velden Jolanda

Aminoacyl-tRNA Synthetases: Variant Classification, Functional Assays, and Emerging Therapeutic Strategies

氨酰tRNA合成酶:变体分类、功能分析和新兴治疗策略

Mendes, M I; Smith, D E; Spek, V; Bosch, A M; Corpeleijn, W E; Engelen, M; Fuchs, S A; Hadchouel, A; Heinemann, I U; Houtkooper, R H; Hoytema van Konijnenburg, E M M; Kemp, S; Langeveld, M; Karnebeek, C D M; Pop, A; Siu, V M; Wolf, N I; Salomons, G S

HEPES in Cell Culture Alters the Multi-Omics Profile Exhibited by Gaucher Disease Fibroblasts

HEPES在细胞培养中改变了戈谢病成纤维细胞的多组学特征

Corazolla, Eleonore M; Schomakers, Bauke V; Trętowicz, Maria M; Hermans, Jill; van Weeghel, Michel; Vaz, Frédéric M; Pras-Raves, Mia L; Vlugt, Karen Ghauharali-van der; Beers-Stet, Femke S; Goorden, Susanna M I; Jansen-Meijer, Judith; Janssens, Georges E; Hollak, Carla E M; Houtkooper, Riekelt H; van Kuilenburg, André B P

Reduced levels of mitochondrial ribosomal protein MRPL54 does not alter Apc related adenoma formation

线粒体核糖体蛋白MRPL54水平降低并不影响Apc相关腺瘤的形成。

Spaan, Claudia N; Daniels, Eileen; Smit, Wouter L; de Boer, Ruben J; Silva, Joana; Vermeulen, Jacqueline L M; Meisner, S; Muncan, Vanesa; Houtkooper, Riekelt H; Heijmans, Jarom

ACMSD inhibition corrects fibrosis, inflammation, and DNA damage in MASLD/MASH.

ACMSD 抑制剂可纠正 MASLD/MASH 中的纤维化、炎症和 DNA 损伤

Liu Yasmine J, Kimura Masaki, Li Xiaoxu, Sulc Jonathan, Wang Qi, Rodríguez-López Sandra, Scantlebery Angelique M L, Strotjohann Keno, Gallart-Ayala Hector, Vijayakumar Archana, Myers Robert P, Ivanisevic Julijana, Houtkooper Riekelt H, Subramanian G Mani, Takebe Takanori, Auwerx Johan

A lysosomal surveillance response to stress extends healthspan

溶酶体对压力的监视反应可延长健康寿命

Terytty Yang Li # ,Arwen W Gao # ,Rendan Yang # ,Yu Sun # ,Yuxuan Lei ,Xiaoxu Li ,Lin Chen ,Yasmine J Liu ,Rachel N Arey ,Kimberly Morales ,Raya B Liu ,Wenzheng Wang ,Ang Zhou ,Tong-Jin Zhao ,Weisha Li ,Amélia Lalou ,Qi Wang ,Tanes Lima ,Riekelt H Houtkooper ,Johan Auwerx

Immuno-metabolic stress responses control longevity from mitochondrial translation inhibition in C. elegans

秀丽隐杆线虫中,免疫代谢应激反应通过抑制线粒体翻译来控制寿命。

Hu, Iman Man; Molenaars, Marte; Jaspers, Yorrick R J; Schomakers, Bauke V; van Weeghel, Michel; Bakker, Amber; Modder, Melanie; Dewulf, Joseph P; Bommer, Guido T; Gao, Arwen W; Janssens, Georges E; Houtkooper, Riekelt H

Integrated multi-omics mapping of mitochondrial dysfunction and substrate preference in Barth syndrome cardiac tissue

巴特综合征心脏组织线粒体功能障碍和底物偏好的整合多组学分析

Schomakers, Bauke V; Passadouro, Adriana S; Trętowicz, Maria M; Simpson, Pelle J; Jaspers, Yorrick R J; van Weeghel, Michel; Hu, Iman Man; Lamboo, Cathelijne M E; Cloutier, Denise; Byrne, Barry J; van Klinken, Jan Bert; Janssen, Paul M L; Piersma, Sander R; Jimenez, Connie R; Vaz, Frédéric M; Salomons, Gajja S; van der Velden, Jolanda; Houtkooper, Riekelt H; Mosegaard, Signe