Discovery and Structure-Based Optimization of Benzimidazole-Derived Activators of SOS1-Mediated Nucleotide Exchange on RAS
苯并咪唑衍生物激活剂对 RAS 上 SOS1 介导的核苷酸交换的发现和基于结构的优化
期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.8b01108
Hodges, Timothy R; Abbott, Jason R; Little, Andrew J; Sarkar, Dhruba; Salovich, James M; Howes, Jennifer E; Akan, Denis T; Sai, Jiqing; Arnold, Allison L; Browning, Carrie; Burns, Michael C; Sobolik, Tammy; Sun, Qi; Beesetty, Yugandhar; Coker, Jesse A; Scharn, Dirk; Stadtmueller, Heinz; Rossanese, Olivia W; Phan, Jason; Waterson, Alex G; McConnell, Darryl B; Fesik, Stephen W
