日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Early administration of tecovirimat shortens the time to mpox clearance in a model of human infection

在人类感染模型中，早期使用替考韦瑞特可缩短痘苗病毒清除时间。

期刊:PLoS Biology
影响因子:7.2
doi:10.1371/journal.pbio.3002249
Nguyen, Bach Tran; Marc, Aurélien; Suñer, Clara; Marks, Michael; Ubals, Maria; Hernández-Rodríguez, Águeda; Melendez, María Ángeles; Hruby, Dennis E; Russo, Andrew T; Mentré, France; Mitjà, Oriol; Grosenbach, Douglas W; Guedj, Jérémie
炎症/感染
微生物学
发表日期：2023
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Overview of the regulatory approval of tecovirimat intravenous formulation for treatment of smallpox: potential impact on smallpox outbreak response capabilities, and future tecovirimat development potential

概述特科维瑞马静脉制剂获批用于治疗天花的监管情况：对天花疫情应对能力的潜在影响以及特科维瑞马未来的发展潜力

期刊:Expert Review of Anti-Infective Therapy
影响因子:3.8
doi:10.1080/14787210.2023.2170350
Russo, Andrew T; Grosenbach, Douglas W; Honeychurch, Kady M; Long, Paul G; Hruby, Dennis E
发表日期：2023
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In vitro susceptibility of eighteen clinical isolates of human monkeypox virus to tecovirimat

体外检测18株人猴痘病毒临床分离株对特科维拉特的敏感性

期刊:Memorias Do Instituto Oswaldo Cruz
影响因子:2.5
doi:10.1590/0074-02760230056
Nunes, Desiree Dos Santos; Higa, Luiza M; Oliveira, Régis Linhares; da Costa, Lendel Correia; Bomfim, Larissa Maciel; Gonçalves, Cássia Cristina Alves; Mariani, Diana; Hruby, Dennis E; Voloch, Carolina Moreira; Castiñeiras, Terezinha Marta Pereira Pinto; Tanuri, Amilcar; Damaso, Clarissa R
猴痘
微生物学
发表日期：2023
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An overview of tecovirimat for smallpox treatment and expanded anti-orthopoxvirus applications

特科维瑞特在天花治疗中的应用概述及扩展的抗正痘病毒应用

期刊:Expert Review of Anti-Infective Therapy
影响因子:3.8
doi:10.1080/14787210.2020.1819791
Russo, Andrew T; Grosenbach, Douglas W; Chinsangaram, Jarasvech; Honeychurch, Kady M; Long, Paul G; Lovejoy, Candace; Maiti, Biswajit; Meara, Ingrid; Hruby, Dennis E
微生物学
发表日期：2021
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Oral Tecovirimat for the Treatment of Smallpox

口服替可维瑞特治疗天花

期刊:New England Journal of Medicine
影响因子:78.5
doi:10.1056/NEJMoa1705688
Grosenbach, Douglas W; Honeychurch, Kady; Rose, Eric A; Chinsangaram, Jarasvech; Frimm, Annie; Maiti, Biswajit; Lovejoy, Candace; Meara, Ingrid; Long, Paul; Hruby, Dennis E
发表日期：2018
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Effects of Treatment Delay on Efficacy of Tecovirimat Following Lethal Aerosol Monkeypox Virus Challenge in Cynomolgus Macaques

治疗延迟对食蟹猴感染致命性气溶胶猴痘病毒后Tecovirimat疗效的影响

期刊:Journal of Infectious Diseases
影响因子:4.5
doi:10.1093/infdis/jiy326
Russo, Andrew T; Grosenbach, Douglas W; Brasel, Trevor L; Baker, Robert O; Cawthon, Andrew G; Reynolds, Erin; Bailey, Tara; Kuehl, Philip J; Sugita, Victoria; Agans, Krystle; Hruby, Dennis E
炎症/感染
猴痘
Monkey
微生物学
发表日期：2018
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Treatment with the smallpox antiviral tecovirimat (ST-246) alone or in combination with ACAM2000 vaccination is effective as a postsymptomatic therapy for monkeypox virus infection

单独使用天花抗病毒药物替考韦瑞特（ST-246）或联合ACAM2000疫苗治疗，可有效作为猴痘病毒感染的症状后治疗方法。

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.00208-15
Berhanu, Aklile; Prigge, Jonathan T; Silvera, Peter M; Honeychurch, Kady M; Hruby, Dennis E; Grosenbach, Douglas W
炎症/感染
猴痘
微生物学
发表日期：2015
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ST-246 is a key antiviral to inhibit the viral F13L phospholipase, one of the essential proteins for orthopoxvirus wrapping

ST-246 是一种关键的抗病毒药物，可抑制病毒 F13L 磷脂酶，而 F13L 磷脂酶是正痘病毒包装所必需的蛋白质之一。

期刊:Journal of Antimicrobial Chemotherapy
影响因子:3.6
doi:10.1093/jac/dku545
Duraffour, Sophie; Lorenzo, María M; Zöller, Gudrun; Topalis, Dimitri; Grosenbach, Doug; Hruby, Dennis E; Andrei, Graciela; Blasco, Rafael; Meyer, Hermann; Snoeck, Robert
微生物学
发表日期：2015
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The broad-spectrum antiviral compound ST-669 restricts chlamydial inclusion development and bacterial growth and localizes to host cell lipid droplets within treated cells

广谱抗病毒化合物ST-669可抑制衣原体包涵体的形成和细菌生长，并定位于受处理细胞内的宿主细胞脂滴中。

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.02064-13
Sandoz, Kelsi M; Valiant, William G; Eriksen, Steven G; Hruby, Dennis E; Allen, Robert D 3rd; Rockey, Daniel D
微生物学
细胞生物学
发表日期：2014
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Pharmacokinetic and pharmacodynamic modeling to determine the dose of ST-246 to protect against smallpox in humans

利用药代动力学和药效学模型确定ST-246在人体中预防天花感染的剂量

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.00959-12
Leeds, Janet M; Fenneteau, Frederique; Gosselin, Nathalie H; Mouksassi, Mohamad-Samer; Kassir, Nastya; Marier, J F; Chen, Yali; Grosenbach, Doug; Frimm, Annie E; Honeychurch, Kady M; Chinsangaram, Jarasvech; Tyavanagimatt, Shanthakumar R; Hruby, Dennis E; Jordan, Robert
炎症/感染
发表日期：2013
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