日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

BCMA-directed mRNA CAR T cell therapy for myasthenia gravis: a randomized, double-blind, placebo-controlled phase 2b trial

BCMA靶向mRNA CAR T细胞疗法治疗重症肌无力：一项随机、双盲、安慰剂对照的2b期试验

期刊:Nature Medicine
影响因子:50
doi:10.1038/s41591-025-04171-y
Vu, Tuan; Durmus, Hacer; Rivner, Michael; Shroff, Sheetal; Ragole, Thomas; Myers, Bennett; Pasnoor, Mamatha; Small, George; Karam, Chafic; Vullaganti, Mithila; Peltier, Amanda; Sahagian, Gregory; Feinberg, Marc H; Slanksy, Adam; Barnett-Tapia, Carolina; Siddiqi, Zaeem; Gwathmey, Kelly; Badruddoja, Michael A; Kamboh, Hafsa; Ruggerie, Rachel N; Fedak, Renee R; Stewart, C Andrew; Kurtoglu, Metin; Kalayoglu, Murat; Singer, Michael; Jewell, Christopher M; Miljkovic, Milos D; Dimachkie, Mazen; Mozaffar, Tahseen; Howard, James F Jr
T细胞
重症肌无力
T细胞
细胞生物学
免疫/内分泌
发表日期：2026
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BCMA-directed mRNA CAR-T cell therapy for myasthenia gravis: exploratory biomarker analysis of a placebo-controlled phase 2b trial.

BCMA 靶向 mRNA CAR-T 细胞疗法治疗重症肌无力：安慰剂对照 2b 期试验的探索性生物标志物分析。

期刊:Nature Medicine
影响因子:50
doi:10.1038/s41591-025-04170-z
Fedak Renee R, Ruggerie Rachel N, Shan Yufei, Curvino Elizabeth J, de Sousa Juliana F, Daniel Shaji, Ngo-Casi Minhtran, Kamboh Hafsa, Vu Tuan, Durmuş Hacer, Mozaffar Tahseen, Howard James F Jr, English Emily P, Benson Albina, Duvernay Matthew T, Singer Michael S, Kalayoglu Murat V, Brunn Carsten, Bodansky Aaron, Anderson Mark S, DeRisi Joseph L, Garcia Samantha T, Yu David J L, Zorn Kelsey C, Kurtoglu Metin, Miljković Miloš D, Stewart C Andrew, Jewell Christopher M
细胞生物学
T细胞
重症肌无力
免疫/内分泌
发表日期：2026
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Efficacy and Safety of Vemircopan in Generalized Myasthenia Gravis: A Randomized Clinical Trial

维米尔可泮治疗全身型重症肌无力的疗效和安全性：一项随机临床试验

期刊:Jama Neurology
影响因子:21.3
doi:10.1001/jamaneurol.2026.0902
Saccà, Francesco; Gialdini, Gino; Howard, James F Jr; Vu, Tuan H; Meisel, Andreas; Peric, Stojan; Lünemann, Jan D; Sgarzi, Manlio; Shaibani, Aziz; Bril, Vera; Yeh, Jiann-Horng; Reyes-Garrido, Virginia; Liao, Serena; Metais, Camille; van der Valk, Ralf J P
免疫/内分泌
重症肌无力
发表日期：2026
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Advancing Care in Myasthenia Gravis: What Can We Learn From the Multiple Sclerosis Community?

