日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The utility of ctDNA in detecting minimal residual disease following curative surgery in colorectal cancer: a systematic review and meta-analysis

ctDNA在结直肠癌根治术后微小残留病灶检测中的应用:系统评价和荟萃分析

Faulkner, Lucy G; Howells, Lynne M; Pepper, Coral; Shaw, Jacqueline A; Thomas, Anne L

Clinical trials in cancer screening, prevention and early diagnosis (SPED): a systematic mapping review

癌症筛查、预防和早期诊断(SPED)临床试验:系统性综述

O'Dowd, Emma L; Merriel, Samuel W D; Cheng, Vinton W T; Khan, Sam; Howells, Lynne M; Gopal, Dipesh P; Roundhill, Elizabeth A; Brennan, Paul M; Crosbie, Philip A J; Neal, Richard D; Brown, Karen; Crosbie, Emma J; Baldwin, David R

Curcumin Combined with FOLFOX Chemotherapy Is Safe and Tolerable in Patients with Metastatic Colorectal Cancer in a Randomized Phase IIa Trial.

在一项随机 IIa 期试验中,姜黄素联合 FOLFOX 化疗对转移性结直肠癌患者安全且耐受性良好

Howells Lynne M, Iwuji Chinenye O O, Irving Glen R B, Barber Shaun, Walter Harriet, Sidat Zahirah, Griffin-Teall Nicola, Singh Rajinder, Foreman Nalini, Patel Samita R, Morgan Bruno, Steward William P, Gescher Andreas, Thomas Anne L, Brown Karen

Circulating tumor DNA in patients with colorectal adenomas: assessment of detectability and genetic heterogeneity

结直肠腺瘤患者循环肿瘤DNA:可检测性和遗传异质性的评估

Myint, Ni Ni Moe; Verma, Ajay M; Fernandez-Garcia, Daniel; Sarmah, Panchali; Tarpey, Patrick S; Al-Aqbi, Saif Sattar; Cai, Hong; Trigg, Ricky; West, Kevin; Howells, Lynne M; Thomas, Anne; Brown, Karen; Guttery, David S; Singh, Baljit; Pringle, Howard J; McDermott, Ultan; Shaw, Jacqui A; Rufini, Alessandro

Effects of Omegaven®, EPA, DHA and oxaliplatin on oesophageal adenocarcinoma cell lines growth, cytokine and cell signal biomarkers expression.

Omegaven®、EPA、DHA 和奥沙利铂对食管腺癌细胞系生长、细胞因子和细胞信号生物标志物表达的影响

Eltweri Amar M, Howells Lynne M, Thomas Anne L, Dennison Ashley R, Bowrey David J

Assessing barriers to a rational chemoprevention trial design in young patients with familial adenomatous polyposis

评估针对患有家族性腺瘤性息肉病的年轻患者进行合理化学预防试验设计的障碍

Wood, Joanna P; Howells, Lynne M; Brown, Karen; Thomas, Anne L

Curcumin inhibits cancer stem cell phenotypes in ex vivo models of colorectal liver metastases, and is clinically safe and tolerable in combination with FOLFOX chemotherapy

姜黄素在体外结直肠癌肝转移模型中抑制癌干细胞表型,并且与FOLFOX化疗联合使用具有临床安全性和耐受性。

James, Mark I; Iwuji, Chinenye; Irving, Glen; Karmokar, Ankur; Higgins, Jennifer A; Griffin-Teal, Nicola; Thomas, Anne; Greaves, Peter; Cai, Hong; Patel, Samita R; Morgan, Bruno; Dennison, Ashley; Metcalfe, Matthew; Garcea, Giuseppe; Lloyd, David M; Berry, David P; Steward, William P; Howells, Lynne M; Brown, Karen

Prolonged biologically active colonic tissue levels of curcumin achieved after oral administration--a clinical pilot study including assessment of patient acceptability.

口服给药后,姜黄素在结肠组织中达到持久的生物活性水平——一项包括患者接受度评估的临床试验研究

Irving Glen R B, Howells Lynne M, Sale Stewart, Kralj-Hans Ines, Atkin Wendy S, Clark Susan K, Britton Robert G, Jones Donald J L, Scott Edwina N, Berry David P, Hemingway David, Miller Andrew S, Brown Karen, Gescher Andreas J, Steward William P

Preclinical colorectal cancer chemopreventive efficacy and p53-modulating activity of 3',4',5'-trimethoxyflavonol, a quercetin analogue.

槲皮素类似物 3',4',5'-三甲氧基黄酮醇的临床前结直肠癌化学预防功效和 p53 调节活性

Howells Lynne M, Britton Robert G, Mazzoletti Marco, Greaves Peter, Broggini Massimo, Brown Karen, Steward William P, Gescher Andreas J, Sale Stewart

Growth-inhibitory effects of the chemopreventive agent indole-3-carbinol are increased in combination with the polyamine putrescine in the SW480 colon tumour cell line

在SW480结肠肿瘤细胞系中,化学预防剂吲哚-3-甲醇与多胺腐胺联合使用可增强其生长抑制作用。

Hudson, E Ann; Howells, Lynne M; Gallacher-Horley, Barbara; Fox, Louise H; Gescher, Andreas; Manson, Margaret M