日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A Humanized Mouse Model Coupled with Computational Analysis Identifies Potent Glycolipid Agonist of Invariant NKT Cells

人源化小鼠模型结合计算分析鉴定出一种强效的不变NKT细胞糖脂激动剂

Saavedra-Avila, Noemi A; Pigni, Natalia B; Caldwell, Donald R; Chena-Becerra, Florencia; Intano, Jose Jr; Ng, Tony W; Chennamadhavuni, Divya; Porcelli, Steven A; Gascón, José A; Howell, Amy R

Easily accessible non-aromatic heterocycles with handles: 4-bromo-2,3-dihydrofurans from 1,2-dibromohomoallylic alcohols

易于合成的带把手的非芳香杂环化合物:由 1,2-二溴烯丙醇合成的 4-溴-2,3-二氢呋喃

An, Jason; Intano, Jose Jr; Richard, Alissa; Kim, Taehyun; Gascón, José A; Howell, Amy R

α-Methylene-β-Lactone Scaffold for Developing Chemical Probes at the Two Ends of the Selectivity Spectrum

α-亚甲基-β-内酯骨架用于开发选择性谱两端的化学探针

Wang, Lei; Riel, Louis P; Bajrami, Bekim; Deng, Bin; Howell, Amy R; Yao, Xudong

Chemical proteomic analysis of palmostatin beta-lactone analogs that affect N-Ras palmitoylation

对影响 N-Ras 棕榈酰化的棕榈抑素 β-内酯类似物进行化学蛋白质组学分析

Suciu, Radu M; Luvaga, Irungu K; Hazeen, Akram; Weerasooriya, Chulangani; Richardson, Stewart K; Firestone, Ari J; Shannon, Kevin; Howell, Amy R; Cravatt, Benjamin F

Amide-Linked C4″-Saccharide Modification of KRN7000 Provides Potent Stimulation of Human Invariant NKT Cells and Anti-Tumor Immunity in a Humanized Mouse Model.

KRN7000 的酰胺连接 C4'-糖修饰可在人源化小鼠模型中有效刺激人类不变 NKT 细胞和抗肿瘤免疫

Saavedra-Avila Noemi Alejandra, Keshipeddy Santosh, Guberman-Pfeffer Matthew J, Pérez-Gallegos Ayax, Saini Neeraj K, Schäfer Carolina, Carreño Leandro J, Gascón José A, Porcelli Steven A, Howell Amy R

Heterogeneous Catalytic Oxidation of Amides to Imides by Manganese Oxides

锰氧化物催化酰胺非均相氧化生成酰亚胺

Biswas, Sourav; Khanna, Harshul S; Nizami, Quddus A; Caldwell, Donald R; Cavanaugh, Katherine T; Howell, Amy R; Raman, Sumathy; Suib, Steven L; Nandi, Partha

Pd-Catalyzed Acyl C-O Bond Activation for Selective Ring-Opening of α-Methylene-β-lactones with Amines

钯催化酰基CO键活化用于胺类化合物选择性开环α-亚甲基-β-内酯

Malapit, Christian A; Caldwell, Donald R; Sassu, Nicole; Milbin, Samuel; Howell, Amy R

Rh-Catalyzed Conjugate Addition of Aryl and Alkenyl Boronic Acids to α-Methylene-β-lactones: Stereoselective Synthesis of trans-3,4-Disubstituted β-Lactones

铑催化芳基硼酸和烯基硼酸与α-亚甲基-β-内酯的共轭加成反应:反式-3,4-二取代β-内酯的立体选择性合成

Malapit, Christian A; Luvaga, Irungu K; Caldwell, Donald R; Schipper, Nicholas K; Howell, Amy R

Contact sensitizers trigger human CD1-autoreactive T-cell responses.

接触致敏剂可触发人类 CD1 自身反应性 T 细胞反应

Betts Richard J, Perkovic Adrijana, Mahapatra Subhashree, Del Bufalo Aurélia, Camara Kaddy, Howell Amy R, Martinozzi Teissier Silvia, De Libero Gennaro, Mori Lucia

Atypical natural killer T-cell receptor recognition of CD1d-lipid antigens

非典型自然杀伤T细胞受体识别CD1d-脂质抗原

Le Nours, Jérôme; Praveena, T; Pellicci, Daniel G; Gherardin, Nicholas A; Ross, Fiona J; Lim, Ricky T; Besra, Gurdyal S; Keshipeddy, Santosh; Richardson, Stewart K; Howell, Amy R; Gras, Stephanie; Godfrey, Dale I; Rossjohn, Jamie; Uldrich, Adam P