日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Sterol imbalances and cholesterol-24-hydroxylase dysregulation is linked to the underlying progression of multiple sclerosis

甾醇失衡和胆固醇-24-羟化酶失调与多发性硬化症的潜在进展有关

Griffiths, Lauren; Hawkins, Kristen; Yutuc, Eylan; Angelini, Roberto; Fosuah, Racheal; Pacciarini, Manuela; Dickson, Alison; Robertson, Neil; Childs, Laura; Loveless, Samantha; Tallantyre, Emma; Griffiths, William J; Wang, Yuqin; Howell, Owain W

A Review of Compartmentalised Inflammation and Tertiary Lymphoid Structures in the Pathophysiology of Multiple Sclerosis

多发性硬化症病理生理学中分隔性炎症和三级淋巴结构的综述

Kee, Rachael; Naughton, Michelle; McDonnell, Gavin V; Howell, Owain W; Fitzgerald, Denise C

The association between neurodegeneration and local complement activation in the thalamus to progressive multiple sclerosis outcome

丘脑神经退行性变与局部补体激活和进行性多发性硬化症预后之间的关联

Cooze, Benjamin J; Dickerson, Matthew; Loganathan, Rukshikah; Watkins, Lewis M; Grounds, Ethan; Pearson, Ben R; Bevan, Ryan Jack; Morgan, B Paul; Magliozzi, Roberta; Reynolds, Richard; Neal, James W; Howell, Owain W

Visualizing Cholesterol in the Brain by On-Tissue Derivatization and Quantitative Mass Spectrometry Imaging

利用组织内衍生化和定量质谱成像技术可视化脑内胆固醇

Angelini, Roberto; Yutuc, Eylan; Wyatt, Mark F; Newton, Jillian; Yusuf, Fowzi A; Griffiths, Lauren; Cooze, Benjamin J; El Assad, Dana; Frache, Gilles; Rao, Wei; Allen, Luke B; Korade, Zeljka; Nguyen, Thu T A; Rathnayake, Rathnayake A C; Cologna, Stephanie M; Howell, Owain W; Clench, Malcolm R; Wang, Yuqin; Griffiths, William J

Metabolic profiling in serum, cerebrospinal fluid, and brain of patients with cerebrotendinous xanthomatosis

脑腱黄瘤病患者血清、脑脊液和脑组织的代谢谱分析

Höflinger, Philip; Hauser, Stefan; Yutuc, Eylan; Hengel, Holger; Griffiths, Lauren; Radelfahr, Florentine; Howell, Owain W; Wang, Yuqin; Connor, Sonja L; Duell, P Barton; DeBarber, Andrea E; Martus, Peter; Lütjohann, Dieter; Griffiths, William J; Schöls, Ludger

B cell rich meningeal inflammation associates with increased spinal cord pathology in multiple sclerosis.

B细胞丰富的脑膜炎症与多发性硬化症中脊髓病理的加重有关

Reali Camilla, Magliozzi Roberta, Roncaroli Federico, Nicholas Richard, Howell Owain W, Reynolds Richard

Complement is activated in progressive multiple sclerosis cortical grey matter lesions

补体在进行性多发性硬化症皮质灰质病变中被激活

Watkins, Lewis M; Neal, James W; Loveless, Sam; Michailidou, Iliana; Ramaglia, Valeria; Rees, Mark I; Reynolds, Richard; Robertson, Neil P; Morgan, B Paul; Howell, Owain W

Complement activation in multiple sclerosis plaques: an immunohistochemical analysis

多发性硬化斑块中补体激活:免疫组织化学分析

Ingram, Gillian; Loveless, Sam; Howell, Owain W; Hakobyan, Svetlana; Dancey, Bethan; Harris, Claire L; Robertson, Neil P; Neal, James W; Morgan, B Paul

New hyperekplexia mutations provide insight into glycine receptor assembly, trafficking, and activation mechanisms

新的惊厥症突变为甘氨酸受体的组装、转运和激活机制提供了新的见解

Bode, Anna; Wood, Sian-Elin; Mullins, Jonathan G L; Keramidas, Angelo; Cushion, Thomas D; Thomas, Rhys H; Pickrell, William O; Drew, Cheney J G; Masri, Amira; Jones, Elizabeth A; Vassallo, Grace; Born, Alfred P; Alehan, Fusun; Aharoni, Sharon; Bannasch, Gerald; Bartsch, Marius; Kara, Bulent; Krause, Amanda; Karam, Elie G; Matta, Stephanie; Jain, Vivek; Mandel, Hanna; Freilinger, Michael; Graham, Gail E; Hobson, Emma; Chatfield, Sue; Vincent-Delorme, Catherine; Rahme, Jubran E; Afawi, Zaid; Berkovic, Samuel F; Howell, Owain W; Vanbellinghen, Jean-François; Rees, Mark I; Chung, Seo-Kyung; Lynch, Joseph W

Activated microglia mediate axoglial disruption that contributes to axonal injury in multiple sclerosis

活化的微胶质细胞介导轴突胶质细胞破坏,从而导致多发性硬化症中的轴突损伤。

Howell, Owain W; Rundle, Jon L; Garg, Anurag; Komada, Masayuki; Brophy, Peter J; Reynolds, Richard