推进重症肌无力患者的治疗：我们可以从多发性硬化症领域学到什么？

期刊:Neurology and Therapy
影响因子:4.8
doi:10.1007/s40120-025-00851-6
Howard, James F Jr; Sadeghian, Mona; Savic, Natasa; Giovannoni, Gavin
重症肌无力
神经科学
多发性硬化症
免疫/内分泌
发表日期：2026
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Minimal Symptom Expression in Generalized Myasthenia Gravis: A Valuable Patient-Centric Treatment Goal

重症肌无力全身型患者的最小症状表现：以患者为中心的重要治疗目标

期刊:European Journal of Neurology
影响因子:3.9
doi:10.1111/ene.70563
Meisel, Andreas; Uzawa, Akiyuki; Qi, Cynthia Z; Nowacek, Dustin; Guptill, Jeff; Howard, James F Jr
重症肌无力
免疫/内分泌
发表日期：2026
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Patient Outcomes Among Medicare Beneficiaries With Guillain-Barré Syndrome

患有格林-巴利综合征的医疗保险受益人的患者预后

期刊:Journal of the Peripheral Nervous System
影响因子:3.2
doi:10.1111/jns.70094
Wright, Brad; Eiffert, Samantha R; Cirincione, Abagail; Nardin, Joshua; Howard, James F Jr; Traub, Rebecca E
发表日期：2026
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Changes in corticosteroid and non-steroidal immunosuppressive therapy with long-term zilucoplan treatment in generalized myasthenia gravis

长期使用齐鲁普兰治疗全身型重症肌无力时，皮质类固醇和非甾体类免疫抑制剂治疗方案的变化

期刊:Journal of Neurology
影响因子:4.6
doi:10.1007/s00415-025-13113-0
Hewamadduma, Channa; Freimer, Miriam; Genge, Angela; Leite, M Isabel; Utsugisawa, Kimiaki; Vu, Tuan; Boroojerdi, Babak; Grimson, Fiona; Savic, Natasa; Vanderkelen, Mark; Howard, James F Jr
重症肌无力
免疫/内分泌
发表日期：2025
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Switching to subcutaneous zilucoplan from intravenous complement component 5 inhibitors in generalised myasthenia gravis: a phase IIIb, open-label study

在全身型重症肌无力患者中，从静脉注射补体成分 5 抑制剂转换为皮下注射齐鲁可普兰：一项 IIIb 期开放标签研究

期刊:Therapeutic Advances in Neurological Disorders
影响因子:4.1
doi:10.1177/17562864251347283
Freimer, Miriam; Desai, Urvi; Govindarajan, Raghav; Kang, Min K; Khan, Shaida; Khatri, Bhupendra; Levine, Todd; Macwan, Samir; Shieh, Perry B; Weiss, Michael D; Bloemers, Jos; Boroojerdi, Babak; Delicha, Eumorphia Maria; Lavrov, Andreea; Singh, Puneet; Howard, James F Jr
重症肌无力
免疫/内分泌
发表日期：2025
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Appropriate use of steroids for patients with generalized Myasthenia Gravis: an international Delphi study

类固醇在全身型重症肌无力患者中的合理应用：一项国际德尔菲研究

期刊:Therapeutic Advances in Neurological Disorders
影响因子:4.1
doi:10.1177/17562864251398375
Wiendl, Heinz; Murai, Hiroyuki; Narayanaswami, Pushpa; Saccà, Francesco; Silvestri, Nicholas J; Howard, James F Jr
重症肌无力
免疫/内分泌
发表日期：2025
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Long-Term Efficacy and Safety of Ravulizumab in Adults With Anti-Acetylcholine Receptor Antibody-Positive Generalized Myasthenia Gravis: Final Results From the Phase 3 CHAMPION MG Open-Label Extension

拉武利珠单抗治疗抗乙酰胆碱受体抗体阳性的全身型重症肌无力成人患者的长期疗效和安全性：3期CHAMPION MG开放标签扩展研究的最终结果

期刊:European Journal of Neurology
影响因子:3.9
doi:10.1111/ene.70158
Vu, Tuan H; Mantegazza, Renato; Annane, Djillali; Katsuno, Masahisa; Meisel, Andreas; Nicolle, Michael W; Bril, Vera; Aguzzi, Rasha; Frick, Glen; Howard, James F Jr
信号转导
MPI
重症肌无力
免疫/内分泌
发表日期：2025
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