日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Inhibition of GCKIII kinases STK25 and MST3 mitigates organ lipotoxicity and enhances metabolic resilience under nutritional stress

抑制GCKIII激酶STK25和MST3可减轻器官脂毒性,并增强营养应激下的代谢韧性。

Andersson, Emma; Gongye, Xiangdong; Cansby, Emmelie; Zhang, Jingjing; Caputo, Mara; Asiedu, Bernice; Garellick, Viktor; Booten, Sheri; Murray, Sue; Font-Gironès, Ferran; Ruud, Johan; Lind, Dan Emil; Amrutkar, Manoj; Howell, Brian W; Wernstedt Asterholm, Ingrid; Mahlapuu, Margit

Whole genome analysis in APOE4 homozygotes identifies the DAB1-RELN pathway in Alzheimer's disease pathogenesis

对 APOE4 纯合子的全基因组分析揭示了 DAB1-RELN 通路在阿尔茨海默病发病机制中的作用

Bracher-Smith, Matthew; Leonenko, Ganna; Baker, Emily; Crawford, Karen; Graham, Andrew C; Salih, Dervis A; Howell, Brian W; Hardy, John; Escott-Price, Valentina

Ethanol Exposure Transiently Elevates but Persistently Inhibits Tyrosine Kinase Activity and Impairs the Growth of the Nascent Apical Dendrite

乙醇暴露会短暂升高酪氨酸激酶活性,但持续抑制其活性,并损害新生顶端树突的生长。

Wang, Dandan; Enck, Joshua; Howell, Brian W; Olson, Eric C

RELN Mutations in Autism Spectrum Disorder

自闭症谱系障碍中的RELN基因突变

Lammert, Dawn B; Howell, Brian W

Role of the postnatal radial glial scaffold for the development of the dentate gyrus as revealed by Reelin signaling mutant mice.

通过 Reelin 信号突变小鼠揭示出生后放射状胶质支架在齿状回发育中的作用

Brunne Bianka, Franco Santos, Bouché Elisabeth, Herz Joachim, Howell Brian W, Pahle Jasmine, Müller Ulrich, May Petra, Frotscher Michael, Bock Hans H

Reelin and stk25 have opposing roles in neuronal polarization and dendritic Golgi deployment

Reelin 和 stk25 在神经元极化和树突高尔基体部署中发挥着相反的作用。

Matsuki, Tohru; Matthews, Russell T; Cooper, Jonathan A; van der Brug, Marcel P; Cookson, Mark R; Hardy, John A; Olson, Eric C; Howell, Brian W

Interaction of reelin with amyloid precursor protein promotes neurite outgrowth.

reelin 与淀粉样前体蛋白的相互作用促进神经突生长

Hoe Hyang-Sook, Lee Kea Joo, Carney Rosalind S E, Lee Jiyeon, Markova Alexandra, Lee Ji-Yun, Howell Brian W, Hyman Bradley T, Pak Daniel T S, Bu Guojun, Rebeck G William

Regulation of endosomal motility and degradation by amyotrophic lateral sclerosis 2/alsin

肌萎缩侧索硬化症2/alsin对内体运动和降解的调控

Lai, Chen; Xie, Chengsong; Shim, Hoon; Chandran, Jayanth; Howell, Brian W; Cai, Huaibin

Reduction of Crk and CrkL expression blocks reelin-induced dendritogenesis

Crk 和 CrkL 表达的降低会阻断 reelin 诱导的树突生成。

Matsuki, Tohru; Pramatarova, Albéna; Howell, Brian W

Mouse disabled 1 regulates the nuclear position of neurons in a Drosophila eye model

小鼠disabled 1调控果蝇眼模型中神经元的核定位

Pramatarova, Albéna; Ochalski, Pawel G; Lee, Chi-Hon; Howell, Brian W