日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Resveratrol protects male Drosophila melanogaster from heat stress-induced paralysis through a mechanism independent of heat shock response activation

白藜芦醇通过一种不依赖于热休克反应激活的机制,保护雄性果蝇免受热应激引起的麻痹。

Webb, Nichole; Bricker, Riley; Skalos, Tyra; Choi, Annette; Shirk, Austin; Hrizo, Stacy L; Buckley, Martin S

Itavastatin and resveratrol increase triosephosphate isomerase protein in a newly identified variant of TPI deficiency

伊伐他汀和白藜芦醇可增加新发现的 TPI 缺乏症变体中的三糖磷酸异构酶蛋白

Andrew P VanDemark, Stacy L Hrizo, Samantha L Eicher, Jules Kowalski, Tracey D Myers, Megan R Pfeifer, Kacie N Riley, Dwight D Koeberl, Michael J Palladino

Identification of protein quality control regulators using a Drosophila model of TPI deficiency

使用果蝇 TPI 缺乏模型鉴定蛋白质质量控制调节剂

Stacy L Hrizo, Samantha L Eicher, Tracey D Myers, Ian McGrath, Andrew P K Wodrich, Hemanth Venkatesh, Daniel Manjooran, Sabrina Swoger, Kim Gagnon, Matthew Bruskin, Maria V Lebedev, Sherry Zheng, Ana Vitantonio, Sungyoun Kim, Zachary J Lamb, Andreas Vogt, Maura R Z Ruzhnikov, Michael J Palladino

A High-Content Screening Assay for Small Molecules That Stabilize Mutant Triose Phosphate Isomerase (TPI) as Treatments for TPI Deficiency

一种用于稳定突变型磷酸三糖异构酶 (TPI) 的小分子的高内涵筛选试验,用于治疗 TPI 缺乏症

Andreas Vogt, Samantha L Eicher, Tracey D Myers, Stacy L Hrizo, Laura L Vollmer, E Michael Meyer, Michael J Palladino

Missense variant in TPI1 (Arg189Gln) causes neurologic deficits through structural changes in the triosephosphate isomerase catalytic site and reduced enzyme levels in vivo

TPI1基因错义变异(Arg189Gln)通过改变磷酸丙糖异构酶催化位点的结构,导致体内酶水平降低,从而引起神经功能缺陷。

Roland, Bartholomew P; Richards, Kristen R; Hrizo, Stacy L; Eicher, Samantha; Barile, Zackery J; Chang, Tien-Chien; Savon, Grace; Bianchi, Paola; Fermo, Elisa; Ricerca, Bianca Maria; Tortorolo, Luca; Vockley, Jerry; VanDemark, Andrew P; Palladino, Michael J

Early mitochondrial dysfunction leads to altered redox chemistry underlying pathogenesis of TPI deficiency

早期线粒体功能障碍导致氧化还原化学改变,这是TPI缺乏症发病机制的基础。

Hrizo, Stacy L; Fisher, Isaac J; Long, Daniel R; Hutton, Joshua A; Liu, Zhaohui; Palladino, Michael J

Hsp70- and Hsp90-mediated proteasomal degradation underlies TPI sugarkill pathogenesis in Drosophila

Hsp70 和 Hsp90 介导的蛋白酶体降解是果蝇 TPI 糖致病机制的基础

Hrizo, Stacy L; Palladino, Michael J